Neutrophil to High-density Lipoprotein ratio (NHR) as a potential predictor of disease severity and survival time in Creutzfeldt-Jakob disease

Table 1 Clinical and inflammatory biomarkers data of participants

Characteristic	Overall (n = 88)
Age (y), median (IQR)	62.0 (57.0–66.0)
Sex (Male/Female)	59/29
Barth Index, median (IQR)	45.0 (20.0–75.0)
Survival time (m), median (IQR)	12.5 (5.0–25.8)
NSE in plasma (ng/ml), median (IQR)	18.4 (14.3–26.1)
PSWCs on EEG, positive/total n (%)	22/81 (27.2%)
Hyperintense of basal ganglia on MRI, positive/total n (%)	22/88 (25%)
CSF 14–3-3 protein, positive/total n (%)	36/75 (48%)
Inflammatory
NLR, median (IQR)	2.0 (1.5–2.6)
HDL (mmol/L), mean (± SD)	1.4 (± 0.4)
NHR, median (IQR)	2.5 (1.7–3.3)
MHR, median (IQR)	0.2 (0.2–0.3)

Continuous data were presented as the mean (± standard deviation[SD]) for normally distributed data and as median (interquartile range[IQR]) for non-normally distributed data. Categorical data were described as the frequency/total n (percentage)
NSE Neuron-specific enolase, PSWCs Periodic sharp wave complexes, NLR Neutrophil-to-lymphocyte ratio, HDL High-density lipoprotein, NHR Neutrophil to high-density lipoprotein ratio, MHR Monocyte to high-density lipoprotein ratio

ISSN: 1471-2377