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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Infection is the most important complication after acute stroke. This is substantially based on a stroke-induced immunosuppression. Heart rate variability (HRV) represents the autonomic nervous system activity...

    Authors: Dirk Brämer, Heike Hoyer, Albrecht Günther, Samuel Nowack, Frank M Brunkhorst, Otto W Witte and Dirk Hoyer

    Citation: BMC Neurology 2014 14:9

    Content type: Study protocol

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  2. Abnormalities in nocturnal blood pressure dipping are well known for its relationship to cardiovascular diseases. Cerebral microbleeds are frequently observed in patients with hypertension and are known to be ...

    Authors: Hyung-Min Kwon, Jae-Sung Lim, Young Seo Kim, Jangsup Moon, Hyeri Park, Hyun Young Kim, Young-Hyo Lim and Hyunwoo Nam

    Citation: BMC Neurology 2014 14:8

    Content type: Research article

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  3. Cerebral infarction caused by different reasons seems differ in fibrinogen levels, so the current work intends to explore the relationship between the fibrinogen level and subtypes of the TOAST criteria in the...

    Authors: Qi Lang, Muke Zhou, Hong Feng, Jian Guo, Ning Chen and Li He

    Citation: BMC Neurology 2013 13:207

    Content type: Research article

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  4. The detection of early neuropsychological abnormalities as precursors of cognitive decline of vascular origin in patients with lacunar stroke is a subject of increasing interest. The objective of this study wa...

    Authors: Lorena Blanco-Rojas, Adrià Arboix, David Canovas, Marta Grau-Olivares, Joan Carles Oliva Morera and Olga Parra

    Citation: BMC Neurology 2013 13:203

    Content type: Research article

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  5. Stroke campaigns are educating about the need to immediately contact the emergency medical system if symptoms occur. Despite higher stroke rates among patients with diabetics and some migrant populations, ther...

    Authors: Birgitta M Weltermann, Youcef Driouach-Bleckmann, Sabrina Reinders, Peter Berndt and Stefan Gesenhues

    Citation: BMC Neurology 2013 13:202

    Content type: Research article

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  6. In up to 30% of patients with ischemic stroke no definite etiology can be established. A significant proportion of cryptogenic stroke cases may be due to non-stenosing atherosclerotic plaques or low grade carotid...

    Authors: Anna Bayer-Karpinska, Florian Schwarz, Frank A Wollenweber, Holger Poppert, Tobias Boeckh-Behrens, Alexander Becker, Dirk A Clevert, Konstantin Nikolaou, Christian Opherk, Martin Dichgans and Tobias Saam

    Citation: BMC Neurology 2013 13:201

    Content type: Study protocol

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  7. Evidence indicates that the continuation of therapy among community-dwelling stroke survivors improves physical function. Community rehabilitation programmes often face limitations in terms of resources. It is...

    Authors: Devinder Kaur Ajit Singh, Nor Azlin Mohd Nordin, Noor Azah Abd Aziz, Beng Kooi Lim and Li Ching Soh

    Citation: BMC Neurology 2013 13:199

    Content type: Research article

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  8. Physical activity is believed to exert a beneficial effect on functional and cognitive rehabilitation of patients with stroke. Although studies have addressed the impact of physical exercise in cerebrovascular...

    Authors: Alexander H Nave, Jan M Kröber, Peter Brunecker, Jochen B Fiebach, Jonathan List, Ulrike Grittner, Matthias Endres, Andreas Meisel, Agnes Flöel and Martin Ebinger

    Citation: BMC Neurology 2013 13:197

    Content type: Study protocol

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  9. The Hajj Ceremony, the largest annual gathering in the world, is the most important life event for any Muslim. This study was designed to evaluate the incidence of stroke among Iranian pilgrims during the Hajj...

    Authors: Mahmoud Reza Azarpazhooh, Reza Bavarsad Shahripour, Moira K Kapral, Naghmeh Mokhber, Ali Shoeibi, Mohammad Taghi Farzadfard, Mohammad Reza Rafati, Amanda G Thrift, Negar Morovatdar, Seyed Aidin Sajedi and Amir Azarpazhooh

    Citation: BMC Neurology 2013 13:193

    Content type: Research article

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  10. Acid–base imbalance in various metabolic disturbances leads to human brain dysfunction. Compared with acidosis, the patients suffered from alkalosis demonstrate more severe neurological signs that are difficul...

    Authors: Shuyan Zhang, Piyun Sun, Zhongren Sun, Jingyu Zhang, Jinlong Zhou and Yingli Gu

    Citation: BMC Neurology 2013 13:192

    Content type: Research article

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  11. A wealth of published studies have been published on association between Chlamydia pneumoniae (C.pneumoniae) infection and cerebrovascular (CV) disease, but the results were inconsistent. This meta-analysis pr...

    Authors: Juan Chen, Meijia Zhu, Gaoting Ma, Zhangning Zhao and Zhongwen Sun

    Citation: BMC Neurology 2013 13:183

    Content type: Research article

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  12. Recently, plasma miRNAs have been reported as biomarkers for various diseases. However, the knowledge on the association of plasma miRNAs with ischemic stroke is still lacking. In this study, we investigated w...

    Authors: Guangwen Long, Feng Wang, Huaping Li, Zhongwei Yin, Chaugai Sandip, Yan Lou, Yan Wang, Chen Chen and Dao Wen Wang

    Citation: BMC Neurology 2013 13:178

    Content type: Research article

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  13. Subarachnoid hemorrhage (SAH) is a devastating cause of stroke, occurring in relatively young people. It has been suggested that some immune-mediated diseases may be associated with an increased risk of SAH.

    Authors: Sreeram V Ramagopalan, Julia Pakpoor, Olena Seminog, Raph Goldacre, Lee Graham and Michael J Goldacre

    Citation: BMC Neurology 2013 13:176

    Content type: Research article

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  14. Vertebral artery origin (VAO) stenosis is occasionally observed in patients who have acute ischemic stroke. We investigated the long-term outcomes and clinical significance of VAO stenosis in patients with acu...

    Authors: Young Jin Kim, Joon Hwa Lee, Jin Woo Choi, Hong Gee Roh, Young Il Chun, Ji-Sung Lee and Hahn Young Kim

    Citation: BMC Neurology 2013 13:171

    Content type: Research article

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  15. Cerebral vasculopathy have been described in Fabry disease, in which altered cerebral blood flow, vascular remodelling or impairment of endothelial function could be involved. Our study aims to evaluate these ...

    Authors: Tomás Segura, Oscar Ayo-Martín, Isabel Gómez-Fernandez, Carolina Andrés, Miguel A Barba and José Vivancos

    Citation: BMC Neurology 2013 13:170

    Content type: Research article

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  16. Prospective observation of hemodynamic changes before and after formation of brain aneurysms is often difficult. We used a vessel surface repair method to carry out a retrospective hemodynamic study before and...

    Authors: Wei-Jie Le, Yue-Qi Zhu, Ming-Hua Li, Lei Yan, Hua-Qiao Tan, Shi-Min Xiao and Ying-Sheng Cheng

    Citation: BMC Neurology 2013 13:166

    Content type: Research article

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  17. In-stent restenosis (ISR) is an important factor endangering the long-term safety and efficacy of carotid artery angioplasty and stenting (CAS). It is plausible that soft vulnerable plaques are more likely to ...

    Authors: Katrin Wasser, André Karch, Sonja Gröschel, Janin Witzenhausen, Klaus Gröschel, Mathias Bähr and Jan Liman

    Citation: BMC Neurology 2013 13:163

    Content type: Research article

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  18. Bone marrow-derived endothelial stem cells participate in vascular repairs. Numbers of circulating endothelial progenitor cells (cEPCs) are associated with atherosclerosis. Fibrinogen plays a key role in ather...

    Authors: Zhizhong Liu, Xiurong Ding, Fang Fang, Ruimin Wang, Yan Chen, Yuetao Ma, Guojun Zhang and Xixiong Kang

    Citation: BMC Neurology 2013 13:161

    Content type: Research article

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  19. The Stroke burden is increasing in many populations where health institutions may experience more patients. We wanted to examine whether incidence rates and absolute number of hospitalized stroke patients rema...

    Authors: Malene Nøhr Demant, Charlotte Andersson, Ole Ahlehoff, Mette Charlot, Jonas Bjerring Olesen, Anne Gjesing, Peter R Hansen, Gunnar H Gislason, Thomas Truelsen and Christian Torp-Pedersen

    Citation: BMC Neurology 2013 13:156

    Content type: Research article

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  20. Cardio embolism and cerebrovascular atherosclerosis are two major mechanisms of stroke. Studies investigating associations between advanced echocardiographic parameters and stroke mechanisms are limited.

    Authors: Quratulain Shaikh, Bilal Ahmed, Maryam Ahmed, Jamal Hussain Mahar, Masood Ahmad, Ayesha Ahmed, Farzin Majeed, Fariha Sadiq Ali, Maria Khan and Ayeesha Kamran Kamal

    Citation: BMC Neurology 2013 13:149

    Content type: Research article

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  21. Stroke is the second most common cause of death and disability worldwide. It is a multi-factorial disease influenced by both environmental and genetic factors. Studies from the different ethnic regions of worl...

    Authors: Amit Kumar, Ram Sagar, Pradeep Kumar, Jitendra K Sahu, Ashoo Grover, Achal K Srivastava, S Vivekanandhan and Kameshwar Prasad

    Citation: BMC Neurology 2013 13:136

    Content type: Study protocol

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  22. The clinical profiles of cerebellar cavernous malformations (CCMs) with and without associated developmental venous anomalies (DVAs) are not well known. The aims of this study were to analyze the clinical and ...

    Authors: Peifeng Zhang, Lingtong Liu, Yong Cao, Shuo Wang and Jizong Zhao

    Citation: BMC Neurology 2013 13:134

    Content type: Research article

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  23. Stroke is the 4th leading cause of death and 1st leading cause of disability in Singapore. However the information on long-term post stroke outcomes for Singaporean patients was limited. This study aimed to in...

    Authors: Yan Sun, Sze Haur Lee, Bee Hoon Heng and Vivien S Chin

    Citation: BMC Neurology 2013 13:133

    Content type: Research article

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  24. Silent brain infarcts are detected by neuroimaging in up to 20% of asymptomatic patients based on population studies. They are five times more frequent than stroke in general population, and increase significa...

    Authors: Iolanda Riba-Llena, Carmen Ioana Jarca, Xavier Mundet, Jose L Tovar, Francesc Orfila, Antonio López-Rueda, Cristina Nafría, Jose L Fernández, Xavier Castañé, Mar Domingo, José Álvarez-Sabín, Inés Fernández-Cortiñas, Olga Maisterra, Joan Montaner and Pilar Delgado

    Citation: BMC Neurology 2013 13:130

    Content type: Study protocol

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  25. Despite heart failure being a substantial risk factor for stroke, few studies have evaluated the predictive value of heart dysfunction for all-cause mortality in patients with acute ischemic stroke, in particu...

    Authors: Alexandra Holmström, Michael LX Fu, Clara Hjalmarsson, Lena Bokemark and Björn Andersson

    Citation: BMC Neurology 2013 13:122

    Content type: Research article

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  26. Diabetes constitutes a risk factor for stroke that also aggravates stroke prognosis. Several prognostic models have been developed for the evaluation of neurologic status, severity, short-term functional outco...

    Authors: Vasileios Dragoumanos, Konstantinos N Tzirogiannis, Georgios I Panoutsopoulos, Konstantinos Krikonis, Evangelos Fousteris, Maria Vourvou, Georgios Elesnitsalis, Nikolaos Melas, Kalliopi T Kourentzi and Andreas Melidonis

    Citation: BMC Neurology 2013 13:121

    Content type: Research article

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  27. Stroke is the fourth leading cause of death in the U.S. and stroke mortality rates differ substantially by ethnic group. The impact of adherence to the USDA dietary guidelines on risk for fatal stroke among di...

    Authors: Sangita Sharma, Mohammadreza Pakserescht, Kennedy Cruickshank, Deborah M Green and Laurence N Kolonel

    Citation: BMC Neurology 2013 13:120

    Content type: Research article

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  28. Subarachnoid hemorrhage is a common and dangerous disease with an unfavorable prognosis. Patients with poor-grade subarachnoid hemorrhage (Hunt & Hess Grades 4–5) are unconscious on admission. Because of the h...

    Authors: Qiao Zhang, Lu Ma, Yi Liu, Min He, Hong Sun, Xiang Wang, Yuan Fang, Xu-hui Hui and Chao You

    Citation: BMC Neurology 2013 13:108

    Content type: Study protocol

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  29. Neuroprotective strategies in ischemic stroke are an important challenge in clinical and experimental research as an adjunct to reperfusion therapy that may reduce neurologic injury and improve outcome. The ne...

    Authors: Marc Hein, Norbert Zoremba, Chistian Bleilevens, Christian Bruells, Rolf Rossaint and Anna B Roehl

    Citation: BMC Neurology 2013 13:106

    Content type: Research article

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  30. The etiology of transient monocular blindness (TMB) in patients without carotid stenosis has been linked to ocular venous hypertension, for their increased retrobulbar vascular resistance, sustained retinal ve...

    Authors: Chun-Yu Cheng, Feng-Chi Chang, A-Ching Chao, Chih-Ping Chung and Han-Hwa Hu

    Citation: BMC Neurology 2013 13:94

    Content type: Research article

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  31. Regaining independent ambulation is the top priority for individuals recovering from stroke. Thus, physical rehabilitation post-stroke should focus on improving walking function and endurance. However, the amo...

    Authors: Avril Mansfield, Jennifer S Wong, Mark Bayley, Lou Biasin, Dina Brooks, Karen Brunton, Jo-Anne Howe, Elizabeth L Inness, Simon Jones, Jackie Lymburner, Ramona Mileris and William E McIlroy

    Citation: BMC Neurology 2013 13:93

    Content type: Study protocol

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  32. Ischemic stroke in young adults is a major health problem being associated with a higher vascular morbidity and mortality compared to controls, and a stroke recurrence rate of 25% during the first decade. The ...

    Authors: Annette Fromm, Lars Thomassen, Halvor Naess, Rudy Meijer, Geir Egil Eide, Jostein Kråkenes, Christian A Vedeler, Eva Gerdts, Terje H Larsen, Karel K-J Kuiper, Elin Laxdal, David Russell, Turgut Tatlisumak and Ulrike Waje-Andreassen

    Citation: BMC Neurology 2013 13:89

    Content type: Study protocol

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  33. Speech disturbance is a common symptom of stroke and is important as a prompt identifier of the event. The frequency of the symptom among each stroke subtype, differences between patients with and without spee...

    Authors: Kazuo Shigematsu, Hiromi Nakano, Yoshiyuki Watanabe, Tatsuyuki Sekimoto, Kouichiro Shimizu, Akihiko Nishizawa, Atsushi Okumura and Masahiro Makino

    Citation: BMC Neurology 2013 13:87

    Content type: Research article

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  34. The quantification of the flow returning from the head through the cervical veins and the collaterals of the internal jugular vein (IJV), is becoming of prominent interest in clinical practice. We developed a ...

    Authors: Paolo Zamboni, Francesco Sisini, Erica Menegatti, Angelo Taibi, Anna Maria Malagoni, Sandra Morovic and Mauro Gambaccini

    Citation: BMC Neurology 2013 13:81

    Content type: Research article

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  35. Stroke has emerged as a significant and escalating health problem for Asian populations. We compared risk factors, quality of care and risk of death or recurrent stroke in South Asian, East Asian and White pat...

    Authors: Nadia A Khan, Hude Quan, Michael D Hill, Louise Pilote, Finlay A McAlister, Anita Palepu, Baiju R Shah, Limei Zhou, Hong Zhen and Moira K Kapral

    Citation: BMC Neurology 2013 13:74

    Content type: Research article

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  36. Recovery of upper limb function after stroke is poor. The acute to subacutephase after stroke is the optimal time window to promote the recovery ofupper limb function. The dose and content of training provided...

    Authors: Sandra G Brauer, Kathryn S Hayward, Richard G Carson, Andrew G Cresswell and Ruth N Barker

    Citation: BMC Neurology 2013 13:71

    Content type: Study protocol

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  37. Coping style is one of the determinants of health-related quality of life after stroke. Stroke patients make less use of active problem-oriented coping styles than other brain damaged patients. Coping styles c...

    Authors: Marieke M Visser, Majanka H Heijenbrok-Kal, Adriaan van ’t Spijker, Gerard M Ribbers and Jan JV Busschbach

    Citation: BMC Neurology 2013 13:67

    Content type: Study protocol

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  38. Stroke is the disease with the highest costs for hospital care and also after discharge. Early supported discharge (ESD) has shown to be efficient and safe and the best results with well-organised discharge te...

    Authors: Katharina S Sunnerhagen, Anna Danielsson, Lena Rafsten, Ann Björkdahl, Åsa B Axelsson, Åsa Nordin, Cathrine A Petersson, Åsa Lundgren-Nilsson and Karin Fröjd

    Citation: BMC Neurology 2013 13:66

    Content type: Study protocol

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  39. Clinical-Diffusion mismatch (CDM; NIHSS score ≥8 & DWI lesion volume ≤25 mL) and Perfusion-Diffusion mismatch (PDM; difference >20% between initial DWI and MTT lesion volumes) have been proposed as surrogates ...

    Authors: Manuel Rodríguez-Yáñez, Mar Castellanos, Tomás Sobrino, David Brea, Pedro Ramos-Cabrer, Salvador Pedraza, José A Castiñeiras, Joaquín Serena, Antonio Dávalos, José Castillo and Miguel Blanco

    Citation: BMC Neurology 2013 13:62

    Content type: Research article

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  40. Limited information has been published regarding standard quality assurance (QA) procedures for stroke registries. We share our experience regarding the establishment of enhanced QA procedures for the Universi...

    Authors: Mohammad H Rahbar, Nicole R Gonzales, Manouchehr Ardjomand-Hessabi, Amirali Tahanan, Melvin R Sline, Hui Peng, Renganayaki Pandurengan, Farhaan S Vahidy, Jessica D Tanksley, Ayodeji A Delano, Rene M Malazarte, Ellie E Choi, Sean I Savitz and James C Grotta

    Citation: BMC Neurology 2013 13:61

    Content type: Research article

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  41. Few studies have examined both ischemic and hemorrhagic stroke to identify prognostic factors associated to long-term stroke survival. We investigated long-term survival and predictors that could adversely inf...

    Authors: Alessandra C Goulart, Tiotrefis G Fernandes, Itamar S Santos, Airlane P Alencar, Isabela M Bensenor and Paulo A Lotufo

    Citation: BMC Neurology 2013 13:51

    Content type: Research article

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  42. This study attempts to explore the clinical features, possible mechanisms and prognosis of the neurologic complications in patients with acute aortic dissection (AD).

    Authors: Seung-Jae Lee, Jae-Hyun Kim, Chan-Young Na, Sam-Sae Oh, Yang-Min Kim, Chang-Keun Lee and Dal-Soo Lim

    Citation: BMC Neurology 2013 13:46

    Content type: Research article

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