Fig. 7

Comparisons of atrophy and gene-atrophy overlap in GR1 patients and controls. (A.1) Atrophy pattern in the patient with MAPT mutation vs. healthy controls. (A.2) Overlapped gene-atrophy between brain atrophy of patient with MAPT mutation and the expression of MAPT gene in the Allen Atlas. (B.1) Atrophy pattern in the patient with TARDBP mutation vs. healthy controls. (B.2) Overlapped gene-atrophy between brain atrophy of patient with TARDBP mutation and the expression of TARDBP gene in the Allen Atlas. (C.1) Atrophy pattern in the patient with TREM2 risk variant vs. healthy controls. (C.2) Overlapped gene-atrophy between brain atrophy of patient with TREM2 mutation and the expression of TARDBP gene in the Allen Atlas. Graph shows significant results at p < 0.001 uncorrected. Blue-violet dots depict peaks (more than 50 voxels) of overlap