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Table 2 EEG abnormalities found in patients with young onset Alzheimer’s disease or young onset frontotemporal dementia, including sensitivity, specificity, positive predictive values and negative predictive values and likelihood ratios

From: Electroencephalography in young onset dementia

 

Alzheimer’s disease

(n = 103)

Frontotemporal dementia

(n = 28)

Healthy controls

(n = 100)

N without EEG abnormality**

12 (11.7%)

13 (46.4%)

96 (96.0%)

N with slow wave changes**

89 (86.4%)+

12 (42.9%)++

3 (3.0%)

N with epileptiform changes

40 (38.8%)+++

8 (28.6%)++++

1 (1.0%)

  1. * P < 0.05
  2. ** P < 0.001
  3. + sensitivity 86.4%; specificity 97.0%; positive predictive value 1.10%; negative predictive value 100%; PLR = 28.8, NLR = 0.14
  4. ++ sensitivity 42.9%; specificity 97.0%; positive predictive value 0.03%; negative predictive value 100%; PLR = 14.3, NLR = 0.59
  5. +++ sensitivity 38.8%; specificity 99.0%; positive predictive value 1.50%; negative predictive value 100%; PLR = 38.8, NLR = 0.62
  6. ++++ sensitivity 28.6%; specificity 99.0%; positive predictive value 0.06%; negative predictive value 100%; PLR = 28.6, NLR = 0.72
  7. (PLR = positive likelihood ratio; NLR = negative likelihood ratio)
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BMC Neurology

ISSN: 1471-2377

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