Table 1 Demographic, cognitive, neuropsychiatric and clinical information for patients with different genetic risks

Demographics and clinical information

Age [mean (SD)]

66

48

63

66,99 (5,71)

70,01 (8,76)

68,29 (9,22)

Sex (F:M)

0:01

0:01

1:00

6:06

6:06

5:05

Educational level (years)

20

18

16

13,09 (5,29)

14,04 (6,30)

14,25 (2,38)

Age of Disease onset

58

46

50

58,93 (7,39)

58,89 (8,10)

60,33 (10,52)

Disease duration

8

2

13

8,88 (1,45)

9,39 (2,43)

9,87 (4,85)

Cognitive assessment

Moca

15

14

12

15,17 (7,83)

17,73 (6,52)

18,53 (8,24)

Rey-Osterrieth Figure

22

33

19

23,11 (11,08)

22,07 (10,59)

29,87 (9,73)

Executive functioning

Ineco Frontal Screening

12

12

9

14,28 (6,61)

14,68 (7,51)

18,83 (6,29)

Verbal inhibitory task

19

22

18

23,33 (6,65)

22,77 (12,71)

16,25 (8,46)

Social Cognition

Reading Mind in the eyes

9

8

9

11,41 (2,29)

11,34 (2,73)

12,12 (1,12)

Reading Mind in the faces

9

9

8

10,44 (1,91)

12,89 (1,99)

11,87 (1,24)

Neuropsychiatric Symptoms

Chronic apathy

16

18

21

32,16 (3,53)

21,59 (6,08)

23,12 (9,86)

Chronic disinhibition

18

19

19

28,66 (5,75)

21,52 (5,45)

20,62 (5,45)

Chronic disorganized behavior

28

18

24

37,01 (11,83)

28,70 (7,79)

29,87 (7,79)

Total Chronic Symptoms

62

55

72

76,82 (14,82)

71,61 (11,92)

73,62 (11,38)

Current apathy

38

49

48

40,05 (9,85)

38,11 (10,75)

41,87 (10,34)

Current disinhibition

31

37

39

30,75 (9,35)

30,40 (10,97)

26,98 (8,99)

Current disorganized behavior

47

47

51

55,33 (10,77)

48,93 (14,06)

44,25 (11,06)

Total Current Symptoms

116

133

138

125,66 (11,64)

117,65 (12,89)

118,51 (10,49)