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Table 1 Clinical, demographic and laboratory characteristics of 72 SLE patients

From: Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus Erythematosus

Clinical and demographic characteristics

 Age at study, years, mean (SD)

36.3 (8.9)

 Disease duration, years, median (range)

10 (0–32)

 SLEDAI-2 K, median (range)

2 (0–18)

 SLEDAI-2 K ≥1, n (%)

45 (63%)

 SLEDAI-2 K ≥4, n (%)

18 (25%)

 SLICC/ACR-DI, median (range)

0 (0–5)

 SLICC/ACR-DI ≥1, n (%)

25 (35%)

 NPSLE according to the ACR attribution model, n (%)

44 (61%)

 NPSLE according to the SLICC A attribution model, n (%)

16 (22%)

 NPSLE according to the SLICC B attribution model, n (%)

23 (32%)

 Ongoing glucocorticoid medication, n (%)

57 (79%)

 Ongoing anti-malarial medication, n (%)

57 (79%)

 Ongoing non-antimalarial DMARD medication, n (%)

43 (60%)

 Ongoing antihypertensive medication, n (%)

22 (31%)

 VAS Fatigue, median (range)

62 (1–100)

 Fatigue Severity Scale, median (range)

45 (0–63)

Laboratory analyses

 S-Anti-dsDNA, titer ≥10, n (%)

15 (21%)

 S-Complement factor 3 < 0.8 g/L, n (%)

44 (61%)

 S-Complement factor 4 < 0.16 g/L, n (%)

52 (72%)

 aPL, n (%)

14 (19%)

 P-Creatinine, μg/L, mean (SD)

71 (14)

 eGFR, ml/min/1.73m2, mean (SD)

99 (19)

 eGFR < 60 ml/min/1.73m2, n (%)

2 (3%)

  1. SD Standard deviation, SLEDAI-2 K SLE Disease Activity Index 2000, n Number of subjects, % Proportion of subjects, SLICC Systemic Lupus International Collaborating Clinics, ACR American College of Rheumatology, DI Damage Index, NPSLE Neuropsychiatric SLE, DMARD Disease-modifying antirheumatic drug, VAS Visual Analogue Scale 100 mm, S Serum, Anti-dsDNA Anti-double stranded DNA IgG antibodies, aPL Anti-phospholipid antibodies defined by ongoing positive serology in ≥1: s-anti-cardiolipin-antibodies, s-anti-b2-glycoprotein-1-antibodies, or Lupus Anticoagulant, P Plasma, eGFR estimated glomerular filtration rate