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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging.

    Authors: Yuanzhi Li, Zhenfa Li, Ligang Song, Weimin Xie, Xianghao Gong, Dongliang He and Xin Zhang

    Citation: BMC Neurology 2020 20:289

    Content type: Research article

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  2. Atherosclerosis of the internal carotid artery (ICA) is an important cause of ischemic stroke. Artery-to-artery embolism is the major stroke mechanism in patients with atherosclerotic carotid disease. This stu...

    Authors: Ho Geol Woo, Sung Hyuk Heo, Eui Jong Kim, Dae-il Chang, Tae Jin Song and Bum Joon Kim

    Citation: BMC Neurology 2020 20:288

    Content type: Research article

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  3. Surgical treatment of anterior communicating artery (Acom) aneurysm is challenging due to anatomic complexity. We aimed to describe our experiences with endovascular treatment (EVT) of Acom aneurysms, and to ev.....

    Authors: Chang Ki Jang, Joonho Chung, Jae Whan Lee, Seung Kon Huh, Nak-Hoon Son and Keun Young Park

    Citation: BMC Neurology 2020 20:287

    Content type: Research article

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  4. Patients with vascular Ehlers-Danlos syndrome (EDS) occasionally suffer from arterial dissection. Eagle syndrome, which is caused by an elongated styloid process and also causes arterial dissection, is difficu...

    Authors: Hajime Ikenouchi, Masahito Takagi, Ayako Nishimura, Eriko Yamaguchi, Junpei Koge, Kozue Saito, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2020 20:285

    Content type: Case report

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  5. Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT). Herein, we hypothesi...

    Authors: Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:284

    Content type: Research article

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  6. Although stent retriever (SR) is recommended as a frontline device of endovascular treatment (EVT) for embolic large artery occlusion causing acute ischemic stroke, contact aspiration (CA) device showed simila...

    Authors: Joonsang Yoo, Seong-Joon Lee, Jeong-Ho Hong, Yong-Won Kim, Ji Man Hong, Chang-Hyun Kim, Dong-Hun Kang, Jin Wook Choi, Yong-Sun Kim, Sung-Il Sohn, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:283

    Content type: Research article

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  7. Ischemic stroke is a leading cause of morbidity and mortality. Thrombolytic therapy improves disability and survival rates; however, to be effective, it must be given within 4.5 h of onset. Moreover, thromboly...

    Authors: Jun Ni, Huisheng Chen, Guofang Chen, Yong Ji, Fei Yi, Zhuobo Zhang, Yi Yang, Jin Wu, Xueli Cai, Bei Shao, Jianfeng Wang, Yafang Liu, Deqin Geng, Xinhui Qu, Xiaohong Li, Yan Wei…

    Citation: BMC Neurology 2020 20:282

    Content type: Research article

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  8. Cerebral-cardiac syndrome, newly developed cardiac damage manifestations subsequent to cerebral injuries, is a common complication of stroke and leads to increased morbidity and mortality. The current study is...

    Authors: Haijuan Lian, Xiaomeng Xu, Xuhui Shen, Jinhua Chen, Dandan Mao, Yan Zhao and Meiqi Yao

    Citation: BMC Neurology 2020 20:272

    Content type: Research article

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  9. Cerebral vasospasm still results in high morbidity and mortality rates in patients after aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to establish a protocol for the management of vasosp...

    Authors: Chun-Ting Chen, Ching-Chang Chen, Alvin Yi-Chou Wang, Yi-Ming Wu, Shy-Chyi Chin, Po-Chuan Hsieh, Mun-Chun Yeap, Shih-Yuan Hsu and Ya-Jui Lin

    Citation: BMC Neurology 2020 20:271

    Content type: Research article

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  10. Stroke mimics account for up to one-third of acute stroke admissions and are a heterogeneous entity which pose diagnostic challenges. Diagnosing such patients is however crucial to avoid delays in treatment an...

    Authors: Sarah Shali Matuja, Khuzeima Khanbhai, Karim M. Mahawish and Patricia Munseri

    Citation: BMC Neurology 2020 20:270

    Content type: Research article

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  11. Acute ischemic stroke is a time-sensitive emergency where accurate diagnosis is required promptly. Due to time pressures, stroke mimics who present with similar signs and symptoms as acute ischemic stroke, pos...

    Authors: Tian Ming Tu, Guan Zhong Tan, Seyed Ehsan Saffari, Chee Keong Wee, David Jeremiah Ming Siang Chee, Camlyn Tan and Hoon Chin Lim

    Citation: BMC Neurology 2020 20:269

    Content type: Research article

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  12. Remote ischemic conditioning during cerebral ischemia (remote ischemic perconditioning, RIPerC) refers to the application of several cycles of brief ischemia and reperfusion (I/R) commonly to a limb, and it re...

    Authors: Francisco Purroy, Cristina García, Gerard Mauri, Cristina Pereira, Coral Torres, Daniel Vazquez-Justes, Mikel Vicente-Pascual, Ana Vena and Gloria Arque

    Citation: BMC Neurology 2020 20:266

    Content type: Research article

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  13. Level of dependency after a stroke is important for long-term outcome in several aspects, but less is known about important predictors for outcome depending on functional dependency. The aim of the current stu...

    Authors: Emma Westerlind, Daniel Hörsell and Hanna C. Persson

    Citation: BMC Neurology 2020 20:263

    Content type: Research article

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  14. Delayed cerebral ischemia is one of the leading causes of death and disability in patients with subarachnoid hemorrhage (SAH). Transluminal balloon angioplasty (TBA) is a therapeutic option for vasospasms affe...

    Authors: Ioannis Tsogkas, Vesna Malinova, Katharina Schregel, Dorothee Mielke, Daniel Behme, Veit Rohde, Michael Knauth and Marios-Nikos Psychogios

    Citation: BMC Neurology 2020 20:260

    Content type: Research article

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  15. Deep vein thrombosis (DVT) is an important complication of ischemic stroke, although the incidence of DVT is regarded as being lower in Asian than in non-Asian patients. Here, we investigated the incidence and...

    Authors: Sang Hee Ha, Yeon-Jung Kim, Sung Hyuk Heo, Dae-il Chang and Bum Joon Kim

    Citation: BMC Neurology 2020 20:257

    Content type: Research article

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  16. Stroke is a leading cause of long-term disability. Cost-effective post-stroke rehabilitation programs for upper limb are critically needed. Brain-Computer Interfaces (BCIs) which enable the modulation of Elect...

    Authors: Donatella Mattia, Floriana Pichiorri, Emma Colamarino, Marcella Masciullo, Giovanni Morone, Jlenia Toppi, Iolanda Pisotta, Federica Tamburella, Matteo Lorusso, Stefano Paolucci, Maria Puopolo, Febo Cincotti and Marco Molinari

    Citation: BMC Neurology 2020 20:254

    Content type: Study protocol

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  17. High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association...

    Authors: Pablo M. Lavados, Enrico Mazzon, Alexis Rojo, Alejandro M. Brunser and Verónica V. Olavarría

    Citation: BMC Neurology 2020 20:252

    Content type: Research article

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  18. The purpose of this study was to clarify the effect of asymmetric COW variants on carotid flow changes, and proposed an easy estimate of the representative carotid flow volume for accurate numerical simulation.

    Authors: Te-Chang Wu, Tai-Yuan Chen, Ching-Chung Ko, Jeon-Hor Chen and Ching-Po Lin

    Citation: BMC Neurology 2020 20:251

    Content type: Research article

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  19. Post-stroke depression (PSD) is a mood disorder characterized by depression and anhedonia caused by stroke. Metabolomics identified metabolites associated with PSD, but previous studies are based on gas chroma...

    Authors: Man Wang, Xianwei Gui, Lanxiang Wu, Sheng Tian, Hansen Wang, Liang Xie and Wei Wu

    Citation: BMC Neurology 2020 20:250

    Content type: Research article

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  20. Cerebral venous sinus thrombosis (CVST), a rare cause of cerebral infarction, is often unrecognized at initial presentation. We report the case of a patient with bilateral corpus callosum and corona radiata in...

    Authors: Rui Lan, Yun-zhi Ma, Xiao-ming Shen, Ji-tao Wu, Chun-qing Gu and Yong Zhang

    Citation: BMC Neurology 2020 20:249

    Content type: Case report

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  21. Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome for patients with acute ischemic stroke (AIS), but many of them still have substantial disability. Glibenclamide (US adopted n...

    Authors: Kaibin Huang, Zhong Ji, Yongming Wu, Yunqiang Huang, Guangning Li, Saijun Zhou, Zhi Yang, Wenguo Huang, Guoshuai Yang, Guohu Weng, Pingyan Chen and Suyue Pan

    Citation: BMC Neurology 2020 20:239

    Content type: Study protocol

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  22. Partially thrombosed giant aneurysms at the basilar apex (BA) artery are challenging lesions with a poor prognosis if left untreated. Here we describe a rare case of extensive brain edema after growth of a sur...

    Authors: Daniel García-Pérez, Irene Panero, Carla Eiriz, Luis Miguel Moreno, Pablo M. Munarriz, Igor Paredes, Alfonso Lagares and José F. Alén

    Citation: BMC Neurology 2020 20:232

    Content type: Case report

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  23. Arterial thoracic outlet syndrome is a rare condition characterized by a subclavian artery pathology associated with a bone abnormality. It is rarely associated with thromboembolic stroke. The mechanism of cer...

    Authors: Adam Celier, Simon Chabay, Aurélien Maurizot, Frédéric Cochennec, Daniela Stanciu and Fernando Pico

    Citation: BMC Neurology 2020 20:229

    Content type: Case report

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  24. New evidence on the efficacy and safety of dual antiplatelet therapy for secondary stroke prevention have been realized in the recent years. An updated meta analysis was done to determine the effect of the var...

    Authors: Christessa Emille Que Albay, Frederick Gavril D. Leyson and Federick C. Cheng

    Citation: BMC Neurology 2020 20:224

    Content type: Research article

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  25. Almost half of the stroke patients admitted to geriatric rehabilitation has persisting problems after discharge. Currently, there is no evidence based geriatric rehabilitation programme available for older str...

    Authors: Tom P. M. M. Vluggen, Jolanda C. M. van Haastregt, Jeanine A. Verbunt, Caroline M. van Heugten and Jos M. G. A. Schols

    Citation: BMC Neurology 2020 20:219

    Content type: Research article

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  26. Poststroke depression can lead to functional dependence, cognitive impairment and reduced quality of life. The aim of this study was to evaluate the effects of a percutaneous mastoid electrical stimulator (PME...

    Authors: Taoli Lu, Lanying He, Bei Zhang, Jian Wang, Lili Zhang, Wei Wei Dong and Hao Yang

    Citation: BMC Neurology 2020 20:217

    Content type: Research article

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  27. DL-3-n-butylphthalide (NBP) was demonstrated to increase the cerebral blood flow (CBF) in the animal models, but there are no clinic studies to verify this. We aimed to explore the effect of NBP on improving c...

    Authors: Dawei Chen, Yanwei Yin, Jin Shi, Fen Yang, Kehua Wang, Faguo Zhao, Wenping Li and Bin Li

    Citation: BMC Neurology 2020 20:212

    Content type: Research article

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  28. Vestibular migraine, a kind of acute vestibular syndrome, leads to both migraines and vertigo symptoms in a single patient. The occurrence of vestibular migraine has shown an obvious increase in female groups ...

    Authors: Ying Xin, Junyi Fu, Longchang Xie, Jie Yang and Guanhao Ke

    Citation: BMC Neurology 2020 20:211

    Content type: Case report

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  29. Stroke burden in young adults is growing associated with unique risk factors and devastating outcomes. We aimed to investigate the magnitude, risk factors and outcomes of first ever stroke in young adults ≤45 ...

    Authors: Sarah Shali Matuja, Patricia Munseri and Khuzeima Khanbhai

    Citation: BMC Neurology 2020 20:206

    Content type: Research article

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  30. Direct evidence of intimal flaps, double lumen and intramural haematomas (IMH) is difficult to detect on conventional angiography in most intracranial vertebrobasilar dissecting aneurysms (VBDAs). Our purpose ...

    Authors: Xianjin Zhu, Hancheng Qiu, Ferdinand K. Hui, Yiqun Zhang, Yun-e Liu, Fengyuan Man and Wei-Jian Jiang

    Citation: BMC Neurology 2020 20:199

    Content type: Research article

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  31. Acute ischemic stroke attack with and without a recent TIA may differ in clinical risk factors, and this may affect treatment outcomes following thrombolytic therapy. We examined whether the odds of exclusion ...

    Authors: Nicolas Poupore, Dan Strat, Tristan Mackey, Ashley Snell and Thomas Nathaniel

    Citation: BMC Neurology 2020 20:197

    Content type: Research article

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  32. Endovascular therapy (EVT) is increasingly used to improve cerebral reperfusion after moderate-to-severe acute ischemic stroke (AIS). However, the influence of hemodynamic factors on clinical outcome is still ...

    Authors: Ge Tian, Zhong Ji, Kaibin Huang, Zhenzhou Lin, Suyue Pan and Yongming Wu

    Citation: BMC Neurology 2020 20:189

    Content type: Research article

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  33. Recovery patterns of motor function and activity capacity of the upper extremity after stroke have been described, but less is known about longitudinal changes of perceived manual activity performance. The aim...

    Authors: Elisabeth Ekstrand, Katharina S. Sunnerhagen, Hanna C. Persson, Åsa Lundgren-Nilsson and Margit Alt Murphy

    Citation: BMC Neurology 2020 20:181

    Content type: Research article

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  34. The etiologic determinants of cryptogenic stroke remain a diagnostic challenge in clinical practice. Fabry disease (FD) is one of the monogenic causes of stroke that may remain unrecognized as a potential cont...

    Authors: Shuai Jiang, Lei Wang, Yuying Yan, Qiange Zhu, Jincheng Wan, Jiayu Sun and Bo Wu

    Citation: BMC Neurology 2020 20:180

    Content type: Case report

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  35. Cognitive impairment (CI) with mixed vascular and neurodegenerative pathologies after stroke is common. The role of amyloid pathology in post-stroke CI is unclear. We hypothesize that amyloid deposition, measu...

    Authors: Guri Hagberg, Hege Ihle-Hansen, Brynjar Fure, Bente Thommessen, Håkon Ihle-Hansen, Anne Rita Øksengård, Mona K. Beyer, Torgeir B. Wyller, Ebba Gløersen Müller, Sarah T. Pendlebury and Per Selnes

    Citation: BMC Neurology 2020 20:174

    Content type: Research article

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  36. Insufficient amounts of physical activity is a risk factor for (recurrent) stroke. People with a stroke or transient ischemic attack (TIA) have a high risk of recurrent stroke and have lower levels of physical...

    Authors: Wendy Hendrickx, Lara Vlietstra, Karin Valkenet, Roderick Wondergem, Cindy Veenhof, Coralie English and Martijn Frits Pisters

    Citation: BMC Neurology 2020 20:168

    Content type: Research article

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  37. Stroke-like episodes (SLEs) in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) with m.3243A > G mutation usually develop in the cerebral cortex. Few reports have docum...

    Authors: Munenori Oyama, Takahiro Iizuka, Jin Nakahara and Yoshikane Izawa

    Citation: BMC Neurology 2020 20:167

    Content type: Case report

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  38. Early neurological deterioration (END) is common in acute ischemic stroke (IS). However, the underlying mechanisms for END are unclear. The aim of this study was to evaluate the associations of 16 variants in ...

    Authors: Xingyang Yi, Qiang Zhou, Yongyin Zhang, Ju Zhou and Jing Lin

    Citation: BMC Neurology 2020 20:159

    Content type: Research article

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  39. Dysphagia is common after stroke. Patients with dysphagia have a higher risk of stroke-associated pneumonia (SAP) and poor outcomes. Early detection of dysphagia is necessary to identify and manage patients at...

    Authors: Zhu-Yun Liu, Xiao-Pei Zhang, Miao-Miao Mo, Ri-Chun Ye, Cai-Xia Hu, Min-Qing Jiang and Man-Qiu Lin

    Citation: BMC Neurology 2020 20:154

    Content type: Research article

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  40. Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able ...

    Authors: Shengde Li, Li-Ying Cui, Craig Anderson, Chunpeng Gao, Chengdong Yu, Guangliang Shan, Longde Wang and Bin Peng

    Citation: BMC Neurology 2020 20:147

    Content type: Research article

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  41. Endovascular therapy is widely used in acute large vessel occlusion. This study investigated whether imaging of lateral lenticulostriate arteries (LSAs) before thrombectomy would potentially be helpful for pre...

    Authors: Feifeng Liu, Chen Chen, Lan Hong, Hao Shen, Wenjie Cao, Qiang Dong, Xinyi Yang, Mengruo Guo, Ying Li, Yaping Xiao, Xin Cheng and Gang Li

    Citation: BMC Neurology 2020 20:139

    Content type: Research article

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  42. Following acute ischemic stroke (AIS), approximately half of patients do not achieve recanalization after intravenous administration of tissue plasminogen activator (rt-PA). Thrombolysis resistance is a possib...

    Authors: Ye Li, Heying Wang, Lili Zhao, Yating Jian, Meijuan Dang, Yu Jiang, Yiheng Zhang, Lei Zhang, Huqing Wang, Ru Zhang, Mingxia Chen and Guilian Zhang

    Citation: BMC Neurology 2020 20:135

    Content type: Case report

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  43. For acute ischemic stroke (AIS) patient receiving mechanical thrombectomy (MT), renal dysfunction was an independent risk factor of contrast-induced nephropathy which may affect clinical outcomes. However, the...

    Authors: Xiding Pan, Feng Zhou, Rui Shen, Yubing Zhu, Hisatomi Arima, Jie Yang and Junshan Zhou

    Citation: BMC Neurology 2020 20:134

    Content type: Research article

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  44. Cavernous malformations are rare cerebral pseudo-vascular lesions with annualized bleeding rates of 0.5–3% in most studies. Of the various explored risk factors for bleeding to date, only prior hemorrhage has ...

    Authors: Benjamin R. Hartley, Corinne Birnbaum and Caitlin E. Hoffman

    Citation: BMC Neurology 2020 20:131

    Content type: Case report

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  45. Hyperhomocysteinemia (HHCY) is a risk factor for cardiovascular and cerebrovascular diseases. The C677T 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism increases homocysteine (HCY) levels. ...

    Authors: Xiaoxia Du, Lin Xiao, Rong Sun, Kunpeng Li, Lin Liang, Luping Song and Zhizhong Liu

    Citation: BMC Neurology 2020 20:128

    Content type: Research article

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  46. The modified Rankin Scale (mRS) is a key global outcome measure after stroke internationally. The latest English version of the simplified modified Rankin scale questionnaire (smRSq)(2011) is a reliable and va...

    Authors: Junliang Yuan, Yunxiao Wang, Wenli Hu and Askiel Bruno

    Citation: BMC Neurology 2020 20:127

    Content type: Research article

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