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Fig. 3 | BMC Neurology

Fig. 3

From: Epileptic spasms related to neuronal differentiation factor 2 (NEUROD2) mutation respond to combined vigabatrin and high dose prednisolone therapy

Fig. 3

Magnetic resonance imaging (MRI) of the brain was performed at six months when the patient was on vigabatrin and prednisolone. (A) axial diffusion-weighted imaging (DWI); (B) apparent diffusion coefficient (ADC) mapping displaying a restricted diffusion at the bilateral globi pallidi; (C) multivoxel magnetic resonance spectroscopy (MRS) with a short echo time (30 milliseconds) at the left globus pallidus displaying a decrease of N-acetyl aspartate (NAA) and the presence of lactate peak. Brain MRI, T2-weighted images at 26 months of age, shows small hyper signal lesions at (D) bilateral dorsal pons; (E) delayed myelination for age; and (F) small right hippocampus

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