Table 1 Baseline characteristics of included patientsa
|  | Tirofiban n = 64 | Without Tirofiban n = 66 | p Value |
|---|---|---|---|
Age, y | 65.8 ± 11.9 | 67.1 ± 13.0 | 0.069 |
Male | 50 (78.1) | 46 (69.7) | 0.321 |
Hypertension | 50 (78.1) | 38(57.6) | 0.012 |
Diabetes | 17 (26.6) | 10 (15.2) | 0.109 |
Hyperlipidemia | 3 (4.7) | 2 (3.0) | 0.678 |
Atrial fibrillation | 7 (10.9) | 18 (27.3) | 0.018 |
Coronary artery disease | 6 (9.4) | 9 (13.6) | 0.447 |
Previous TIA/stroke | 15 (23.4) | 16 (34.8) | 0.192 |
NIHSS on admission | 16 (8–32) | 21 (12–28) | 0.431 |
OTT, min | 314 (195–436) | 240 (155–405) | 0.238 |
SBP | 143 ± 23 | 145 ± 27 | 0.553 |
PT/INR | 0.95 (0.91–1.00) | 1.00 (0.95–1.06) |  < 0.001 |
LDL | 3.1 (2.5–3.6) | 2.7 (2.1–3.1) | 0.011 |
Glucose | 6.6 (5.7–8.5) | 6.7 (5.2–7.8) | 0.566 |
Creatinine | 71 (57–87) | 67 (56–100) | 0.680 |
TOAST classification | |||
 Large artery atherosclerosis | 47 (73.4) | 35 (53.0) | 0.016 |
 Cardioembolism | 11 (17.2) | 25 (37.9) | 0.008 |
 Other | 6 (9.4) | 6 (9.1) | 0.955 |
Occlusion site | |||
 Basilar artery | 28 (43.8) | 37 (56.1) | 0.160 |
 Vertebral artery | 36 (56.3) | 5 (7.6) |  < 0.001 |
TICI ≥ 2b | 54 (84.4) | 40 (74.1) | 0.166 |
Previous IV tPA | 16 (25.0) | 26 (39.4) | 0.079 |
Premorbid mRS(0–2) | 8 (12.3) | 8 (12.6) | 0.919 |