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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Content type: Case report

    Due to improvements in both the quality and availability of intracranial imaging as well as the evolution of surgical and endovascular techniques during the last decade, the number of treatments of unruptured ...

    Authors: Christin Campe, Jens Neumann, I. Erol Sandalcioglu, Ali Rashidi and Michael Luchtmann

    Citation: BMC Neurology 2019 19:226

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  2. Content type: Research article

    Self-rated health (SRH) allows for comparison and identification of the health status of various populations. The aim of this study was to conduct a systematic review of the literature to expand the understand...

    Authors: Érika de Freitas Araújo, Ramon Távora Viana, Luci Fuscaldi Teixeira-Salmela, Lidiane Andrea Oliveira Lima and Christina Danielli Coelho de Morais Faria

    Citation: BMC Neurology 2019 19:221

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  3. Content type: Research article

    Stroke patients are often affected by long-term disabilities with needs concerning social issues. There is relatively little consideration of social recovery of patients and the support required to return to w...

    Authors: Sophie Lehnerer, Benjamin Hotter, Inken Padberg, Petra Knispel, Dike Remstedt, Andrea Liebenau, Ulrike Grittner, Ian Wellwood and Andreas Meisel

    Citation: BMC Neurology 2019 19:220

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  4. Content type: Research article

    The global burden of stroke epidemiology is changing rapidly. Over the 1990–2013 periods, there was a significant increase in the absolute number of deaths and incident events of stroke. The burden of stroke v...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:213

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  5. Content type: Research article

    Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei pro...

    Authors: Yanfeng Zhou, Shijiao Yan, Xingyue Song, Yanhong Gong, Wenzhen Li, Mengdie Wang, Xiaoxv Yin, Bo Hu and Zuxun Lu

    Citation: BMC Neurology 2019 19:202

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  6. Content type: Research article

    Mechanical thrombectomy (MT) using stent retriever assisted vacuum-locked extraction (SAVE) is a promising method for anterior circulation strokes. We present our experience with SAVE for large vessel occlusio...

    Authors: Volker Maus, Hanna Styczen, Jan Liman, Ilko Maier, Alex Brehm, Ioannis Tsogkas and Marios-Nikos Psychogios

    Citation: BMC Neurology 2019 19:197

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  7. Content type: Study protocol

    Recovery of upper limb function in individuals after a stroke remains challenging. Modified constraint-induced movement therapy (m-CIMT) has strong evidence for increasing the use and recovery of sensorimotor ...

    Authors: Erika Shirley Moreira da Silva, Gabriela Lopes Santos, Aparecida Maria Catai, Alexandra Borstad, Natália Pereira Duarte Furtado, Isabela Arruda Verzola Aniceto and Thiago Luiz Russo

    Citation: BMC Neurology 2019 19:196

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    The Correction to this article has been published in BMC Neurology 2019 19:225

  8. Content type: Case report

    Emotional processes and responses are underestimated in stroke patients because the massive clinical picture of large hemispheric strokes often hides these symptoms. We report on a patient with peculiar unplea...

    Authors: Mariagiovanna Cantone, Giuseppe Lanza, Rita Bella, Giovanni Pennisi, Paola Santalucia, Placido Bramanti and Manuela Pennisi

    Citation: BMC Neurology 2019 19:193

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  9. Content type: Research article

    The topographic location of acute pontine infarction is associated with clinical syndromes and prognosis. Previous studies focused on isolated pontine infarction, but the topographic location of unisolated pon...

    Authors: Jiehong Huang, Zhihua Qiu, Piansi Zhou, Jianming Li, Yingxin Chen, Ruiyun Huang, Chujing Li, Xilin Ouyang, Huazhuo Feng, Hanqing Xu, Dezhi Liu, Zheng Dai, Juehua Zhu, Xinfeng Liu, Hongbing Chen and Yongjun Jiang

    Citation: BMC Neurology 2019 19:186

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  10. Content type: Research article

    Stroke is the second-leading global cause of death behind heart disease in 2013 and is a major cause of permanent disability. The burden of stroke in terms of mortality, morbidity and disability is increasing ...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:183

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  11. Content type: Case report

    Hypothalamic lesions, such as tumors and demyelinating diseases, reportedly cause abnormal sleepiness. However, stroke involving the hypothalamus has rarely been described. Here, we report a patient with infar...

    Authors: Takeo Matsubara, Keisuke Suzuki, Akiko Kawasaki, Masayuki Miyamoto, Madoka Okamura, Takashi Kanbayashi, Hidehiro Takekawa, Toshiki Nakamura, Yuji Watanabe, Masanori Matsubara and Koichi Hirata

    Citation: BMC Neurology 2019 19:182

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  12. Content type: Research article

    Optimizing thrombolytic therapy is vital for improving stroke outcomes. We aimed to develop standardized thrombolysis conditions to evaluate the efficacy of tenecteplase (TNK) compared to the current gold stan...

    Authors: Tobias Frühwald, Ulrich Gärtner, Nils Stöckmann, Jan-Henning Marxsen, Carolin Gramsch and Florian C. Roessler

    Citation: BMC Neurology 2019 19:181

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  13. Content type: Research article

    This study examined how intracranial large artery stenosis (ILAS), symptomatic and asymptomatic ILAS, and risk factors affect unfavorable outcome events after medical treatment in routine clinical practice.

    Authors: K. C. Chang, I. C. Chuang, Y. C. Huang, C. Y. Wu, W. C. Lin, Y. L. Kuo, T. H. Lee and S. J. Ryu

    Citation: BMC Neurology 2019 19:180

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  14. Content type: Research article

    B-mode and Color Doppler ultrasonography (CDUS) are the methods of choice for screening and determining the degree of Carotid artery stenosis. The evaluation of stenosis with calcification may be hampered by a...

    Authors: Estelle E. Seyman, Natan Bornstein, Eitan Auriel, Oren Cohen, Tania Nissel and Hen Hallevi

    Citation: BMC Neurology 2019 19:178

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  15. Content type: Research article

    Insulin resistance (IR) in relation to diabetes is a risk factor for ischemic stroke (IS), whereas less is known about non-diabetic IR and outcome after IS.

    Authors: Daniel Åberg, N. David Åberg, Katarina Jood, Lukas Holmegaard, Petra Redfors, Christian Blomstrand, Jörgen Isgaard, Christina Jern and Johan Svensson

    Citation: BMC Neurology 2019 19:177

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  16. Content type: Research article

    Elevated levels of plasma D-dimer increase the risk of ischemic stroke, stroke severity, and the progression of stroke status, but the association between plasma D-dimer level and functional outcome is unclear...

    Authors: Tao Yao, Bo-Lin Tian, Gang Li, Qin Cui, Cui-fang Wang, Qi Zhang, Bo Peng, Yan Gao, Yan-Qiang Zhan, Dan Hu, Lu Xu and Gao-Hua Wang

    Citation: BMC Neurology 2019 19:175

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  17. Content type: Research article

    The exact relationship between 25-hydroxyvitamin D [25(OH) D] levels and small vessel disease (SVD) are not clear in China. The aim of this study was to determine such the association between 25(OH) D and SVD ...

    Authors: Junzeng Si, Kuibao Li, Peiyan Shan and Junliang Yuan

    Citation: BMC Neurology 2019 19:164

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  18. Content type: Research article

    Patients with vertebrobasilar dolichoectasia usually have persistent hemodynamic abnormalities, and therefore, may bear an increased risk of stroke. This study aimed to identify risk factors for stroke recurre...

    Authors: Zhaoyao Chen, Shuai Zhang, Zhengze Dai, Xi Cheng, Minghua Wu, Qiliang Dai, Xinfeng Liu and Gelin Xu

    Citation: BMC Neurology 2019 19:163

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  19. Content type: Research article

    Intravenous thrombolysis has been recently introduced in Nepal for the management of acute ischemic stroke. Pre-hospital delay is one of the main reasons that hinder thrombolytic therapy. The objective of this...

    Authors: Gaurav Nepal, Jayant Kumar Yadav, Babin Basnet, Tirtha Man Shrestha, Ghanshyam Kharel and Rajeev Ojha

    Citation: BMC Neurology 2019 19:155

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  20. Content type: Case report

    Simultaneous cerebral and myocardial infarction is called cardiocerebral infarction (CCI), and is rarely encountered. Because of the narrow time window and complex pathophysiology, CCI is challenging to immedi...

    Authors: Soichiro Abe, Kanta Tanaka, Hiroshi Yamagami, Kazutaka Sonoda, Hiroya Hayashi, Shuichi Yoneda, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2019 19:152

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  21. Content type: Research article

    This study aimed to investigate the cerebral blood flow (CBF) and frontal lobe cognitive function in severe internal carotid artery (ICA) stenosis patients with different types of collateral circulation.

    Authors: Wei Wei, Xingyang Yi, Jianghai Ruan, Xiaodong Duan, Hua Luo and Zhiyu Lv

    Citation: BMC Neurology 2019 19:151

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  22. Content type: Research article

    Mechanical thrombectomy has been proven as a standard care for moderate to severe ischemic stroke with anterior large vessel occlusion (LVO); however, whether it is equally effective in mild ischemic stroke (M...

    Authors: Xian-Jin Shang, Zhong-Hua Shi, Cai-Feng He, Shuai Zhang, Yong-Jie Bai, Yong-Tao Guo, Bo Sun, Shun Li, Huai-Ming Wang, Zhi-Ming Zhou, Wen-Jie Zi and Xin-Feng Liu

    Citation: BMC Neurology 2019 19:150

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  23. Content type: Research article

    Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are c...

    Authors: A. Mengel, L. Ulm, B. Hotter, H. Harms, S. K. Piper, U. Grittner, J. Montaner, C. Meisel, A. Meisel and S. Hoffmann

    Citation: BMC Neurology 2019 19:148

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  24. Content type: Research article

    Triglycerides (TG)/high-density lipoprotein (HDL) cholesterol ratio is a marker of small/dense low-density lipoprotein particles, which are closely associated with various metabolic and vascular diseases. Howe...

    Authors: Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Hyuktae Kwon and Su-Min Jeong

    Citation: BMC Neurology 2019 19:147

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  25. Content type: Case report

    Heat stroke (HS) is a critical illness that can cause multiple organ dysfunction, including damage to the central nervous system (CNS), which can be life-threatening in severe cases. Brain lesions in patients ...

    Authors: Lizhi Cao, Juan Wang, Yaxuan Gao, Yumei Liang, Jinhua Yan, Yunhai Zhang, Mingqin Zhu, Tianfei Luo and Jiafeng Chen

    Citation: BMC Neurology 2019 19:133

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  26. Content type: Research article

    Mood disorder after stroke is common but drug and psychosocial treatments have been assessed with disappointing results. Preventing mood disorder from developing in the first place could be a better approach a...

    Authors: Kate Hill, Allan House, Peter Knapp, Carrie Wardhaugh, John Bamford and Andy Vail

    Citation: BMC Neurology 2019 19:128

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  27. Content type: Research article

    Immune cells are involved in all stages of acute ischaemic stroke (AIS) and possess both neuroprotective and neurodamaging properties. It has been suggested that immune system activation after stroke may be as...

    Authors: Neringa Jucevičiūtė, Paulius Mikužis and Renata Balnytė

    Citation: BMC Neurology 2019 19:127

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  28. Content type: Case report

    Fabry disease is rare, and the diagnosis is often delayed. Here, we describe a case of Fabry disease resulting in vasculopathy of the central nervous system. Magnetic resonance (MR) black-blood sequence (three...

    Authors: De-Zheng Kong, Ya-Hui Lian, Lin-Jing Wang, Chun-Mei Wang, Yang-Yang Meng and Hong-Wei Zhou

    Citation: BMC Neurology 2019 19:115

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  29. Content type: Case report

    Internal jugular vein stenosis (IJVS), characterized by a series of clinical manifestations, such as head and neck symptoms, visual and ear symptoms, as well as sleep disorder, has been receiving attention in ...

    Authors: Min Li, Yuan Sun, Chong Ching Chan, Chunqiu Fan, Xunming Ji and Ran Meng

    Citation: BMC Neurology 2019 19:112

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  30. Content type: Research article

    endovascular therapy (ET) is the standard of care for anterior circulation acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). The role of adjunctive intravenous thrombolysis (IVT) in these pat...

    Authors: Massimo Gamba, Nicola Gilberti, Enrico Premi, Angelo Costa, Michele Frigerio, Dikran Mardighian, Veronica Vergani, Raffaella Spezi, Ilenia Delrio, Andrea Morotti, Loris Poli, Valeria De Giuli, Filomena Caria, Alessandro Pezzini, Roberto Gasparotti, Alessandro Padovani…

    Citation: BMC Neurology 2019 19:103

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  31. Content type: Research article

    Exercise has failed to reduce falls in those with chronic stroke. A limitation of traditional exercise is that the motor responses needed to prevent a fall are not elicited (i.e. they lack processing specificity)...

    Authors: Jamie Pigman, Darcy S. Reisman, Ryan T. Pohlig, Tamara R. Wright and Jeremy R. Crenshaw

    Citation: BMC Neurology 2019 19:102

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  32. Content type: Research article

    A revised classification of cerebellar infarctions (CI) may uncover unrecognized associations with etiologic stroke subtypes. We hypothesized that obliquely oriented small cortical cerebellar infarction (SCCI)...

    Authors: Adrien Ter Schiphorst, Lavinia Tatu, Vincent Thijs, Christophe Demattei, Eric Thouvenot and Dimitri Renard

    Citation: BMC Neurology 2019 19:100

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  33. Content type: Case report

    Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare clinical entity, characterized by headaches, seizures, rapidly progressive cognitive decline, behavioral changes and magnetic resonance imagi...

    Authors: Yanjiao Du, Chao Liu, Congmin Ma, Xiaohui Xu, Xufeng Zhou, Haitao Zhou and Chao Huang

    Citation: BMC Neurology 2019 19:97

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  34. Content type: Study protocol

    Post-stroke lower limb spasticity (PSLLS) has a prevalence of 28–37%. PSLLS can cause difficulty in walking and reduce quality of life (QOL). Post stroke spasticity impairs the ability to intervene to improve ...

    Authors: Anupam Datta Gupta, Renuka Visvanathan, Ian Cameron, Simon A. Koblar, Stuart Howell and David Wilson

    Citation: BMC Neurology 2019 19:96

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  35. Content type: Case report

    Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a mitochondrial cytopathy caused by mutations in mitochondrial DNA. Clinical manifestation is typically before the age of 40.

    Authors: Tim Sinnecker, Michaela Andelova, Michael Mayr, Stephan Rüegg, Michael Sinnreich, Juergen Hench, Stephan Frank, André Schaller, Christoph Stippich, Jens Wuerfel and Leo H. Bonati

    Citation: BMC Neurology 2019 19:91

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  36. Content type: Research article

    In clinical practice, a large number of post-stroke survivors require nasogastric tube (NGT) placement and nasal feeding for a relatively long period. However, its impact on the swallowing function remains lar...

    Authors: Zhi-Yong Wang, Jian-Min Chen and Guo-Xin Ni

    Citation: BMC Neurology 2019 19:83

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  37. Content type: Research article

    Warfarin is evidence-based therapy for the prevention of cardioembolic stroke, but has not been studied for its effects on whole blood viscosity (WBV). This study investigated the effect of warfarin versus asp...

    Authors: Chan-Hyuk Lee, Keun-Hwa Jung, Daniel J. Cho and Seul-Ki Jeong

    Citation: BMC Neurology 2019 19:82

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  38. Content type: Research article

    Cerebellar hemorrhage is a potentially life-threatening condition and neurologic deterioration during hospitalization could lead to severe disability and poor outcome. Finds out the factors influencing neurolo...

    Authors: Yu-Ni Ho, Shih-Yuan Hsu, Yu-Tsai Lin, Fu-Chang Cheng, Yu-Jun Lin, Nai-Wen Tsai, Cheng-Hsien Lu and Hung-Chen Wang

    Citation: BMC Neurology 2019 19:81

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  39. Content type: Study protocol

    Complex brain arteriovenous malformations (bAVMs) in ≥3 Spetzler-Martin grades have long been challenges among cerebrovascular diseases. None of the traditional methods, such as microsurgical operation, endova...

    Authors: Mingze Wang, Yuming Jiao, Yong Cao, Shuo Wang and Jizong Zhao

    Citation: BMC Neurology 2019 19:75

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  40. Content type: Case report

    Spontaneous isolated posterior inferior cerebellar artery (PICA) dissection has been reported more frequently since high-resolution vessel wall magnetic resonance imaging (HR vw-MRI) was introduced to the fiel...

    Authors: Yong Soo Cho, Pahn Kyu Choi, Hyun Ju Seon, Dong Hun Kim, Byoung-Soo Shin and Hyun Goo Kang

    Citation: BMC Neurology 2019 19:74

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  41. Content type: Research article

    Intermittent theta burst stimulation (iTBS) is a form of repetitive transcranial stimulation that has been used to enhance upper limb (UL) motor recovery. However, only limited studies have examined its effica...

    Authors: Yu-Jen Chen, Ying-Zu Huang, Chung-Yao Chen, Chia-Ling Chen, Hsieh-Ching Chen, Ching-Yi Wu, Keh-Chung Lin and Tzu-ling Chang

    Citation: BMC Neurology 2019 19:69

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