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Fig. 2 | BMC Neurology

Fig. 2

From: The clinical, myopathological, and molecular characteristics of 26 Chinese patients with dysferlinopathy: a high proportion of misdiagnosis and novel variants

Fig. 2

(A-C) Muscle biopsy from left quadriceps of Patient 1. (A) Modified Gomori trichrome (400×) shows several ragged red fibers (RRF) (arrow). (B) Succinate Dehydrogenase (400×) highlights the ragged blue fiber (RBF) (arrow). (C) Immunohistochemistry staining of muscle fibers shows a complete absence of dysferlin expression (400×). (D) normal control of dysferlin (400×). (E-I) Muscle biopsy from left biceps of Patient 13. (E) Hematoxylin and eosin (HE) (200×) staining shows that inflammatory cells are seen between muscle fibers. Immunohistochemistry staining of muscle fibers shows (F) CD4 positive expression (×200), (G) CD8 negative expression (×200), (H) CD20 positive expression (×200) and (I) CD68 positive expression (×200)

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BMC Neurology

ISSN: 1471-2377

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