Fig. 6

Clinical impact curve (CIC) of nomogram model. The red curve (number of high-risk individuals) indicates the number of people who are classified as positive (high risk) by the model at each threshold probability; the blue curve (number of high-risk individuals with outcome) is the number of true positives at each threshold probability. CIC visually indicated that the nomogram conferred high clinical net benefit and confirmed the clinical value of the nomogram model