Fig. 3From: Epileptic spasms related to neuronal differentiation factor 2 (NEUROD2) mutation respond to combined vigabatrin and high dose prednisolone therapyMagnetic resonance imaging (MRI) of the brain was performed at six months when the patient was on vigabatrin and prednisolone. (A) axial diffusion-weighted imaging (DWI); (B) apparent diffusion coefficient (ADC) mapping displaying a restricted diffusion at the bilateral globi pallidi; (C) multivoxel magnetic resonance spectroscopy (MRS) with a short echo time (30 milliseconds) at the left globus pallidus displaying a decrease of N-acetyl aspartate (NAA) and the presence of lactate peak. Brain MRI, T2-weighted images at 26 months of age, shows small hyper signal lesions at (D) bilateral dorsal pons; (E) delayed myelination for age; and (F) small right hippocampusBack to article page