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Table 3 Comparation of geriatric symptom complaints between probable DLB and PDD

From: The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia

Geriatric symptom complaints

DLB

PDD

P1

P2

P3

P4

All

(n = 92)

APOE ε4 (+)

(n = 53)

APOE ε4 (−)

(n = 39)

All

(n = 93)

APOE ε4 (+)

(n = 12)

APOE ε4 (−)

(n = 81)

OH

20 (21.7)

13 (24.5)

7 (17.9)

24 (25.8)

4 (33.3)

20 (24.7)

0.516

0.450

0.523

0.531

Constipation

21 (22.8)

12 (22.6)

9 (23.1)

50 (53.8)

7 (58.3)

43 (53.1)

0.000

0.961

0.734

0.014

Urinary Symptoms

18 (18.9)

12 (22.6)

6 (15.4)

23 (24.7)

2 (16.7)

21 (25.9)

0.398

0.386

0.488

0.649

HH

23 (25.0)

17 (32.1)

5 (12.8)

16 (17.2)

1 (8.3)

15 (18.5)

0.194

0.032

0.383

0.097

Falls

16 (17.4)

10 (18.9)

6 (15.4)

24 (25.8)

4 (33.3)

20 (24.7)

0.164

0.663

0.523

0.271

FoF

18 (19.6)

10 (18.9)

8 (20.5)

42 (45.2)

5 (41.7)

37 (45.7)

0.000

0.844

0.794

0.091

Delusion

32 (34.8)

23 (43.4)

9 (23.1)

5 (5.4)

0 (0.0)

5 (6.2)

0.000

0.043

0.376

0.005

Depression

45 (48.9)

30 (56.6)

15 (38.5)

22 (23.7)

4 (33.3)

18 (22.2)

0.000

0.085

0.398

0.145

Anxiety

46 (50.0)

28 (52.8)

18 (46.2)

17 (18.3)

3 (25.0)

14 (17.3)

0.000

0.527

0.519

0.081

Apathy

42 (45.7)

27 (50.9)

15 (38.5)

15 (16.1)

1 (8.3)

14 (17.3)

0.000

0.235

0.431

0.007

Loss of appetite

35 (38.0)

21 (39.6)

14 (35.9)

2 (2.2)

1 (8.3)

1 (1.2)

0.000

0.716

0.114

0.039

Insomnia

25 (27.2)

17 (32.1)

8 (20.5)

46 (49.5)

7 (58.3)

39 (48.1)

0.002

0.218

0.510

0.089

EDS

17 (18.5)

8 (15.1)

9 (23.1)

11 (11.8)

2 (16.7)

9 (11.1)

0.207

0.330

0.578

0.892

  1. P1 means all DLBs vs. all PDDs
  2. The comparations among the four groups--DLB with APOE ε4 (+), DLB with APOE ε4 (−), PDD with APOE ε4 (+), PDD with APOE ε4 (−) were recorded as P2, P3, P4. The P2 means DLB with APOE ε4 (+) vs. DLB with APOE ε4 (−); P3 means PDD with APOE ε4 (+) vs. PDD with APOE ε4 (−); P4 means DLB with APOE ε4 (+) vs. PDD with APOE ε4 (+), and the P-values were corrected by Bonferroni correction (α = 0.05/4 = 0.0125)
  3. Abbreviations: DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, APOE Apolipoprotein E, OH Orthostatic hypotension, HH Hyperhidrosis, FoF Fear of falling, EDS Excessive daytime sleepiness