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Table 2 Motor function of SMA patients before and after treatment

From: Assessment of motor function and nutritional status in children with spinal muscular atrophy treated with nusinersen after loading period in Western China: a retrospective study

 

SMA type 1

SMA type2

SMA type 3

CHOP-INTEND

HINE-2

RULM

HFMSE

RULM

HFMSE

6MWT (m)

Number

6

6

20

22

6

5

5

Baseline

19.5 (11.9)

4.0 (2.9)

15.8 (8.7)

12.5 (9.8)

29.3 (4.8)

44.2 (11.4)

199.9 (196.7)

Day 63

20.5 (12.1)

4.5 (3.6)

17.6 (9.3)

15.0 (10.6)

32.7 (2.7)

47.2 (11.6)

226.3 (236.5)

P-value

0.416

0.416

0.004

0.000

0.042

0.176

0.345

  1. CHOP-INTEND Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorder, HINE-2 modified Hammersmith Infant Neurologic Examination-Part 2, RULM Revised Upper Limb Module, HFMSE Hammersmith Functional Motor Scale Expanded, 6MWT 6-Minute Walking test, m meters