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Fig. 3 | BMC Neurology

Fig. 3

From: Advanced MRI features of intraventricular inflammatory myofibroblastic tumor: a case report

Fig. 3

Histology and immunohistochemistry of inflammatory myofibroblastic tumor. A Hematoxylin and eosin staining demonstrates that there is a clear demarcation between tumor tissue (black hexagonal star) and peritumoral tissue (red hexagonal star), and the tumor has a relatively complete pseudocapsule (red five-pointed star) (hematoxylin and eosin, × 40). B In the peritumoral tissue, there are abundant blood vessels and infiltration of inflammatory cells. Some regions of lymphocytes aggregate to form follicle-like structures, and some areas of lymphocytes surround the blood vessels to form cuff-like changes (hematoxylin and eosin, × 100). C The pseudocapsule is composed of proliferative fibrous tissue with lymphocyte infiltration (hematoxylin and eosin, × 100). D In the mucinous background, the tumor cells are distributed in bundles and surround blood vessels. The tumor cells are round or oval, with eosinophilic cytoplasm and small nucleoli (hematoxylin and eosin, × 200). E Immunostaining for ALK-1 is weakly positive (× 200). F Immunostaining for Caldesmon is diffuse positive (× 200). Type of equipment for all microscopy images: microscope: Olympus BX43; objective: Olympus Plan N; camera: Olympus DP26, DP26-CU, SN1120809; software: Olympus cellSens Entry

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