Table 1 GSPN schwannoma reports and findings. CN Cranial nerve, F Female, FU follow-up, IQR Interquartile range, y Year, M Male, MFA Middle fossa approach, mo Months, NA not available
Study | Nr. of cases | Age / Sex | Clinical presentation | Surgical approach | Outcome and FU | |||
|---|---|---|---|---|---|---|---|---|
Tremble and Penfield [6] | 1 | 42/M | CN VII palsy hearing loss | mastoidectomy | FU: NA | |||
Kleinsasser and Friedmann [7] | 1 | 19/F | CN VII palsy hearing loss | extradural MFA | FU: 6 mo no changes | |||
Furlow [8] | 2 | 48/M 44/M | seizures CN VII palsy hearing loss | extradural MFA mastoidectomy | FU: 8 mo no changes | |||
Dolenc and Korsic [9] | 1 | 37/M | CN VII palsy hearing loss | extradural MFA | FU: 1 y no changes | |||
Kumon et al. [10] | 1 | 21/F | xerophthalmia CN VII palsy hearing loss | extradural MFA | FU: 1y CN VII palsy improvement hearing loss improvement | |||
Michel et al. [11] | 1 | 20/F | vertigo CN VII palsy hearing loss | extradural MFA | FU: NA CN VII palsy improvement | |||
Kinouchi et al. [12] | 2 | 58/F 49/F | facial pain vertigo | extradural MFA | FU: NA xerophthalmia | |||
Aihara et al. [13] | 1 | 65/M | CN VII palsy | extradural MFA | FU: 6 mo CN VII palsy improvement hearing loss improvement xerophthalmia | |||
Schmidinger and Deinsberger [4] | 1 | 65/F | CN VII palsy hearing loss | extradural MFA | FU: 6 mo hearing unchanged | |||
Mori et al. [14] | 1 | 50/M | hearing loss | extradural MFA | FU: NA no deficit | |||
Sade and Lee [15] | 1 | 63/F | CN VII palsy hearing loss | extradural MFA | FU: NA CN VII palsy improvement hearing loss improvement | |||
Ayberk et al. [16] | 1 | 16/F | diplopia xerophthalmia | extradural MFA | FU: 1 y no deficits | |||
Amirjamshidi et al. [2] | 5 | 22/F 25/M 28/M 28/M 54/F | case 1: seizures case 2: eye pain case 3: eye irritation, headache case 4: eye pain case 5: hysteria, headache | extradural MFA | FU: NA xerophthalmia in two cases | |||
Ichimura et al. [17] | 4 | 25/F 27/M 35/F 49/F | case 1: xerophthalmia case 2: seizures, CN VII palsy Case 3: xerophthalmia, CN VII palsy case 4: xerophthalmia, hearing loss | extra-/intradural MFA | FU: NA CN VII palsy with xerophthalmia in two cases CN VII palsy in one case no new deficits in one case | |||
De Paulis et al. [18] | 1 | 23/F | CN VII palsy hearing loss xerophthalmia | extra-/intradural MFA | FU: NA xerophthalmia | |||
Umredkar et al. [19] | 2 | 51/F | CN VII palsy hearing loss | extradural MFA | FU: 1 y hearing loss improvement CN VII palsy improvement | |||
Uppar et al. [1] | 1 | 39/M | headache xerophthalmia | extradural MFA | FU: 2 y CN VII palsy | |||
Kusumi et al. [20] | 1 | 66/F | vertigo | extra-/intradural MFA | FU: NA no deficits | |||
Ishikawa et al. [21] | 1 | 69/F | gait disturbance | extra-/intradural MFA | FU: NA no deficits | |||
Aftahy et al. (present report) | 4 | 50/F 37/M 35/F 42/F | case 1: CN VII palsy, hearing loss case 2: CN VII palsy case 3: CN VII palsy, hearing loss case 4: CN VII palsy, hearing loss | extradural MFA extra-/intradural MFA mastoidectomy pre-/retrosigmoid approach | FU: 9 mo CN VII palsy improvement in one case hearing loss in one case | |||
Total in n (%) or median [IQR] | 33 | 38y [25;50,5] 20 F (60.6%) 13 M (39.4%) | CN VII palsy facial pain hearing loss seizures xerophthalmia vertigo diplopia seizures eye pain eye irritation headache gait disturbance | 17 (51.5%) 1 (3.0%) 15 (45.5%) 3 (9.1%) 7 (21.2%) 3 (9.1%) 1 (3.0%) 3 (9.1%) 2 (6.1%) 1 (3.0%) 3 (9.1%) 1 (3.0%) | extradural MFA extra-/intradural MFA pre-/retrosigmoid approach mastoidectomy | 15 (45.5%) 5 (15.2%) 1 (3.0%) 3 (9.1%) | median FU CN VII palsy hearing loss xerophthalmia Improvement CN VII palsy Improvement hearing loss | 9 mo [6;12] 4 (12.1%) 1 (3.0%) 7 (21.2%) 6 (18.2%) 4 (12.1%) |