Skip to main content

Table 2 Characteristics and prognosis of patients with infratentorial recurrence (ITR)

From: Clinical characteristics and prognosis of Glioblastoma patients with infratentorial recurrence

Patient

ITR location

Symptoms at ITR diagnosis

KPS

Surgery and Radiotherapy

Chemotherapy

PFS (M)

OS (M)

PRS (M)

1

Fourth ventricle

Gait disturbance, dizziness, nausea, cerebellar mutism

70

LBRT 60 Gy/30Fr

TMZ

14.3

21.9

7.6

2

Fourth ventricle

Gait disturbance, dizziness, nausea

40

LBRT 25 Gy/5Fr

Bev

11.2

14.0

2.7

3

Right Flocculus

Fourth ventricle

Gait disturbance

50

None

TMZ + Procarbazine

8.2

11.7

3.4

4

Left cerebellar hemisphere

Gait disturbance

70

Surgery + LBRT 60 Gy/30Fr

TMZ

12.1

19.7

7.6

5

Left cerebellar hemisphere

Gait disturbance, dizziness

70

LBRT 25 Gy/5Fr

TMZ + Bev

16.1

24.7

8.6

6

Fourth ventricle

Right cerebellar hemisphere

Left tectum of midbrain

Gait disturbance

50

Cerebellum to whole spine 36 Gy/20Fr

Bev

12.2

15.1

2.9

  1. Bev Bevacizumab, KPS Karnofsky performance status, LBRT Local brain radiotherapy, OS Overall survival, PFS Progression free survival, PRS Post-recurrence survival, TMZ Temozolomide