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Table 2 Laboratory and imaging information of the patients that received IVT treatment

From: Intravenous thrombolysis for acute ischemic stroke during two COVID-19 outbreaks in China: Wuhan pandemic and Beijing pandemic

 

Overall (n = 440)

Pre-COVID-19 (n = 258)

Wuhan pandemic (n = 55)

Post-Wuhan (n = 32)

Beijing pandemic (n = 35)

Post-Beijing (n = 60)

P value

Serum glucose level (mmol/L), median [IQR]

6.89 [5.89–8.75]

6.84 [5.89–8.62]

7.19 [5.97–9.29]

6.84 [5.57–8.01]

6.55 [5.92–8.09]

7.50 [6.01–9.30]

.616

HbA1c (%), median [IQR]

6.00 [5.70–6.82]

6.00 [5.70–6.60]

6.00 [5.65–7.10]

6.25 [5.62–7.20]

5.95 [5.80–6.30]

6.20 [5.75–6.90]

.75

LDL level (mmol/L), mean (SD)

2.56 ± 0.84

2.68 ± 0.81

2.79 ± 0.95

2.44 ± 0.85

2.27 ± 0.87

2.19 ± 0.62

.001

Cholesterol level (mmol/L), mean (SD)

4.18 ± 0.97

4.30 ± 0.92

4.49 ± 1.07

4.09 ± 1.04

3.76 ± 0.93

3.75 ± 0.81

.001

ASPECTS score, median [IQR]

8 [7–9]

9 [8-9]

10 [10-10]

9 [8–10]

8 [7–9]

8 [6–9]

.279

MR DWI positive, n(%)

297 (86.6)

166 (83.8)

38 (86.4)

24 (92.3)

25 (89.3)

44 (93.6)

.323

Fazekas scale, median [IQR]

1 [1-2]

1 [1-1]

1 [1-2]

1 [1-2]

2 [1-2]

1 [1-2]

.001

Cranial vessel stenosis location, n(%)

      

.110

ACA

5 (3.2)

3 (3.5)

0 (0.0)

0 (0.0)

0 (0.0)

2 (7.7)

 

MCA

77 (50.0)

43 (50.0)

10 (58.8)

4 (12.5)

7 (53.8)

13 (50.0)

 

PCA

15 (9.7)

10 (11.6)

3 (17.6)

2 (16.7)

0 (0.0)

0 (0.0)

 

ICA

38 (24.7)

22 (25.6)

2 (11.8)

5 (41.7)

4 (30.8)

5 (19.2)

 

VA

3 (1.9)

1 (1.2)

0 (0.0)

1 (8.3)

1 (7.7)

0 (0.0)

 

BA

16 (10.4)

7 (8.1)

2 (11.8)

0 (0.0)

1 (7.7)

6 (23.1)

 

Stenosis degree, n(%)

      

.548

 ≤ 70%

302 (68.8)

176 (68.2)

38 (69.1)

20 (62.5)

23 (65.7)

45 (75.0)

 

70–99%

50 (11.4)

33 (12.8)

7 (12.7)

5 (15.6)

2 (5.7)

3 (5.0)

 

Occlusion

88 (20.0)

49 (19.0)

10 (18.2)

7 (21.9)

10 (28.6)

12 (20.0)

 

sICH-ECASS II, n(%)

17 (3.9)

4 (1.6)

5 (9.1)

0 (0.0)

1 (2.9)

7 (11.7)

.002

sICH-SITS, n(%)

10 (2.3)

2 (0.8)

4 (7.3)

0 (0.0)

0 (0.0)

4 (6.7)

.001

  1. LDL low density lipoprotein, ASPECTS alberta stroke program early CT score, DWI diffusion weighted imaging, ACA anterior cerebral artery, MCA middle cerebral artery, PCA posterior cerebral artery, ICA internal carotid artery, VA vertebral artery, BA basal artery, sICH symptomatic intracerebral hemorrhage, ECASS European cooperative acute stroke study, SITS safe implementation of thrombolysis in stroke