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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. To study the association of caregiver factors and stroke patient factors with rehospitalizations over the first 3 months and subsequent 3–12 months post-stroke in Singapore.

    Authors: Shilpa Tyagi, Gerald C. H. Koh, Nan Luo, Kelvin B. Tan, Helen Hoenig, David B. Matchar, Joanne Yoong, Angelique Chan, Kim En Lee, N. Venketasubramanian, Edward Menon, Kin Ming Chan, Deidre Anne De Silva, Philip Yap, Boon Yeow Tan, Effie Chew…

    Citation: BMC Neurology 2019 19:267

    Content type: Research article

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  2. Failing to recognise the signs and symptoms of subarachnoid haemorrhage (SAH) causes diagnostic delay and may result in poorer outcomes. We report a rare case of SAH secondary to a vertebral artery dissection ...

    Authors: Lloyd Steele, Muhammad Hasan Raza, Richard Perry, Neil Rane and Sophie J. Camp

    Citation: BMC Neurology 2019 19:262

    Content type: Case report

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  3. The aim of this study was to evaluate the correlation between significant asymptomatic carotid artery stenosis (ACAS) and severity of peripheral arterial occlusive disease (PAOD) in the lower limb, and to inve...

    Authors: Zhongjie Pan, Ruitao Wang, Li Li and Hua Zhang

    Citation: BMC Neurology 2019 19:259

    Content type: Research article

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  4. Elevated blood pressure (BP) at emergency department (ED) presentation and advancing age have been associated with risk of ischemic stroke; however, the relationship between BP, age, and transient ischemic att...

    Authors: Andrew M. Penn, Nicole S. Croteau, Kristine Votova, Colin Sedgwick, Robert F. Balshaw, Shelagh B. Coutts, Melanie Penn, Kaitlin Blackwood, Maximilian B. Bibok, Viera Saly, Janka Hegedus, Amy Y. X. Yu, Charlotte Zerna, Evgenia Klourfeld and Mary L. Lesperance

    Citation: BMC Neurology 2019 19:251

    Content type: Research article

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  5. The purpose of this study was to report our preliminary experience of stent-assisted coiling (SAC) of wide-necked intracranial aneurysms with a single microcatheter in patients with parent arteries that were s...

    Authors: Keun Young Park, Chang Ki Jang, Jae Whan Lee, Dong Joon Kim, Byung Moon Kim and Joonho Chung

    Citation: BMC Neurology 2019 19:245

    Content type: Technical advance

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  6. Atrial fibrillation (AF) is a common cause of cerebral infarction, which could lead to endothelial dysfunction, increased reactive oxygen species (ROS) and oxidized low density lipoprotein (Ox-LDL).AF is assoc...

    Authors: Lanying He, Ronghua Xu, Jian Wang, Lili Zhang, Lijuan Zhang, Wang Zhao and Weiwei Dong

    Citation: BMC Neurology 2019 19:240

    Content type: Research article

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  7. Previously there have been found higher circulating malondialdehyde levels during the first week of ischemic stroke in patients with worst neurological functional outcome, and at moment of ischemic stroke in n...

    Authors: Leonardo Lorente, María M. Martín, Pedro Abreu-González, Rafael Sabatel, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez and Victor García-Marín

    Citation: BMC Neurology 2019 19:238

    Content type: Research article

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  8. Brain ischemia activates the parasympathetic cholinergic pathway in animal models of human disease. However, it remains unknown whether activation of the cholinergic pathway impacts immune defenses and disease...

    Authors: Meng Yuan, Bin Han, Yiping Xia, Ye Liu, Chunyang Wang and Chao Zhang

    Citation: BMC Neurology 2019 19:236

    Content type: Research article

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  9. Radiation therapy can cause cerebral arteriopahty, resulting in ischemic stroke. We document late-delayed cerebral arteriopathy by high-resolution magnetic resonance imaging (HR-MRI) in a middle aged man who h...

    Authors: Huan Chen, Xiuhua Li, Xiaoyu Zhang, Wenjuan Xu, Fei Mao, Mengxin Bao and Meijia Zhu

    Citation: BMC Neurology 2019 19:232

    Content type: Case report

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  10. Endovascular treatment (EVT) is advocated for acute ischaemic stroke with large-vessel occlusion (LVO), but perioperative periods are challenging. This study investigated the relationship between post-EVT shor...

    Authors: Tianli Zhang, Xiaolong Wang, Chao Wen, Feng Zhou, Shengwei Gao, Xiaodong Zhang, Shiqin Lin, Jing Shi and Weirong Li

    Citation: BMC Neurology 2019 19:228

    Content type: Research article

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  11. Due to improvements in both the quality and availability of intracranial imaging as well as the evolution of surgical and endovascular techniques during the last decade, the number of treatments of unruptured ...

    Authors: Christin Campe, Jens Neumann, I. Erol Sandalcioglu, Ali Rashidi and Michael Luchtmann

    Citation: BMC Neurology 2019 19:226

    Content type: Case report

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  12. Self-rated health (SRH) allows for comparison and identification of the health status of various populations. The aim of this study was to conduct a systematic review of the literature to expand the understand...

    Authors: Érika de Freitas Araújo, Ramon Távora Viana, Luci Fuscaldi Teixeira-Salmela, Lidiane Andrea Oliveira Lima and Christina Danielli Coelho de Morais Faria

    Citation: BMC Neurology 2019 19:221

    Content type: Research article

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  13. Stroke patients are often affected by long-term disabilities with needs concerning social issues. There is relatively little consideration of social recovery of patients and the support required to return to w...

    Authors: Sophie Lehnerer, Benjamin Hotter, Inken Padberg, Petra Knispel, Dike Remstedt, Andrea Liebenau, Ulrike Grittner, Ian Wellwood and Andreas Meisel

    Citation: BMC Neurology 2019 19:220

    Content type: Research article

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  14. The global burden of stroke epidemiology is changing rapidly. Over the 1990–2013 periods, there was a significant increase in the absolute number of deaths and incident events of stroke. The burden of stroke v...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:213

    Content type: Research article

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  15. Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei pro...

    Authors: Yanfeng Zhou, Shijiao Yan, Xingyue Song, Yanhong Gong, Wenzhen Li, Mengdie Wang, Xiaoxv Yin, Bo Hu and Zuxun Lu

    Citation: BMC Neurology 2019 19:202

    Content type: Research article

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  16. Mechanical thrombectomy (MT) using stent retriever assisted vacuum-locked extraction (SAVE) is a promising method for anterior circulation strokes. We present our experience with SAVE for large vessel occlusio...

    Authors: Volker Maus, Hanna Styczen, Jan Liman, Ilko Maier, Alex Brehm, Ioannis Tsogkas and Marios-Nikos Psychogios

    Citation: BMC Neurology 2019 19:197

    Content type: Research article

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  17. Recovery of upper limb function in individuals after a stroke remains challenging. Modified constraint-induced movement therapy (m-CIMT) has strong evidence for increasing the use and recovery of sensorimotor ...

    Authors: Erika Shirley Moreira da Silva, Gabriela Lopes Santos, Aparecida Maria Catai, Alexandra Borstad, Natália Pereira Duarte Furtado, Isabela Arruda Verzola Aniceto and Thiago Luiz Russo

    Citation: BMC Neurology 2019 19:196

    Content type: Study protocol

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    The Correction to this article has been published in BMC Neurology 2019 19:225

  18. Emotional processes and responses are underestimated in stroke patients because the massive clinical picture of large hemispheric strokes often hides these symptoms. We report on a patient with peculiar unplea...

    Authors: Mariagiovanna Cantone, Giuseppe Lanza, Rita Bella, Giovanni Pennisi, Paola Santalucia, Placido Bramanti and Manuela Pennisi

    Citation: BMC Neurology 2019 19:193

    Content type: Case report

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  19. The topographic location of acute pontine infarction is associated with clinical syndromes and prognosis. Previous studies focused on isolated pontine infarction, but the topographic location of unisolated pon...

    Authors: Jiehong Huang, Zhihua Qiu, Piansi Zhou, Jianming Li, Yingxin Chen, Ruiyun Huang, Chujing Li, Xilin Ouyang, Huazhuo Feng, Hanqing Xu, Dezhi Liu, Zheng Dai, Juehua Zhu, Xinfeng Liu, Hongbing Chen and Yongjun Jiang

    Citation: BMC Neurology 2019 19:186

    Content type: Research article

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  20. Stroke is the second-leading global cause of death behind heart disease in 2013 and is a major cause of permanent disability. The burden of stroke in terms of mortality, morbidity and disability is increasing ...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:183

    Content type: Research article

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    The Retraction Note to this article has been published in BMC Neurology 2019 19:327

  21. Hypothalamic lesions, such as tumors and demyelinating diseases, reportedly cause abnormal sleepiness. However, stroke involving the hypothalamus has rarely been described. Here, we report a patient with infar...

    Authors: Takeo Matsubara, Keisuke Suzuki, Akiko Kawasaki, Masayuki Miyamoto, Madoka Okamura, Takashi Kanbayashi, Hidehiro Takekawa, Toshiki Nakamura, Yuji Watanabe, Masanori Matsubara and Koichi Hirata

    Citation: BMC Neurology 2019 19:182

    Content type: Case report

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  22. Optimizing thrombolytic therapy is vital for improving stroke outcomes. We aimed to develop standardized thrombolysis conditions to evaluate the efficacy of tenecteplase (TNK) compared to the current gold stan...

    Authors: Tobias Frühwald, Ulrich Gärtner, Nils Stöckmann, Jan-Henning Marxsen, Carolin Gramsch and Florian C. Roessler

    Citation: BMC Neurology 2019 19:181

    Content type: Research article

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  23. This study examined how intracranial large artery stenosis (ILAS), symptomatic and asymptomatic ILAS, and risk factors affect unfavorable outcome events after medical treatment in routine clinical practice.

    Authors: K. C. Chang, I. C. Chuang, Y. C. Huang, C. Y. Wu, W. C. Lin, Y. L. Kuo, T. H. Lee and S. J. Ryu

    Citation: BMC Neurology 2019 19:180

    Content type: Research article

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  24. B-mode and Color Doppler ultrasonography (CDUS) are the methods of choice for screening and determining the degree of Carotid artery stenosis. The evaluation of stenosis with calcification may be hampered by a...

    Authors: Estelle E. Seyman, Natan Bornstein, Eitan Auriel, Oren Cohen, Tania Nissel and Hen Hallevi

    Citation: BMC Neurology 2019 19:178

    Content type: Research article

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  25. Insulin resistance (IR) in relation to diabetes is a risk factor for ischemic stroke (IS), whereas less is known about non-diabetic IR and outcome after IS.

    Authors: Daniel Åberg, N. David Åberg, Katarina Jood, Lukas Holmegaard, Petra Redfors, Christian Blomstrand, Jörgen Isgaard, Christina Jern and Johan Svensson

    Citation: BMC Neurology 2019 19:177

    Content type: Research article

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  26. Elevated levels of plasma D-dimer increase the risk of ischemic stroke, stroke severity, and the progression of stroke status, but the association between plasma D-dimer level and functional outcome is unclear...

    Authors: Tao Yao, Bo-Lin Tian, Gang Li, Qin Cui, Cui-fang Wang, Qi Zhang, Bo Peng, Yan Gao, Yan-Qiang Zhan, Dan Hu, Lu Xu and Gao-Hua Wang

    Citation: BMC Neurology 2019 19:175

    Content type: Research article

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  27. The exact relationship between 25-hydroxyvitamin D [25(OH) D] levels and small vessel disease (SVD) are not clear in China. The aim of this study was to determine such the association between 25(OH) D and SVD ...

    Authors: Junzeng Si, Kuibao Li, Peiyan Shan and Junliang Yuan

    Citation: BMC Neurology 2019 19:164

    Content type: Research article

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  28. Patients with vertebrobasilar dolichoectasia usually have persistent hemodynamic abnormalities, and therefore, may bear an increased risk of stroke. This study aimed to identify risk factors for stroke recurre...

    Authors: Zhaoyao Chen, Shuai Zhang, Zhengze Dai, Xi Cheng, Minghua Wu, Qiliang Dai, Xinfeng Liu and Gelin Xu

    Citation: BMC Neurology 2019 19:163

    Content type: Research article

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  29. Intravenous thrombolysis has been recently introduced in Nepal for the management of acute ischemic stroke. Pre-hospital delay is one of the main reasons that hinder thrombolytic therapy. The objective of this...

    Authors: Gaurav Nepal, Jayant Kumar Yadav, Babin Basnet, Tirtha Man Shrestha, Ghanshyam Kharel and Rajeev Ojha

    Citation: BMC Neurology 2019 19:155

    Content type: Research article

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  30. Simultaneous cerebral and myocardial infarction is called cardiocerebral infarction (CCI), and is rarely encountered. Because of the narrow time window and complex pathophysiology, CCI is challenging to immedi...

    Authors: Soichiro Abe, Kanta Tanaka, Hiroshi Yamagami, Kazutaka Sonoda, Hiroya Hayashi, Shuichi Yoneda, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2019 19:152

    Content type: Case report

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  31. This study aimed to investigate the cerebral blood flow (CBF) and frontal lobe cognitive function in severe internal carotid artery (ICA) stenosis patients with different types of collateral circulation.

    Authors: Wei Wei, Xingyang Yi, Jianghai Ruan, Xiaodong Duan, Hua Luo and Zhiyu Lv

    Citation: BMC Neurology 2019 19:151

    Content type: Research article

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  32. Mechanical thrombectomy has been proven as a standard care for moderate to severe ischemic stroke with anterior large vessel occlusion (LVO); however, whether it is equally effective in mild ischemic stroke (M...

    Authors: Xian-Jin Shang, Zhong-Hua Shi, Cai-Feng He, Shuai Zhang, Yong-Jie Bai, Yong-Tao Guo, Bo Sun, Shun Li, Huai-Ming Wang, Zhi-Ming Zhou, Wen-Jie Zi and Xin-Feng Liu

    Citation: BMC Neurology 2019 19:150

    Content type: Research article

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  33. Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are c...

    Authors: A. Mengel, L. Ulm, B. Hotter, H. Harms, S. K. Piper, U. Grittner, J. Montaner, C. Meisel, A. Meisel and S. Hoffmann

    Citation: BMC Neurology 2019 19:148

    Content type: Research article

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  34. Triglycerides (TG)/high-density lipoprotein (HDL) cholesterol ratio is a marker of small/dense low-density lipoprotein particles, which are closely associated with various metabolic and vascular diseases. Howe...

    Authors: Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Hyuktae Kwon and Su-Min Jeong

    Citation: BMC Neurology 2019 19:147

    Content type: Research article

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  35. Heat stroke (HS) is a critical illness that can cause multiple organ dysfunction, including damage to the central nervous system (CNS), which can be life-threatening in severe cases. Brain lesions in patients ...

    Authors: Lizhi Cao, Juan Wang, Yaxuan Gao, Yumei Liang, Jinhua Yan, Yunhai Zhang, Mingqin Zhu, Tianfei Luo and Jiafeng Chen

    Citation: BMC Neurology 2019 19:133

    Content type: Case report

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  36. Mood disorder after stroke is common but drug and psychosocial treatments have been assessed with disappointing results. Preventing mood disorder from developing in the first place could be a better approach a...

    Authors: Kate Hill, Allan House, Peter Knapp, Carrie Wardhaugh, John Bamford and Andy Vail

    Citation: BMC Neurology 2019 19:128

    Content type: Research article

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  37. Immune cells are involved in all stages of acute ischaemic stroke (AIS) and possess both neuroprotective and neurodamaging properties. It has been suggested that immune system activation after stroke may be as...

    Authors: Neringa Jucevičiūtė, Paulius Mikužis and Renata Balnytė

    Citation: BMC Neurology 2019 19:127

    Content type: Research article

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  38. Fabry disease is rare, and the diagnosis is often delayed. Here, we describe a case of Fabry disease resulting in vasculopathy of the central nervous system. Magnetic resonance (MR) black-blood sequence (three...

    Authors: De-Zheng Kong, Ya-Hui Lian, Lin-Jing Wang, Chun-Mei Wang, Yang-Yang Meng and Hong-Wei Zhou

    Citation: BMC Neurology 2019 19:115

    Content type: Case report

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  39. Internal jugular vein stenosis (IJVS), characterized by a series of clinical manifestations, such as head and neck symptoms, visual and ear symptoms, as well as sleep disorder, has been receiving attention in ...

    Authors: Min Li, Yuan Sun, Chong Ching Chan, Chunqiu Fan, Xunming Ji and Ran Meng

    Citation: BMC Neurology 2019 19:112

    Content type: Case report

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  40. endovascular therapy (ET) is the standard of care for anterior circulation acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). The role of adjunctive intravenous thrombolysis (IVT) in these pat...

    Authors: Massimo Gamba, Nicola Gilberti, Enrico Premi, Angelo Costa, Michele Frigerio, Dikran Mardighian, Veronica Vergani, Raffaella Spezi, Ilenia Delrio, Andrea Morotti, Loris Poli, Valeria De Giuli, Filomena Caria, Alessandro Pezzini, Roberto Gasparotti, Alessandro Padovani…

    Citation: BMC Neurology 2019 19:103

    Content type: Research article

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  41. Exercise has failed to reduce falls in those with chronic stroke. A limitation of traditional exercise is that the motor responses needed to prevent a fall are not elicited (i.e. they lack processing specificity)...

    Authors: Jamie Pigman, Darcy S. Reisman, Ryan T. Pohlig, Tamara R. Wright and Jeremy R. Crenshaw

    Citation: BMC Neurology 2019 19:102

    Content type: Research article

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  42. A revised classification of cerebellar infarctions (CI) may uncover unrecognized associations with etiologic stroke subtypes. We hypothesized that obliquely oriented small cortical cerebellar infarction (SCCI)...

    Authors: Adrien Ter Schiphorst, Lavinia Tatu, Vincent Thijs, Christophe Demattei, Eric Thouvenot and Dimitri Renard

    Citation: BMC Neurology 2019 19:100

    Content type: Research article

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