The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia

BMC Neurology

Table 4 Associations between APOE ε4 allele and geriatric symptom complaints in DLB and PDD

Characteristics	DLB (APOE ε4 carriers vs. non-carriers)			PDD (APOE ε4 carriers vs. non-carriers)
Characteristics	OR	95%CI	P-value	OR	95%CI	P-value
OH	1.488	0.496–4.461	0.478	1.790	0.426–7.520	0.525
Constipation	0.977	0.341–2.800	0.961	1.435	0.383–5.383	0.592
Urinary Symptoms	1.452	0.448–4.702	0.534	0.773	0.141–2.244	0.767
HH	3.472	1.082–11.144	0.036	0.470	0.050–4.450	0.510
Falls	1.342	0.407–4.428	0.629	1.790	0.426–7.520	0.427
FoF	0.755	0.229–2.484	0.644	1.033	0.262–4.067	0.963
Delusion	1.923	0.669–5.527	0.225	0.000	0.000–0.000	0.998
Depression	3.002	1.079–8.353	0.035	2.110	0.473–9.410	0.328
Anxiety	1.358	0.565–3.266	0.494	1.475	0.309–7.052	0.626
Apathy	1.925	0.760–4.879	0.167	0.655	0.068–6.277	0.714
Loss of appetite	1.311	0.499–3.446	0.582	0.000	0.000–0.000	0.997
Insomnia	1.978	0.671–5.824	0.216	1.838	0.455–7.427	0.393
EDS	0.552	0.162–1.884	0.343	1.375	0.208–9.091	0.741

The models for APOE ε4 carriers vs. non-carriers in DLB and PDD groups were adjusted gender, age at visit, education, habits of smoking and alcohol consumption, heart disease, hypertension, diabetes mellitus, stroke and CDR
Abbreviations: DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, ORs Odds ratios, 95%CI 95% confidence interval, APOE Apolipoprotein E, OH Orthostatic hypotension, HH Hyperhidrosis, FoF Fear of falling, EDS Excessive daytime sleepiness, CDR Clinical Dementia Rating

ISSN: 1471-2377