Table 4 Associations between plasma NfL and clinical and laboratory variables in 72 SLE patients

Renal involvement according to SLICC SLE Classification Criteria

29 (40%)

0.069

0.001–0.14

0.047

Anti-dsDNA positive according to SLICC SLE Classification Criteria

44 (61%)

0.077

0.009–0.15

0.027

P-Creatinine

0.003

0.001–0.006

0.009

S-Complement factor 3 < 0.8 g/L

44 (61%)

0.072

0.005–0.14

0.031

S-Complement factor 4 < 0.16 g/L

52 (72%)

−0.015

−0.092-0.061

0.69

SLICC/ACR-DI ≥1

25 (35%)

0.097

0.028–0.17

0.007

SLEDAI-2 K ≥1

45 (63%)

0.063

−0.006-0.13

0.075

SLEDAI-2 K ≥4

18 (25%)

0.023

−0.059-0.10

0.58

Ongoing treatment with glucocorticoids

57 (79%)

0.10

0.022–0.18

0.014

Ongoing treatment with non-antimalarial DMARDs

43 (60%)

0.091

0.025–0.16

0.008

Ongoing treatment with antihypertensives

22 (31%)

0.096

0.026–0.17

0.008