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Fig. 2 | BMC Neurology

Fig. 2

From: Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report

Fig. 2

Histopathological features of irreversible MIE. a A coronal section of the splenium shows brownish discoloration. b Klüver-Barrera (KB) staining in the rectangle in (a) reveals severe demyelination in the splenium of the corpus callosum (asterisk), in contrast to the cingulum (white asterisk). Severe demyelination with foamy macrophages (arrowheads, c) and moderate loss of axons with swelling (arrows, d). Bars = 1 cm (a); 100 μm (b); 20 μm (c, d). (b, c) KB staining; (d) immunohistochemistry with anti-neurofilament antibody

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BMC Neurology

ISSN: 1471-2377

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