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Table 3 Examination of factors affecting restenosis by logistic univariate analysis

From: Long-term outcome and factors associated with restenosis after combination therapy of balloon angioplasty and stenting for symptomatic intracranial stenosis

 

Restenosis

Non-restenosis

P value

N(%)

42 (26.3)

118 (73.8)

 

 N

42

118

 

Age

 Mean ± SD, y

65.9 ± 11.3

68.2 ± 11.2

0.2499

 Median

69 (58–74)

70.0 (62–76)

 

Sex

 Male

34 (27.4)

90 (72.6)

0.5335

 Female

8 (22.2)

28 (77.8)

 

Vascular risk factors

 Hypertension

37 (26.6)

102 (73.4)

0.7852

 Dyslipidemia

27 (25.2)

80 (74.8)

0.6781

 Diabetes mellitus

23 (37.7)

38 (62.3)

0.0108

 Coronary artery disease

12 (41.4)

17 (58.6)

0.0443

 Chronic kidney disease

3 (25.0)

9 (75.0)

0.9185

Medication

 Aspirin

36 (27.5)

95 (72.5)

0.4539

 Clopidogrel

33 (23.6)

107 (76.4)

0.0471

 Cilostazol

6 (22.2)

21 (77.8)

0.6026

Stenotic artery

  

0.7582

 Middle cerebral artery

17 (25.0)

51 (75.0)

 

 Internal cerebral artery

16 (32.7)

33 (67.3)

 

  C1-2

4 (40.0)

6 (60.0)

 

  C3-4

2 (16.7)

10 (83.3)

 

  C5

10 (37.0)

17 (63.0)

 

 Vertebral artery

7 (22.6)

24 (77.4)

 

 Basilar artery

2 (16.7)

10 (83.3)

 

Symptom

 Cerebral infarction

33 (28.0)

85 (72.0)

0.4098

 TIA

9 (21.4)

33 (78.6)

 

Last attack to treatment, day

 Mean ± SD

34.5 ± 33.3

30.7 ± 33.9

0.5412

 Median

30 (11–50)

21 (14–30)

 

Stenosis rate: pretreatment, %

 Mean ± SD

78.6 ± 9.2

78.1 ± 8.6

0.7357

 Median

80 (70–85)

80 (70–80)

 

Stenosis rate: posttreatment, %

 Mean ± SD

31.8 ± 11.1

24.7 ± 13.6

0.0039

 Median

30 (25–40)

20 (15–30)

 

Length of lesion, mm

 Mean ± SD

9.0 ± 3.6

8.1 ± 3.1

0.1404

 Median

8.0 (7–11)

7.5 (6–9)

 

Morphology of lesion

 Eccentric

23 (32.4)

48 (67.6)

0.1166

 Concentric

19 (21.3)

70 (78.7)

 

Max diameter of balloon/stent, mm

 Mean ± SD

2.5 ± 0.8

2.8 ± 0.9

0.0568

 Median

2.3 (2.0–3.0)

2.5 (2.0–3.5)

 

Primary procedures

 Balloon angioplasty

35 (34.7)

66 (65.3)

0.0025

 Stenting

7 (11.9)

52 (88.1)

 

Recurrence of ischemic events

6 (42.9)

8 (57.1)

0.1479

 TIA

3 (50.0)

3 (50.0)

0.1965

 Ischemic stroke

3 (37.5)

5 (62.5)

0.4626