Table 1 Participant characteristics and univariate analysis to identify independent predictors of functional outcome in young adults 6-months post-intracerebral haemorrhage. (Continuous variables were reported as the means ± SD or medians (IQR). Categorical variables were reported as n (%))

Demographics

 Age (ys)

42.6 ± 7.1

42.2 ± 7.3

44.2 ± 6.5

 < 0.001^***

 Sex

 < 0.01^**

 Male sex

385(68.1%)

317(70.8%)

68(58.1%)

 Female sex

180(31.9%)

131(29.2%)

49(41.9%)

 Vascular cause

70(12.4%)

58(12.9%)

12(10.3%)

0.427

History of diseases

 Hypertension

331(58.6%)

253(56.5%)

78(66.7%)

 < 0.05^*

 Diabetes mellitus

29(5.1%)

23(5.1%)

6(5.1%)

0.998

 Coronary heart disease

11(2.0%)

9(2.0%)

2(1.7%)

1

 Atrial fibrillation

2(0.4%)

25(5.6%)

3(2.6%)

0.306

 Oral anticoagulation

8(1.4%)

5(1.1%)

3(2.6%)

0.459

 Previous stroke

45(8.0%)

35(7.8%)

10(8.5%)

0.795

Lifestyle

 Heavy smoking

178(31.5%)

143(31.9%)

35(29.9%)

0.678

 Alcohol abuse

157(69.6%)

130(29%)

27(23.1%)

0.201

Hematoma volume(ml)

13.7(5.8–29.6)

12.1(4.9–26.3)

21.6(8.4–41.4)

 < 0.001^***

Hematoma location

 Lobar lesion

164(29.0%)

127(28.3%)

37(31.6%)

0.487

 Basal ganglion lesion

145(25.66%)

113(25.2%)

32(27.4%)

0.639

 Infratentorial lesion

38(6.73%)

26(5.8%)

12(10.3%)

0.087

 Multiple hemorrhages

6(1.0%)

4(0.9%)

2(1.7%)

0.443

 Intraventricular extension

146(25.8%)

109(24.3%)

37(31.6%)

0.304

 Subarachnoid space extension

45(8.0%)

33(7.4%)

12(10.3%)

0.109

Systolic blood pressure (mmHg)

152(135–171)

152(133–171)

152(137–177)

0.606

Diastolic blood pressure (mmHg)

94(81–107)

94(81–107)

94(82–108)

0.926

Laboratory data at admission

 Blood glucose(mg/dl)

111.6(95.4–135)

108(93.6–120.6)

120.6(104.4–167.4)

 < 0.001^***

 WBC(10⁹/L)

10.0(7.4–12.9)

9.7(7.3–12.3)

11.9(8.5–15.1)

 < 0.001^***

 Hemoglobin(mg/dl)

14.4(13.2–15.4)

14.4(13.3–15.4)

14.3(12.6–15.1)

 < 0.01^**

 PLT(10⁹/L)

207(175–245)

205(175–245)

207(162–249)

0.997

 AST(U/L)

19(15–26)

19(15–24`)

22(16–31)

 < 0.01^**

 eGFR, mL/min/1.73m²

102.4(82.2–114.2)

102.7(83.5–115.7)

97.7(67.2–112.3)

0.105

Surgical treatment

172(30.44%)

123(27.5%)

49(41.9%)

 < 0.01^**

GCS

14(10–15)

14(12–15)

10(7–14)

 < 0.001^***

NIHSS

11(4–16)

9(3–15)

18(11–25)

 < 0.001^***

ICH score

1(1–2)

1(1–2)

2(1–3)

 < 0.001^***

ICH-FOS

3(1–5)

3(1–5)

6(3–8)

 < 0.001^***