Association between preoperative platelet and 30-day postoperative mortality of adult patients undergoing craniotomy for brain tumors: data from the American College of Surgeons National Surgical Quality Improvement Program database

Table 5 Results of interaction and subgroup analyses

Characteristic	No of participants	OR (95% CI)	P for interaction
Sex			0.7065
Male	8578	0.999 (0.997, 1.000)
Female	9485	0.998 (0.996, 1.000)
Age ranges			0.1822
18–40	2921	0.996 (0.989, 1.004)
41–60	7499	0.997 (0.995, 0.999)
61–80	7046	1.000 (0.998, 1.002)
> 81	597	0.997 (0.993, 1.002)
Diabetes			0.8235
No	15,938	0.999 (0.997, 1.000)
Yes (Noninsulin)	1341	0.999 (0.995, 1.003)
Yes (Insulin)	784	0.997 (0.992, 1.002)
Smoking status			0.7369
No	14,562	0.998 (0.997, 1.000)
Yes	3501	0.999 (0.997, 1.001)
Severe COPD			0.6776
No	17,242	0.999 (0.997, 1.000)
Yes	821	0.998 (0.994, 1.002)
Hypertension			0.5515
No	11,158	0.998 (0.996, 1.000)
Yes	6905	0.999 (0.997, 1.001)
Steroid use for chronic condition			0.9858
No	15,325	0.999 (0.997, 1.000)
Yes	2738	0.999 (0.996, 1.001)
Bleeding disorders			0.2669
No	17,690	0.999 (0.998, 1.000)
Yes	373	0.994 (0.984, 1.003)
Pre-operation transfusions			0.2426
No	18,000	0.999 (0.997, 1.000)
Yes	63	1.003 (0.996, 1.011)
Emergency case			0.0110
No	16,873	0.998 (0.996, 0.999)
Yes	1190	1.002 (0.999, 1.005)
WBC			0.2615
WBC ≤ 10	6459	0.998 (0.996, 1.000)
WBC > 10	11,604	1.000 (0.997, 1.002)

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