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Table 2 Comparison of maximum cytokine levels within 0–23 h and 24–47 h after onset

From: Time course of serum cytokine level changes within 72 h after onset in children with acute encephalopathy and febrile seizures

Cytokine

Max cytokine level in 0–23 h

Max cytokine level in 24–47 h

P value

Median

Range

Median

Range

 

IL-1β (pg/mL)

11.4

(4.6–107.8)

2.3

(1.0–24.5)

0.07

IL-1RA (pg/mL)

37,173.2

(764.0–60,163.6)

9261.1

(481.4–78,583.5)

0.39

IL-4 (pg/mL)

4.7

(1.1–9.2)

1.9

(1.2–3.6)

0.39

IL-5 (pg/mL)

56.1

(7.1–106.8)

8.0

(7.6–53.5)

0.23

IL-6 (pg/mL)

1165.8

(21.3–3438.7)

18.4

(4.0–1491.2)

0.04

IL-8 (pg/mL)

612.2

(227.5–4176.7)

193.2

(75.8–1408.7)

0.13

IL-10 (pg/mL)

126.8

(23.0–1196.8)

93.4

(7.0–807.0)

0.31

IL-17 (pg/mL)

22.9

(6.4–405.2)

6.2

(4.2–222.5)

0.18

Eotaxin (pg/mL)

111.4

(62.1–438.0)

105.2

(53.5–222.5)

0.82

FGF (pg/mL)

52.5

(24.6–108.6)

32.5

(17.9–55.5)

0.18

GCFS (pg/mL)

4104.2

(114.1–16,389.2)

223.7

(101.2–14,969.2)

0.20

IFN-γ (pg/mL)

34.0

(3.8–84.4)

4.4

(2.6–37.1)

0.13

IP-10 (pg/mL)

12,996.3

(663.3–29,227.7)

4252.8

(1346.0–17,348.6)

0.31

MCP-1 (pg/mL)

1701.6

(96.9–5238.8)

303.3

(159.6–1444.0)

0.31

MIP-1α (pg/mL)

17.9

(8.1–28.3)

8.4

(4.6–87.6)

0.18

PDGF-bb (pg/mL)

11,168.3

(551.1–21,539.5)

7328.7

(893.3–19,659.5)

0.39

  1. Data are expressed as median (range)
  2. Abbreviations: IL interleukin, RA receptor agonist, FGF fibroblast growth factor, GCSF granulocyte colony-stimulating factor, IFN-γ interferon gamma, IP-10 interferon-inducible protein-10, MCP-1 monocyte chemoattractant protein-1, MIP-1α macrophage inflammatory protein-1α, PDFG-bb platelet-derived growth factor-bb