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Cerebrovascular disease and stroke

Section edited by Erwin Stolz and Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Content type: Research article

    The efficacy of early supported discharge (ESD) has not been tested in current stroke care setting, which provide relatively short hospital stays, access to hyper-acute therapies and early carotid stenosis int...

    Authors: Anna Bråndal, Marie Eriksson, Eva-Lotta Glader and Per Wester

    Citation: BMC Neurology 2019 19:40

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  2. Content type: Study protocol

    After discharge from hospital following a stroke, prescriptions of community-based rehabilitation are often downgraded to “maintenance” rehabilitation or discontinued. This classic therapeutic behavior stems f...

    Authors: Jean-Michel Gracies, Maud Pradines, Mouna Ghédira, Catherine-Marie Loche, Valentina Mardale, Catherine Hennegrave, Caroline Gault-Colas, Etienne Audureau, Emilie Hutin, Marjolaine Baude and Nicolas Bayle

    Citation: BMC Neurology 2019 19:39

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  3. Content type: Case report

    Moyamoya vasculopathy (MMV) associated with Graves’ disease (GD) is a rare condition resulting in ischemic stroke accompanied by thyrotoxicity. Radiological findings of vasculitis have been reported in the wal...

    Authors: Hiroto Ito, Syunsuke Yokoi, Kinya Yokoyama, Takumi Asai, Kenji Uda, Yoshio Araki, Syuntaro Takasu, Rei Kobayashi, Hisashi Okada and Satoshi Okuda

    Citation: BMC Neurology 2019 19:34

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  4. Content type: Research article

    Ischemic stroke is a leading cause of mortality and morbidity worldwide. Stenosis or blockage of an artery from atherosclerosis can cause insufficient cerebral blood supply, which leads to ischemic stroke. It ...

    Authors: Yan Jiang, Xiaomin Liu, Yifeng Du and Shengnian Zhou

    Citation: BMC Neurology 2019 19:31

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  5. Content type: Case report

    Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presente...

    Authors: Dian He, YunLi Yu, Shan Wu, ShuFen Tian, Hui Yu, Shu Xu and Lan Chu

    Citation: BMC Neurology 2019 19:26

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  6. Content type: Research article

    Atrial fibrillation (AF) is present in 15–20% of patients with acute ischemic stroke. Oral anticoagulation reduces the risk of AF-related recurrent stroke but clinical guideline recommendations are rather vagu...

    Authors: Alexander Wutzler, Christos Krogias, Anna Grau, Roland Veltkamp, Peter U. Heuschmann and Karl Georg Haeusler

    Citation: BMC Neurology 2019 19:25

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  7. Content type: Study protocol

    Malnutrition is one of the crucial factors associated with poor prognosis in critical ill patients, yet a significant evidence gap surrounds the management of initial enteral feeding in severe stroke. The Opti...

    Authors: Fang Yuan, Fang Yang, Wei Zhang, Yi Jia, Yaling Ma, Yongcai Qu, Xinglai Wang, Kang Huo, Chengkai Wang, Xiangjun Yuan, Chaohui Song, Bei Zhang and Wen Jiang

    Citation: BMC Neurology 2019 19:24

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  8. Content type: Research article

    Endothelial progenitor cells (EPCs) play an important role in ischemic stroke. However, there are few studies on the relationship between EPC and nondisabling ischemic cerebrovascular events. Our aim was to in...

    Authors: Wang Zhao, Libo Zhao, Juan Liao, Yong Luo and Lanying He

    Citation: BMC Neurology 2019 19:22

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  9. Content type: Research article

    The burden of hospital readmission after stroke is substantial, but little knowledge exists on factors associated with long-term readmission after stroke. In a cohort comprising patients with ischemic stroke a...

    Authors: Anna Therese Bjerkreim, Halvor Naess, Andrej Netland Khanevski, Lars Thomassen, Ulrike Waje-Andreassen and Nicola Logallo

    Citation: BMC Neurology 2019 19:15

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  10. Content type: Case report

    The signs and symptoms of acute alcohol intoxication resemble those of vertebrobasilar stroke. Due to their shared symptoms including double vision, nystagmus, dysarthria, and ataxia, the differential diagnosi...

    Authors: Tamas Arokszallasi, Eszter Balogh, Laszlo Csiba, Istvan Fekete, Klara Fekete and Laszlo Olah

    Citation: BMC Neurology 2019 19:14

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  11. Content type: Research article

    Futile reperfusion (poor functional status despite successful reperfusion) was observed in up to 67% of patients enrolled in recent endovascular treatment (EVT) clinical trials. We investigated the impact of b...

    Authors: Sang-Hwa Lee, Beom Joon Kim, Moon-Ku Han, Tai Hwan Park, Kyung Bok Lee, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Jae Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Jun Lee, Soo Joo Lee, Jae Guk Kim, Jong-Moo Park, Kyusik Kang…

    Citation: BMC Neurology 2019 19:11

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  12. Content type: Research article

    Single acute infarction (SAI) usually had lower risk of stroke recurrence than multiple acute infarctions (MAIs) in minor stroke. To evaluate whether all SAI had lower risk of stroke recurrence than MAIs in mi...

    Authors: Guangyao Wang, Jing Jing, Yuesong Pan, Xia Meng, Xingquan Zhao, Liping Liu, Hao Li, David Wang, Yongjun Wang and Yilong Wang

    Citation: BMC Neurology 2019 19:7

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  13. Content type: Research article

    Transient ischemic attack (TIA) is a risk factor of stroke. Modern treatment regimens and changing risk factors in the population justify new estimates of stroke risk after TIA, and evaluation of the recommend...

    Authors: Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Janne Kutschera Sund, Hild Fjærtoft, Stephan Schüler, Jens Wilhelm Horn, Geir Bråthen, Ann-Grete Midtsæther, Åse Hagen Morsund, Marja-Liisa Lillebø, Yngve Müller Seljeseth and Bent Indredavik

    Citation: BMC Neurology 2019 19:2

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  14. Content type: Research article

    Unplanned readmission within 31 days of discharge after stroke is a useful indicator for monitoring quality of hospital care. We evaluated the risk factors associated with 31-day unplanned readmission of strok...

    Authors: Tiancai Wen, Baoyan Liu, Xia Wan, Xiaoping Zhang, Jin Zhang, Xuezhong Zhou, Alexander Y. L. Lau and Yanning Zhang

    Citation: BMC Neurology 2018 18:218

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  15. Content type: Research article

    In acute ischemic stroke patients, telestroke technology provides sustainable approaches to improve the use of thrombolysis therapy. How this is achieved as it relates to inclusion or exclusion of clinical ris...

    Authors: Leanne Brecthel, Jordan Gainey, Alexandria Penwell and Thomas I. Nathaniel

    Citation: BMC Neurology 2018 18:215

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  16. Content type: Case report

    Cortical ischemic lesions represent the predominant pathomorphological pattern of focal lesions after aneurysmal subarachnoid hemorrhage (aSAH). Autopsy studies suggest that they occur adjacent to subarachnoid...

    Authors: Christian Schinke, Viktor Horst, Ludwig Schlemm, Matthias Wawra, Michael Scheel, Jed A. Hartings and Jens P. Dreier

    Citation: BMC Neurology 2018 18:210

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  17. Content type: Research article

    Two-dimensional high-resolution MRI (2D HRMRI) faces many technical challenges for fully assessing morphologic characteristics of inherent tortuous basilar arteries. Our aim was to investigate remodeling mecha...

    Authors: Runcai Guo, Xuebin Zhang, Xianjin Zhu, Zunjing Liu and Sheng Xie

    Citation: BMC Neurology 2018 18:206

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  18. Content type: Research article

    Cerebrospinal fluid (CSF) biomarkers reflect ongoing processes in the brain. Growth-associated protein 43 (GAP-43) is highly upregulated in brain tissue shortly after experimental ischemia suggesting the CSF G...

    Authors: Åsa Sandelius, Nicholas C. Cullen, Åsa Källén, Lars Rosengren, Crister Jensen, Vesna Kostanjevecki, Manu Vandijck, Henrik Zetterberg and Kaj Blennow

    Citation: BMC Neurology 2018 18:202

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  19. Content type: Research article

    Elevated plasma homocysteine (Hcy) is an independent risk factor for ischemic stroke. This study aimed to evaluate the association between Hcy levels and intracranial plaque characteristics and to investigate ...

    Authors: Shan shan Lu, Jun Xie, Chun qiu Su, Song Ge, Hai bin Shi and Xun ning Hong

    Citation: BMC Neurology 2018 18:200

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  20. Content type: Case report

    The majority of ruptured intracranial aneurysms are combined with subarachnoid hemorrhage, but patients with only intracerebral hematoma without any subarachnoid hemorrhage are extremely rare.

    Authors: Guangyong Chen, Meiling Xu, Long Ma, Yufei Gao, Chengyan He and Jinnan Zhang

    Citation: BMC Neurology 2018 18:197

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  21. Content type: Research article

    Warfarin therapies not only are used to prevent stroke in patients with high risk of cardioembolism such as patients with atrial fibrillation (AF) and rheumatic heart disease (RHD), but also was associated wit...

    Authors: Jiaying Zhu, Mengmeng Ma, Yijia Guo, Muke Zhou, Jian Guo and Li He

    Citation: BMC Neurology 2018 18:194

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  22. Content type: Study protocol

    Early and late onset post-stroke cognitive impairment (PCI) contributes substantially to disability following stroke, and is a high priority within stroke research. The aetiology for PCI is complex and related...

    Authors: Pernille Thingstad, Torunn Askim, Mona K. Beyer, Geir Bråthen, Hanne Ellekjær, Hege Ihle-Hansen, Anne Brita Knapskog, Stian Lydersen, Ragnhild Munthe-Kaas, Halvor Næss, Sarah T. Pendlebury, Yngve Muller Seljeseth and Ingvild Saltvedt

    Citation: BMC Neurology 2018 18:193

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  23. Content type: Research article

    There is limited data on the effects of medication-related adverse events occurring during inpatient stays for stroke. The objectives of our study were to characterize reasons for acute readmission after acute...

    Authors: James A. G. Crispo, Dylan P. Thibault, Yannick Fortin, Daniel Krewski and Allison W. Willis

    Citation: BMC Neurology 2018 18:192

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  24. Content type: Study protocol

    Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of future cardiovascular events. Despite compelling evidence about the efficacy of secondary prevention, a substantial gap ex...

    Authors: Thomas Toell, Christian Boehme, Lukas Mayer, Stefan Krebs, Clemens Lang, Karin Willeit, Barbara Prantl, Michael Knoflach, Gerhard Rumpold, Gudrun Schoenherr, Andrea Griesmacher, Peter Willeit, Julia Ferrari, Wilfried Lang, Stefan Kiechl and Johann Willeit

    Citation: BMC Neurology 2018 18:187

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  25. Content type: Research article

    Physical activity (PA) is associated with lower risk of stroke. We tested the hypothesis that lack of pre-stroke PA is an independent predictor of poor outcome after first-ever ischemic stroke.

    Authors: Christian Urbanek, Viola Gokel, Anton Safer, Heiko Becher, Armin J. Grau, Florian Buggle and Frederick Palm

    Citation: BMC Neurology 2018 18:181

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  26. Content type: Research article

    About 30% of stroke patients suffer from aphasia. As aphasia strongly affects daily life, most patients request a prediction of outcome of their language function. Prognostic models provide predictions of outc...

    Authors: Femke Nouwens, Evy G. Visch-Brink, Hanane El Hachioui, Hester F. Lingsma, Mieke W. M. E. van de Sandt-Koenderman, Diederik W. J. Dippel, Peter J. Koudstaal and Lonneke M. L. de Lau

    Citation: BMC Neurology 2018 18:170

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  27. Content type: Research article

    Recent studies have shown conflicting results regarding the effect of hydrogel coils for treating intracranial aneurysm compared to bare platinum coils. We implemented a meta-analysis to assess the value of hy...

    Authors: Tao Xue, Zhouqing Chen, Weiwei Lin, Jiayi Xu, Xuming Shen and Zhong Wang

    Citation: BMC Neurology 2018 18:167

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  28. Content type: Research article

    Studying the impact of demographic changes and progress in the management of stroke patients is necessary in order to organize care structures for the coming years. Consequently, we analyzed the prognostic tre...

    Authors: Emilio Rodríguez-Castro, Iria López-Dequit, María Santamaría-Cadavid, Susana Arias-Rivas, Manuel Rodríguez-Yáñez, José Manuel Pumar, Pablo Hervella, Esteban López-Arias, Andrés da Silva-Candal, Ana Estany, María Piñeiro-Lamas, Tomás Sobrino, Francisco Campos, Manuel Portela, Manuel Vázquez-Lima, José Castillo…

    Citation: BMC Neurology 2018 18:164

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  29. Content type: Case report

    Cerebral venous sinus thrombosis or stenosis (here collectively referred to as cerebral venous sinus occlusion, CVSO) can cause chronically-elevated intracranial pressure (ICP). Patients may have no neurologic...

    Authors: Tongtao Zhao, Gang Wang, Jiaman Dai, Yong Liu, Yi Wang and Shiying Li

    Citation: BMC Neurology 2018 18:159

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  30. Content type: Case report

    The computed tomography (CT) finding of a pseudo-subarachnoid hemorrhage (SAH) may lead the treating physician into a diagnostic dilemma. We present a case of a pseudo-SAH in a patient with post-resuscitative ...

    Authors: Mohamad Syafeeq Faeez Md Noh and Anna Misyail Abdul Rashid

    Citation: BMC Neurology 2018 18:157

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  31. Content type: Research article

    Though genetic and environmental determinants of systemic haemodynamic have been reported, surprisingly little is known about their influences on cerebral haemodynamics. We assessed the potential geographical ...

    Authors: Angela S. M. Salinet, Ronney B. Panerai, Juliana Caldas, Ricardo C. Nogueira, Adriana B. Conforto, Manoel J. Texeira, Edson Bor-Seng-Shu and Thompson G. Robinson

    Citation: BMC Neurology 2018 18:156

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  32. Content type: Research article

    Strategies are needed to improve adherence to the blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) level recommendations after stroke and transient ischemic attack (TIA). We investigated whe...

    Authors: Joachim Ögren, Anna-Lotta Irewall, Lars Söderström and Thomas Mooe

    Citation: BMC Neurology 2018 18:153

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  33. Content type: Research article

    Patients with ischemic cerebrovascular diseases are more likely to suffer from intracranial aneurysms, and their surgical treatment has a growing controversy in this condition. The current case series was aime...

    Authors: Yangrui Zheng and Chen Wu

    Citation: BMC Neurology 2018 18:142

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  34. Content type: Research article

    Various outcome measures are used for the assessment of balance and mobility in patients with stroke. The purpose of the present study was to examine test-retest reliability, construct validity, and responsive...

    Authors: Ahmad H. Alghadir, Einas S. Al-Eisa, Shahnawaz Anwer and Bibhuti Sarkar

    Citation: BMC Neurology 2018 18:141

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  35. Content type: Case report

    Rheumatoid meningitis presenting with a stroke-like attack (RMSA) is a rare manifestation of rheumatoid arthritis (RA). When the patients arrive within the time-window for recombinant tissue plasminogen activa...

    Authors: Masashi Akamatsu, Futaba Maki, Hisanao Akiyama, Daisuke Hara, Masashi Hoshino and Yasuhiro Hasegawa

    Citation: BMC Neurology 2018 18:139

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  36. Content type: Research article

    Early mobilization has been an important part of acute stroke unit treatment. However, early and intense mobilization within the first 24 h post stroke may cause an unfavorable outcome. Recently, objective mea...

    Authors: Ole Petter Norvang, Anne Hokstad, Kristin Taraldsen, Xiangchun Tan, Stian Lydersen, Bent Indredavik and Torunn Askim

    Citation: BMC Neurology 2018 18:138

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    The Correction to this article has been published in BMC Neurology 2019 19:8

  37. Content type: Research article

    Recently, minimal invasive surgery (MIS) has been applied as a common therapeutic approach for treatment of hypertensive intracerebral hemorrhage (HICH). However, the efficacy and safety of MIS is still contro...

    Authors: Yiping Tang, Fengqiong Yin, Dengli Fu, Xinhai Gao, Zhengchao Lv and Xuetao Li

    Citation: BMC Neurology 2018 18:136

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  38. Content type: Research article

    The SPAN-100 index adds patient age and baseline NIHSS-score and was introduced to predict clinical outcome after acute ischemic stroke (AIS). Even with high NIHSS-scores younger patients cannot reach a SPAN-1...

    Authors: Cornelia Möbius, Christian Blinzler, Stefan Schwab, Martin Köhrmann and Lorenz Breuer

    Citation: BMC Neurology 2018 18:129

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  39. Content type: Research article

    Our aim was to compare the perioperative time courses of matrix metalloproteinase-9 (MMP-9) and its inhibitor (TIMP-1) in during carotid endarterectomy (CEA) and carotid artery stenting (CAS).

    Authors: Ákos Mérei, Bálint Nagy, Gábor Woth, János Lantos, Ferenc Kövér, Lajos Bogár and Diána Mühl

    Citation: BMC Neurology 2018 18:128

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  40. Content type: Case report

    Benign gynecologic tumor, such as uterine adenomyosis, has been suggested to develop hypercoagulability. Although some cases of cerebral infarction associated with adenomyosis have been reported, the mechanism...

    Authors: Yasuhiro Aso, Ryo Chikazawa, Yuki Kimura, Noriyuki Kimura and Etsuro Matsubara

    Citation: BMC Neurology 2018 18:119

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  41. Content type: Research article

    Insulin-like growth factor I (IGF-I) has neuroprotective effects in experimental ischemic stroke (IS). However, in patients who have suffered IS, various associations between the levels of serum IGF-I (s-IGF-I...

    Authors: N. David Åberg, Daniel Åberg, Katarina Jood, Michael Nilsson, Christian Blomstrand, H. Georg Kuhn, Johan Svensson, Christina Jern and Jörgen Isgaard

    Citation: BMC Neurology 2018 18:106

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  42. Content type: Study protocol

    After stroke, spasticity of the rectus femoris (RF) and triceps surae (TS) muscles frequently alters the gait pattern. Knee flexion and ankle dorsiflexion in swing are often reduced, respectively called Stiff ...

    Authors: Anthony Supiot, Maxime Geiger, Djamel Bensmail, Phillippe Aegerter, Didier Pradon and Nicolas Roche

    Citation: BMC Neurology 2018 18:104

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  43. Content type: Research article

    Brief measures of health-related quality of life (HRQOL) that assess both patient-reported functioning and well-being after stroke are scarce. The objective of this study was to examine reliability and validit...

    Authors: Guri Heiberg, Synne Garder Pedersen, Oddgeir Friborg, Jørgen Feldbæk Nielsen, Henriette Stabel Holm, Nicole Steinbüchel von, Cathrine Arntzen and Audny Anke

    Citation: BMC Neurology 2018 18:98

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  44. Content type: Research article

    Young ischemic stroke patients are common while classification and analysis based upon imaging characteristics are rarely reported. We intend to compare the clinical and MRI characteristics of cerebral stroke ...

    Authors: Zhang-Ning Zhao, Xiao-Lin Li, Jin-Zhi Liu, Zhi-Ming Jiang and Ai-Hua Wang

    Citation: BMC Neurology 2018 18:87

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