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Fig. 2 | BMC Neurology

Fig. 2

From: Epileptic spasms related to neuronal differentiation factor 2 (NEUROD2) mutation respond to combined vigabatrin and high dose prednisolone therapy

Fig. 2

The evolution of electroencephalography (EEG) of the patient. A Initial EEG consisted of high amplitude multifocal spikes > 50% with bilateral posterior head regions predominance. Ictal pattern characterized by high voltage slow waves superimposed with fast activity (arrow); B the EEG on Day 14 after treatment shows high amplitude slow waves intermixed with spikes in the bilateral posterior head quadrant regions and decreased epileptiform discharges; C the EEG three months after treatment is normal, with well-formed sleep spindles seen; D the EEG at two years of age reveals high amplitude spikes in the bilateral parieto-temporal head regions

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