Skip to main content

Table 2 Summary risk estimates of the subgroup analysis results of ICAC and stroke occurrence

From: Intracranial artery calcification as an independent predictor of ischemic stroke: a systematic review and a meta-analysis

Subgroup

Studies (n)

OR (95%CI)

I2 (%)

P value

Total

8

1.62 (1.18, 2.23)

82.3

<  0.01

Design

    

 Case-control study

5

1.79 (1.12, 2.86)

88.4

<  0.01

 Cohort study

3

1.42 (1.09, 1.85)

0

<  0.01

Location

    

 Asia

3

1.66 (0.90, 3.08)

91.3

0.10

 Europe

3

1.52 (1.20, 1.92)

0

<  0.01

 North America

2

2.09 (1.18, 3.69)

0

0.01

Risk of bias

    

 Low

3

1.41 (0.89, 2.25)

90

0.14

 Moderate

5

1.66 (0.90, 3.08)

2.8

<  0.01

No. of cases

    

  < 500

4

2.08 (1.60, 2.70)

0

<  0.01

  > 500

4

1.33 (0.99, 1.79)

73.9

0.06

  1. Abbreviations: OR odds ratio, CI confidence intervals