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Table 1  Demographics, clinical and laboratory characteristics of migraine patients and controls

From: The potential impact of insulin resistance and metabolic syndrome on migraine headache characteristics

 

Migraine patients

(n = 30)

Controls

(n = 30)

P-value

Age in years [median (IQR)]

34.5 (27–43)

36.5 (26–41)

0.734 1

Sex [n (%)]

Males

8 (26.7%)

7 (23.3%)

0.766 2

Females

22 (73.3%)

23 (76.7%)

Waist circumference in cm [mean (SD)]

92.43 (11.14)

84.9 (8.42)

0.005* 3

HTN [n (%)]

5 (16.7%)

Attack duration in hours [median (IQR)]

12 (8- 13.75)

Aura [n (%)]

7 (23.3%)

Autonomic manifestations [n (%)]

2 (6.7%)

Allodynia [n (%)]

9 (30%)

MIGSEV Scale [median (IQR)]

Intensity

3 (2–3)

Disability

3 (2–3)

Tolerability

2 (1–2)

Nausea

2 (1–3)

Total score

2 (1–3)

HIT-6 total score [median (IQR)]

59 (49–64)

Laboratory work up [mean (SD)]

FBS

87.87 (12.19)

86.8 (10.6)

0.719 3

TGs

97.4 (49.45)

109.77 (37.97)

0.282 3

HDL

50.51 (11.25)

52.93 (10.76)

0.397 3

Insulin

7.03 (2.997)

5.37 (3.41)

0.049* 3

HOMA-IR

1.72 (0.79)

1.17 (0.81)

0.01* 3

Insulin resistance [n (%)]

14 (46.7%)

5 (16.7%)

0.012* 2

Metabolic syndrome [n (%)]

13 (43.3%)

5 (16.7%)

0.024* 2

  1. FBS Fasting blood sugar, HDL High-density lipoprotein, HIT-6 Headache Impact Test-6, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, HTN Hypertension, MIGSEV Migraine Severity Scale, TGs Triglycerides
  2. 1Mann-Whitney test, 2Chi-squared test, 3Independent sample t-test
  3. *P-value ≤ 0.05 is considered significant