Cerebral blood flow abnormalities with central sparing on arterial spin labeling in mild encephalopathy associated with excitotoxicity: a case report

Table 1 Overview of demographic data, clinical symptoms, and imaging

	Demographic data			Clinical symptoms			Imaging			Reference
Diseases	Age	Sex	Pathogens	1st seizure (SE)	IC > 24 h	2nd seizure	MRI	MRS	ASL
CFS	6 months– 6 years	M > F	Rhino, Adeno, Parainflu, Flu	+	-	-	NA	NA	Variable	[16, 17]
MEEX	5 months– 2 years	UK	Rota, HHV-6 Flu	+	+	-	NA	Day 3 Glu↑ Day 3–8 Gln↑	UK	[4, 9]
AESD	10 months– 4 years	M = F	Flu, HHV-6/7 Rota, RSV	+	+	+	Day 1–2 NA Day 3–9 BTA, Central sparing	Day 1–4 Glu↑ Day 4–12 Gln↑	< 24 h CBF↓ Day 3–5 CBF↑	[3, 6, 8, 18]
This case	4 years	F	Parainflu 3 Rhino C	+	+	-	NA	Day 8 Gln↑	33 h Central sparing, CBF↑

AESD Acute encephalopathy with biphasic seizures and late reduced diffusion, ASL Arterial spin labeling, BTA Bright tree appearance, CBF Cereberal blood flow, CFS Complex febrile seizure, F Female, Flu Influenza, Gln Glutamine, Glu Glutamate, HHV-6/7 Human herpesvirus 6/7, IC Impaired consciousness, M, Male, MEEX Mild encephalopathy associated with excitotoxicity, MRS MR spectroscopy, NA No abnormalities, Parainflu, Parainfluenza, RSV respiratory syncytial virus, SE Status epilepticus, UK Unknown

ISSN: 1471-2377