Table 2 Differences between GR1 and GR2 patients and S-FTD (GR3) in cognitive and neuropsychiatric domains

Demographics and clinical information

Age [mean (SD)]

n.s

P < 0.01

P < 0.01

n.s

n.s

Sex (F:M)

n.s

n.s

n.s

n.s

n.s

Educational level (years)

n.s

n.s

n.s

n.s

n.s

Age of Disease onset

n.s

P < 0.01

P < 0.01

n.s

n.s

Disease duration (years)

n.s

P < 0.01

P < 0.01

n.s

n.s

Cognitive assessment

Moca

P < 0.01

P < 0.001

P < 0.05

P < 0.05

n.s

Rey-Osterrieth Figure

P < 0.01

P < 0.001

n.s

P < 0.01

n.s

Executive functioning

Ineco Frontal Screening

P < 0.01

P < 0.001

P < 0.05

P < 0.001

P < 0.05

Verbal inhibitory task

P < 0.05

P < 0.001

P < 0.05

P < 0.001

n.s

Social Cognition

Reading Mind in the eyes

P < 0.05

P < 0.05

P < 0.05

P < 0.05

n.s

Reading Mind in the faces

P < 0.05

P < 0.05

P < 0.05

P < 0.05

n.s

Neuropsychiatric Symptoms

Chronic apathy

n.s

n.s

n.s

P < 0.01

n.s

Chronic disinhibition

P < 0.05

n.s

n.s

P < 0.001

n.s

Chronic disorganized behavior

P < 0.05

n.s

n.s

P < 0.001

n.s

Total Chronic Symptoms

P < 0.05

P < 0.05

n.s

P < 0.01

n.s

Current apathy

n.s

P < 0.05

P < 0.05

n.s

n.s

Current disinhibition

n.s

P < 0.05

n.s

n.s

n.s

Current disorganized behavior

n.s

n.s

P < 0.05

n.s

n.s

Total Current Symptoms

n.s

P < 0.05

P < 0.05

n.s

n.s