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Table 5 Relationships between HbA1c and PSCI in various subgroups

From: Nonlinear relationship between glycated hemoglobin and cognitive impairment after acute mild ischemic stroke

Subgroup

No. of subjects

Odds ratio (95% CI)

P-value

P for interaction

Age, year

   

0.9746

 23—63

103

1.19 (0.80, 1.78)

0.3945

 

 64—73

100

1.14 (0.75, 1.72)

0.5362

 

 74—96

108

1.13 (0.77, 1.66)

0.5264

 

Gender

   

0.3913

 Male

198

1.25 (0.88, 1.78)

0.2117

 

 Female

113

1.05 (0.74, 1.49)

0.7701

 

BMI, kg/m2

   

0.6970

 15.63—21.61

103

1.04 (0.71, 1.53)

0.8396

 

 21.64—23.83

100

1.27 (0.85, 1.90)

0.2487

 

 23.88—33.33

108

1.21 (0.78, 1.89)

0.3905

 

Education

   

0.2517

 Undergraduate, college or above

10

0.05 (0.00, 4.26)

0.1910

 

 High school (including technical secondary school)

19

1.10 (0.30, 4.10)

0.8861

 

 Junior high school

64

1.03 (0.68, 1.56)

0.8915

 

 Primary school

133

1.10 (0.88, 1.38)

0.7321

 

 Illiteracy

85

1.64 (0.99, 2.71)

0.0555

 

Smoking status,

   

0.1512

 Never-smoker

218

1.08 (0.93, 1.24)

0.5473

 

 Past smoker who has quit

45

1.86 (0.95, 3.66)

0.0710

 

 Current smoker

48

0.78 (0.36, 1.67)

0.5222

 

Alcohol consumption

   

0.6461

 Yes

73

1.29 (0.72, 2.33)

0.3974

 

 No

238

1.13 (0.84, 1.52)

0.4316

 

Hypertension

   

0.4415

 Yes

185

1.24 (0.88, 1.75)

0.2250

 

 No

126

1.06 (0.75, 1.50)

0.7476

 

Diabetes mellitus

   

0.2544

 Yes

58

1.34 (0.87, 2.08)

0.1846

 

 No

253

1.00 (0.71, 1.42)

0.9931

 

Hyperlipidemia

   

0.6520

 Yes

11

1.34 (0.60, 2.97)

0.4770

 

 No

300

1.11 (0.83, 1.48)

0.4737

 

mRS score

   

0.1269

 0–2

270

1.17 (0.88, 1.58)

0.2839

 

 3–4

41

0.65 (0.32, 1.35)

0.2504

 

NIHSS score

   

0.7445

 0

40

0.76 (0.28, 2.05)

0.5844

 

 1

87

1.24 (0.79, 1.96)

0.3477

 

 2

104

1.20 (0.82, 1.75)

0.3424

 

 3

80

1.09 (0.74, 1.61)

0.6744

 
  1. Above model adjusted for Age, Sex, BMI, Education level, Smoking Status, Drinking Status, Hypertension, Diabetes mellitus, Atrial fibrillation, HDL, LDL, TG, TC, FPG, UA, Hyperlipidemia, HCY, Cr, BUN, hs-CRP, mRS, and NIHSS. In each case, the model is not adjusted for the stratification variable