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Cerebrovascular disease and stroke

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Spinal AVF (SAVF), a potentially treatable cause of myelopathy, remains a challenging diagnosis. Its rarity and non-specific imaging findings often result in misdiagnosis despite a high index of clinical suspi...

    Authors: D. Krishnan, S. Viswanathan, N. Rose, H. S. N. Benjamin, A. M. Ong and F. L. Hiew

    Citation: BMC Neurology 2021 21:366

    Content type: Case report

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  2. Limited data are available for evaluating the relationship between the prognosis and body temperature (BT) in patients treated with mechanical thrombectomy (MT), especially in those with successful recanalizat...

    Authors: Man Chen, Jinghuan Fang, Xintong Wu, Qin Liu, Ling Feng and Li He

    Citation: BMC Neurology 2021 21:365

    Content type: Research article

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  3. Few studies have investigated the influence of white matter lesions (WMLs) on the prognosis of acute cardioembolic stroke (CES). We aimed to explore the role of WMLs in predicting 3-month prognosis of CES with...

    Authors: Yikun Guo, Zhuoyou Chen, Qian Wang, Min Zhang, Guanzhong Dong, Wenying Zou, Tian Yao and Yun Xu

    Citation: BMC Neurology 2021 21:364

    Content type: Research article

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  4. Occlusion of the internal carotid artery (ICA), whether isolated or in the setting of a tandem lesion (TL) have a poor response to treatment with intravenous thrombolysis. Previous studies ​​have demonstrated ...

    Authors: Luigi Cirillo, Daniele Giuseppe Romano, Gianfranco Vornetti, Giulia Frauenfelder, Chiara Tamburrano, Francesco Taglialatela, Salvatore Isceri, Renato Saponiero, Rosa Napoletano, Mauro Gentile, Michele Romoli, Ciro Princiotta, Luigi Simonetti and Andrea Zini

    Citation: BMC Neurology 2021 21:362

    Content type: Research article

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  5. Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary ed...

    Authors: Xue-Bing Chen, Dong Qu, Qing Zhang, Xia Yue and Dong-Fang Qiao

    Citation: BMC Neurology 2021 21:346

    Content type: Case report

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  6. Resection of cerebral arteriovenous malformations (AVM) is technically demanding because of size, eloquent location or diffuse nidus. Controlled arterial hypotension (CAH) could facilitate haemostasis. We perf...

    Authors: Katharina Riedel, Marcus Thudium, Azize Boström, Johannes Schramm and Martin Soehle

    Citation: BMC Neurology 2021 21:339

    Content type: Research article

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  7. The cerebellum receives afferent signals from spinocerebellar pathways regulating lower limb movements. However, the longitudinal changes in the spinocerebellar pathway in the early stage of unilateral suprate...

    Authors: Gang Liu, Yaomin Guo, Chao Dang, Kangqiang Peng, Shuangquan Tan, Chuanmiao Xie, Shihui Xing and Jinsheng Zeng

    Citation: BMC Neurology 2021 21:320

    Content type: Research article

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  8. Antiplatelet drugs may prevent recurrent ischemic events after ischemic stroke but their relative effectiveness and harms still need to be clarified. Within this network meta-analysis we aimed to summarize the...

    Authors: Cinzia Del Giovane, Giorgio B. Boncoraglio, Lorenza Bertù, Rita Banzi and Irene Tramacere

    Citation: BMC Neurology 2021 21:319

    Content type: Research article

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  9. Levels of self-reported health do not always correlate with levels of physical disability in stroke survivors. We aimed to explore what underlies the difference between subjective self-reported health and obje...

    Authors: Nahal Mavaddat, Euan Sadler, Lisa Lim, Kate Williams, Elizabeth Warburton, Ann Louise Kinmonth, Chris Mckevitt and Jonathan Mant

    Citation: BMC Neurology 2021 21:315

    Content type: Research article

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  10. Extracranial carotid artery disease is considered a risk factor for developing acute cerebrovascular diseases. The paper suggests the “Stroke-Stop” formula as hypothesis for the determination of the risk of de...

    Authors: Іvan Kopolovets, Peter Berek, Peter Stefanic, Dmytro Lotnyk, Rastislav Mucha, Zdenka Hertelyova, Stefan Toth, Nadiya Boyko and Vladimir Sihotsky

    Citation: BMC Neurology 2021 21:310

    Content type: Research article

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  11. To summarize the safety and effectiveness of high flow extracranial to intracranial saphenous vein bypass grafting in the treatment of complex intracranial aneurysms.

    Authors: Jibo Zhang, Yu Feng, Wenyuan Zhao, Kui Liu and Jincao Chen

    Citation: BMC Neurology 2021 21:307

    Content type: Technical advance

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  12. The precise etiology of anterior inferior cerebellar artery (AICA) infarction is difficult to identify because of the high anatomic variability of vertebrobasilar arteries and the limitations of conventional v...

    Authors: Zhi-yong Zhang, Zhi Zhou, Hai-bo Zhang and Jin-song Jiao

    Citation: BMC Neurology 2021 21:299

    Content type: Case report

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  13. Ischemic stroke, including transient ischemic attack (TIA) and acute-phase cerebral infarction (aCI), is a serious health problem in the aging society. Thus, this study aimed to identify TIA and aCI biomarkers.

    Authors: Hao Wang, Hao Lu, Xiao-Meng Zhang, Ken-ichiro Goto, Eiichi Kobayashi, Yoichi Yoshida, Akihiko Adachi, Tomoo Matsutani, Yasuo Iwadate, Seiichiro Mine, Toshio Machida, Mizuki Sata, Kazumasa Yamagishi, Hiroyasu Iso, Norie Sawada, Shoichiro Tsugane…

    Citation: BMC Neurology 2021 21:274

    Content type: Research article

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  14. In neurosurgery, it is important to use local hemostatic agents. We have explored a more powerful method of hemostasis by the combination of commercially available hemostatic agents with fibrin glue in the hop...

    Authors: Katsumi Takizawa, Daiki Okazaki, Yoshitaka Takegawa, Yuki Koga, Masataka Sagata, Kenichi Michishita and Noriko Shinya

    Citation: BMC Neurology 2021 21:270

    Content type: Research article

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  15. Transient global amnesia (TGA) is a clinical syndrome characterized by a temporary short-term memory loss with inability to retain new memories, usually lasting 2 to 8 h. TGA may be related to several medical ...

    Authors: Sabrina Ravaglia, Antonio Zito, Lara Ahmad and Isabella Canavero

    Citation: BMC Neurology 2021 21:266

    Content type: Case report

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  16. Fatigue and sleep disturbance are debilitating problems following brain injury and there are no established treatments. Building on demonstrated efficacy of blue light delivered via a lightbox in reducing fati...

    Authors: Laura J. Connolly, Shantha M. W. Rajaratnam, Jade M. Murray, Gershon Spitz, Steven W. Lockley and Jennie L. Ponsford

    Citation: BMC Neurology 2021 21:262

    Content type: Research article

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  17. Dual antiplatelet therapy (DAPT) is necessary for stent assisted coiling. However, long term use of DAPT has a potential risk of hemorrhagic events. We aimed to examine the relationship between clopidogrel rea...

    Authors: Kenji Shoda, Yukiko Enomoto, Yusuke Egashira, Takamasa Kinoshita, Daisuke Mizutani and Toru Iwama

    Citation: BMC Neurology 2021 21:247

    Content type: Research article

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  18. Studies have suggested that glycoprotein IIb/IIIa antagonists such as tirofiban are beneficial for patients with acute coronary syndromes. However, it is still uncertain about the efficacy and safety of tirofi...

    Authors: Chunrong Tao, Yuyou Zhu, Chao Zhang, Jianlong Song, Tianlong Liu, Xiaodong Yuan, Wenwu Luo, Changchun Chen, Dezhi Liu, Yuanyuan Zhu, Jie Liu and Wei Hu

    Citation: BMC Neurology 2021 21:237

    Content type: Research article

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  19. Dynamic axial computed tomographic angiography (dynax–CTA), covering a thin width, with a focus on the bilateral middle cerebral artery (MCA), can quickly visualize the internal carotid artery (ICA) or MCA occ...

    Authors: Takahisa Mori, Kazuhiro Yoshioka, Wataru Mori and Yuhei Tanno

    Citation: BMC Neurology 2021 21:230

    Content type: Research article

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  20. Ischemic events are the most common postoperative complication in bypass surgery for moyamoya disease (MMD), but the risk factors for pediatric MMD remain unclear. The goal of the study was to investigate the ...

    Authors: Xiaofeng Deng, Peicong Ge, Rong Wang, Dong Zhang, Jizong Zhao and Yan Zhang

    Citation: BMC Neurology 2021 21:229

    Content type: Research article

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  21. Presentation with massive systemic embolization as the initial manifestation of occult malignancy is infrequent. The standard management of cancer-related arterial thromboembolism has not yet been established.

    Authors: Zheng Wang, Jiangyong Miao, Lina Wang, Ying Liu, Hui Ji, Xiangjian Zhang and Lili Cui

    Citation: BMC Neurology 2021 21:221

    Content type: Case report

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  22. Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy. Its typical neuroimaging features are punctate white matter lesio...

    Authors: Yuying Yan, Shuai Jiang, Ruilin Wang, Xiang Wang, Peng Li and Bo Wu

    Citation: BMC Neurology 2021 21:219

    Content type: Case report

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  23. Chronic inflamed tissue in nasal cavity is a rare complication of transsphenoidal approach (TSA). Inflamed tissue is rich in blood vessels, which can lead to frequent nosebleeds. In addition, chronic inflammat...

    Authors: Ja Yoon Kim, Yong Bae Kim and Joonho Chung

    Citation: BMC Neurology 2021 21:215

    Content type: Case report

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  24. Heterogenous central nervous system (CNS) neurologic manifestations of polyarteritis nodosa (PAN) are underrecognized. We review three cases of patients with PAN that illustrate a range of nervous system patho...

    Authors: Cathra Halabi, Erika K. Williams, Ramin A. Morshed, Mauro Caffarelli, Christine Anastasiou, Tarik Tihan, Daniel Cooke, Adib A. Abla, Christopher F. Dowd, Vinil Shah, Sharon Chung and Megan B. Richie

    Citation: BMC Neurology 2021 21:205

    Content type: Case report

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  25. Since the nineteenth century, a great variety of crossed brainstem syndromes (CBS) have been described in the medical literature. A CBS typically combines ipsilateral cranial nerves deficits to contralateral l...

    Authors: Nathan Beucler, Sébastien Boissonneau, Aurélia Ruf, Stéphane Fuentes, Romain Carron and Henry Dufour

    Citation: BMC Neurology 2021 21:204

    Content type: Case report

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  26. The Low-profile Visualized Intraluminal Support (LVIS) device is a self-expanding, nitinol, single-braid, closed-cell device that was recently developed for endovascular embolization of intracranial aneurysms....

    Authors: Quanlong Hong, Wenqiang Li, Jing Ma, Peng Jiang and Yisen Zhang

    Citation: BMC Neurology 2021 21:198

    Content type: Research article

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  27. Abnormal hypoperfusion on the surgical side after carotid artery stenting is rare. Neurological deterioration caused by it is deceptive, which can easily lead to misdiagnosis. The mechanism of hypoperfusion ha...

    Authors: Zhizhong Yan, Zhonghua Shi, Yuhai Wang, Chunlei Zhang, Huize Liu, Jin Cai and Xin Zhang

    Citation: BMC Neurology 2021 21:188

    Content type: Case report

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  28. An important cause of hemisensory syndrome is ischemic stroke. However, the diagnostic yield of neuroradiological imaging on hemisensory syndrome is low. Therefore, we aim to describe patients hospitalized wit...

    Authors: Pei Xuan Koh, Joanna Ti, Seyed Ehsan Saffari, Zhen Yu Isis Claire Lim and Tianming Tu

    Citation: BMC Neurology 2021 21:179

    Content type: Research article

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  29. The physiological and pathological significance of the arachnoid membrane (AM) is still unknown. In this study, we investigated various characteristics of the AM, focusing on the influence of inflammation and ...

    Authors: Hime Suzuki, Takeshi Mikami, Naotoshi Iwahara, Yukinori Akiyama, Masahiko Wanibuchi, Katsuya Komatsu, Rintaro Yokoyama, Tsukasa Hirano, Ryusuke Hosoda, Yoshiyuki Horio, Atsushi Kuno and Nobuhiro Mikuni

    Citation: BMC Neurology 2021 21:169

    Content type: Research article

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  30. We report on a patient with an intracerebral hemorrhage (ICH), who showed delayed development of aphasia, which was demonstrated via follow up diffusion tensor tractography (DTT) to be related to neural degene...

    Authors: Min Jye Cho and Sung Ho Jang

    Citation: BMC Neurology 2021 21:166

    Content type: Case report

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  31. Patients who have been successfully treated for an aneurysmal subarachnoid hemorrhage (aSAH) often retain multiple health complaints, including mood disorders, cognitive complaints, fatigue, and problems with ...

    Authors: Edith Nobels-Janssen, Inger L. Abma, Wim I. M. Verhagen, Ronald H. M. A. Bartels, Philip J. van der Wees and Jeroen D. Boogaarts

    Citation: BMC Neurology 2021 21:162

    Content type: Research article

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  32. The initial CT blend sign is an imaging marker that has been used to predict haematoma expansion and poor outcomes in patients with small-volume intracerebral haemorrhage (ICH). However, the association of the...

    Authors: Xu Yang, Yan Zhu, Linshan Zhang, Likun Wang, Yuanhong Mao, Yinghui Li, Jinbiao Luo and Guofeng Wu

    Citation: BMC Neurology 2021 21:160

    Content type: Research article

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  33. Stroke incidence is reportedly increasing in younger populations, although the reasons for this are not clear. We explored possible reasons by quantifying trends in neurologically focused emergency department ...

    Authors: Abhinav J. Appukutty, Lesli E. Skolarus, Mellanie V. Springer, William J. Meurer and James F. Burke

    Citation: BMC Neurology 2021 21:152

    Content type: Research article

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  34. The onset time of intracerebral hemorrhage (ICH) may be closely related to the working style and living habits of people, which are determined by different income sources in China. Therefore, the purpose of ou...

    Authors: Yan-Yue Wang, Ning Yan, En-Yuan Wang and Yun-Tao Pu

    Citation: BMC Neurology 2021 21:140

    Content type: Research article

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  35. Pneumonia is related to poor prognosis in acute ischemic stroke (AIS), and its risk might be higher in atrial fibrillation (AF) related AIS with elevated plasma D-dimer. The aim of our study was to investigate...

    Authors: Xu Yang, Taoli Lu, Zhanli Qu, Yi Zhang, Pingping Liu and Ying Ma

    Citation: BMC Neurology 2021 21:137

    Content type: Research article

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  36. Stroke is a leading cause of disability worldwide and the cardiovascular fitness levels of stroke survivors are diminished to an extent that impairs functioning and activities of daily living performance. Whil...

    Authors: Hanna Reynolds, Sarah Steinfort, Jane Tillyard, Sarah Ellis, Alan Hayes, Erik D. Hanson, Tissa Wijeratne and Elizabeth H. Skinner

    Citation: BMC Neurology 2021 21:132

    Content type: Research article

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  37. The computed tomography angiography (CTA) spot sign is a validated predictor of hematoma expansion and 30-day mortality in intracerebral hemorrhage (ICH). However, whether the spot sign predicts worse function...

    Authors: Wen-Che Tseng, Yu-Fen Wang, Tyng-Guey Wang and Ming-Yen Hsiao

    Citation: BMC Neurology 2021 21:131

    Content type: Research article

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  38. Although increasing evidence showed the correlations between white matter hyperintensities (WMHs) and cognitive impairment, the relationship between them is still modest. Many researchers began to focus on the...

    Authors: Zhi-gang Min, Hai-rong Shan, Long Xu, Dai-hai Yuan, Xue-xia Sheng, Wen-chao Xie, Ming Zhang, Chen Niu, Tahir Mehmood Shakir and Zhi-hong Cao

    Citation: BMC Neurology 2021 21:128

    Content type: Research article

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