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Table 2 Predictors of poor neurological outcome: univariate Cox analysis

From: Multimodal ultrasound-based carotid plaque risk biomarkers predict poor functional outcome in patients with ischemic stroke or TIA

outcomes

mRS score 2–6

mRS score 3–6

Variables

HR

95%CI

P

HR

95%CI

P

Age, years

1.17

0.79–1.71

0.438

1.97

1.04–3.75

0.039

Sex (male)

1.51

0.51–4.47

0.462

1.42

0.30–6.67

0.660

Body mass index, kg/m2

1.22

0.83–1.79

0.306

1.03

0.59–1.79

0.914

Smoking

1.11

0.43–2.86

0.827

1.78

0.38–8.37

0.467

Drinking alcohol

1.03

0.41–2.66

0.947

0.96

0.25–3.73

0.957

Hypertension

1.61

0.65–3.99

0.303

1.21

0.34–4.28

0.769

Diabetes mellitus

1.74

0.72–4.19

0.219

1.88

0.53–6.67

0.327

Dyslipidemia

0.78

0.33–1.84

0.560

0.44

0.11–1.71

0.237

Coronary heart disease

1.29

0.53–3.11

0.572

2.09

0.61–7.24

0.242

Anti-platelet drugs

0.82

0.24–2.85

0.759

0.34

0.08–1.41

0.333

Anti-hypertensive

0.62

0.21–1.82

0.386

0.30

0.07–1.20

0.088

Statin

0.67

0.18–2.69

0.573

0.34

0.07–1.63

0.178

Degree of stenosis

1.13

0.42–3.09

0.807

0.53

0.15–1.88

0.327

Plaque thickness,(cm)

0.92

0.62–1.36

0.682

0.72

0.39–1.30

0.278

Plaque area,(cm2)

0.92

0.63–1.34

0.650

1.04

0.61–1.79

0.881

Plaque length,(cm)

1.11

0.75–1.63

0.605

1.59

0.88–2.91

0.125

Calcified plaque

0.64

0.27–1.53

0.316

0.86

0.25–2.96

0.807

Echo of plaque

0.71

0.42–1.19

0.188

0.57

0.26–1.26

0.163

Plaque surface morphology

1.12

0.58–2.17

0.742

1.42

0.54–3.75

0.473

Neovascularization level

3.66

1.52–8.82

0.004

9.0

1.91–42.38

0.005

Plaque hardness

0.53

0.34–0.83

0.006

0.61

0.33–1.13

0.117