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Table 1 Comparison of AIS patients receiving intravenous thrombolysis in 2020 and 2021

From: The effects of the coronavirus disease pandemic on intravenous thrombolytic therapy among patients with acute ischemic stroke in Dalian, China

Characteristics

2020

(n = 735)

2021

(n = 1719)

U/χ2

P value

Sex [n (%)]

 Male

507 (69.0)

1122 (65.3)

3.174

0.075

 Female

228 (31.0)

597 (34.7)

Age (years, median (P25, P75)

68 (61, 74)

67 (59, 75)

611,432

0.207

Mode of transportation to the hospital [n (%)]

 No ambulance support

617 (83.9)

1394 (81.1)

8.695

0.034

 Nosocomial attacks

2 (0.3)

20 (1.2)

 "120″ ambulance services

107 (14.6)

293 (17)

 Transferred from other hospitals

9 (1.2)

12 (0.7)

Before thrombolysis

NIHSS (score, median (P25, P50))

5 (3, 11)

5 (2, 10)

598,775

0.040

ODT (min, median (P25, P75))

100 (60, 155)

112 (61, 160)

595,541

0.024

ONT (min, median (P25, P75))

165 (127, 225)

160 (116, 210)

581,733

0.002

DNT (min, median (P25, P75))

59 (44, 80)

45 (32, 59)

419,387

< 0.001

Name of thrombolytic drug [n(%)]

 Urokinase

121 (16.5)

266 (15.5)

0.379

0.538

 Alteplase

614 (83.5)

1453 (84.5)

  1. AIS Acute ischemic stroke, NIHSS National Institutes of Health Stroke Scale, ODT onset-to-door time, DNT Door-to-needle time, ONT Onset-to-needle time