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Fig. 2 | BMC Neurology

Fig. 2

From: A case report of autoimmune GFAP astrocytopathy presenting with abnormal heart rate variability and blood pressure variability

Fig. 2

Cell-based assay of GFAP-transfected HEK293 cells and tissue-based immunofluorescence assay of CSF GFAP-IgG using rat brain. (a) HEK293 cells expressing green fluorescent protein (GFP)-labeled GFAP. (b) GFAP-IgG detected in CSF of patients; (c) Red fluorescence overlapping with specific sites of green fluorescence cells. Astrocyte fluorescence is widespread in the cortex (d) and hippocampus (e), and meningeal fluorescence is enhanced. Linear fluorescence is observed throughout the molecular layer in the cerebellum (f), and astrocyte fluorescence is observed in the granular layer and white matter

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