Fig. 2From: Fatal thrombolysis-related intracerebral haemorrhage associated with amyloid-β-related angiitis in a middle-aged patient – case report and literature reviewHistology of amyloid-β-related angiitis (ABRA). The leptomeningeal arteries show homogenous eosinophilic thickening, in keeping with marked cerebral amyloid angiopathy (CAA), surrounded by mild chronic inflammation by haematoxylin-eosin (HE) staining (a). Obliterated artery with haemosiderin deposition and old microinfarct in the left occipital lobe (b). Immunohistochemistry for amyloid-β confirms CAA and granulomatous inflammation with a multinucleated giant cell (arrow) is evident (c). Immunohistochemistry for CD68 demonstrates numerous perivascular macrophages and a giant cell invading the vessel wall (d)Back to article page