Access, timing and frequency of very early stroke rehabilitation – insights from the Baden-Wuerttemberg stroke registry

While the precise timing and intensity of very early rehabilitation (VER) after stroke onset is still under discussion, its beneficial effect on functional disability is generally accepted. The recently publis...

Authors: Björn Reuter, Christoph Gumbinger, Tamara Sauer, Horst Wiethölter, Ingo Bruder, Curt Diehm, Peter A. Ringleb, Werner Hacke, Michael G. Hennerici and Rolf Kern

Self-management develops through doing of everyday activities—a longitudinal qualitative study of stroke survivors during two years post-stroke

A description of the complexity of the process of self-management and the way stroke survivors give meaning to their process of self-management post-stroke is lacking. This study explores how stroke survivors ...

Authors: Ton Satink, Staffan Josephsson, Jana Zajec, Edith H. C. Cup, Bert J. M. de Swart and Maria W. G. Nijhuis-van der Sanden

Is upper limb virtual reality training more intensive than conventional training for patients in the subacute phase after stroke? An analysis of treatment intensity and content

Virtual reality (VR) training is thought to improve upper limb (UL) motor function after stroke when utilizing intensive training with many repetitions. The purpose of this study was to compare intensity and c...

Authors: Iris Brunner, Jan Sture Skouen, Håkon Hofstad, Jörg Aßmuss, Frank Becker, Hanne Pallesen, Liselot Thijs and Geert Verheyden

Perceived ability to perform daily hand activities after stroke and associated factors: a cross-sectional study

Despite that disability of the upper extremity is common after stroke, there is limited knowledge how it influences self-perceived ability to perform daily hand activities. The aim of this study was to describ...

Authors: Elisabeth Ekstrand, Lars Rylander, Jan Lexell and Christina Brogårdh

The collateral circulation determines cortical infarct volume in anterior circulation ischemic stroke

Acute ischemic stroke (AIS) is a common neurological event that causes varying degrees of disability. AIS outcome varies considerably, from complete recovery to complete loss of tissue and function. This diver...

Authors: Estelle Seyman, Hilla Shaim, Shani Shenhar-Tsarfaty, Tali Jonash-Kimchi, Natan M. Bornstein and Hen Hallevi

Disappearance of treatment-resistant depression after damage to the orbitofrontal cortex and subgenual cingulate area: a case study

Although post-stroke depression is a well-characterized disorder, there is less understanding of how pre-existence of depression is affected by a stroke.

Authors: Michitaka Funayama, Motoichiro Kato and Masaru Mimura

Diagnosis of a subarachnoid hemorrhage with only mild symptoms using computed tomography in Japan

Japan is currently an aging society, with a huge proportion of elderly citizens. Consequently, the incidence and severity of subarachnoid hemorrhage (SAH) is predicted to increase in the future. Computed tomog...

Authors: Syuichi Tetsuka and Eiji Matsumoto

Kidney function is associated with severity of white matter hyperintensity in patients with acute ischemic stroke/TIA

Previous studies suggested the potential interactions between cerebrovascular diseases and impaired renal function. However, the relationship between renal function and white matter hyperintensity (WMH), marke...

Authors: Lixia Zong, Ming Yao, Jun Ni, Lixin Zhou, Jing Yuan, Bin Peng, Yi-Cheng Zhu and Liying Cui

Erratum to: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with lateral medullary syndrome: case report and literature review

Authors: Hiroto Nakano, Daisuke Yanase and Masahito Yamada

Primary aldosteronism in patients with acute stroke: prevalence and diagnosis during initial hospitalization

Hypertension is the prime risk factor for stroke, and primary aldosteronism (PA) is the most common cause of secondary hypertension. The prevalence of PA in stroke patients has never been reported. The aim of ...

Authors: Yosuke Miyaji, Yuichi Kawabata, Hideto Joki, Shunsuke Seki, Kentaro Mori, Tomoya Kamide, Akira Tamase, Hiroshi Shima, Motohiro Nomura, Yoshihisa Kitamura, Hirotatsu Nakaguchi, Taichi Minami, Tetsuji Tsunoda, Mayuko Sasaki, Masayo Yamada and Fumiaki Tanaka

Development of a new stroke scale in an emergency setting

Early identification of stroke is crucial to maximize early management benefits in emergency departments. This study aimed to develop and validate a new stroke recognition instrument for differentiating acute ...

Authors: Haifeng Mao, Peiyi Lin, Junrong Mo, Yunmei Li, Xiaohui Chen, Timothy H. Rainer and Huilin Jiang

Allopurinol and the risk of stroke in older adults receiving medicare

Previous studies of allopurinol and stroke risk have provided contradictory findings, ranging from a protective effect to an increased risk. Our objective was to assess whether allopurinol use is associated wi...

Authors: Jasvinder A. Singh and Shaohua Yu

Test-retest reliability and four-week changes in cardiopulmonary fitness in stroke patients: evaluation using a robotics-assisted tilt table

Exercise testing devices for evaluating cardiopulmonary fitness in patients with severe disability after stroke are lacking, but we have adapted a robotics-assisted tilt table (RATT) for cardiopulmonary exerci...

Authors: Jittima Saengsuwan, Lucia Berger, Corina Schuster-Amft, Tobias Nef and Kenneth J. Hunt

Comparison of the Chinese ischemic stroke subclassification and Trial of Org 10172 in acute stroke treatment systems in minor stroke

The underlying causes of minor stroke are difficult to assess. Here, we evaluate the reliability of the Chinese Ischemic Stroke Subclassification (CISS) system in patients with minor stroke, and compare it to ...

Authors: Sha Tan, Lei Zhang, Xiaoyu Chen, Yanqiang Wang, Yinyao Lin, Wei Cai, Yilong Shan, Wei Qiu, Xueqiang Hu and Zhengqi Lu

Association study of polymorphisms in the ABO gene with ischemic stroke in the Chinese population

Ischemic stroke is the main cause of mortality and disability in older people worldwide. Recently epidemiological studies indicate that ischemic stroke is a complex disorder with a strong genetic component. Ge...

Authors: Xiaoming Ling, Yansong Zheng, Jing Tao, Zhezhou Zheng and Lidian Chen

Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice

VE-cadherin is the chief constituent of endothelial adherens junctions. However, the role of VE-cadherin in the pathogenesis of cerebrovascular diseases including brain ischemia has not yet been investigated.

Authors: Karen Gertz, Golo Kronenberg, Ria Uhlemann, Vincent Prinz, Ruben Marquina, Monica Corada, Elisabetta Dejana and Matthias Endres

Early consciousness disorder in acute ischemic stroke: incidence, risk factors and outcome

Little is known about the incidence and risk factors of early consciousness disorder (ECD) in patients with acute ischemic stroke, or about how ECD may affect complications and outcomes.

Authors: Jie Li, Deren Wang, Wendan Tao, Wei Dong, Jing Zhang, Jie Yang and Ming Liu

What’s keeping people after stroke from walking outdoors to become physically active? A qualitative study, using an integrated biomedical and behavioral theory of functioning and disability

In general people after stroke do not meet the recommendations for physical activity to conduct a healthy lifestyle. Programs to stimulate walking activity to increase physical activity are based on the availa...

Authors: Jacqueline Outermans, Jan Pool, Ingrid van de Port, Japie Bakers and Harriet Wittink

Complications in the first week after stroke: a 10-year comparison

Complications after stroke have been associated with poor outcome. Modern stroke treatment might reduce the occurrence of complications. The aim of this study was to investigate whether the frequency and type ...

Authors: Martina Reiten Bovim, Torunn Askim, Stian Lydersen, Hild Fjærtoft and Bent Indredavik

Cerebral vasospasm and wernicke encephalopathy secondary to adult cyclic vomiting syndrome: the role of magnesium

Magnesium has a regulatory role in the excitability of cell membranes, and is also a cofactor in the phosphorylation of thiamine. Hypomagnesemia has been associated with coronary vasospasm, but its role in cer...

Authors: Álvaro Sánchez-Larsen, Tomás Segura, Susana García-Muñozguren, Javier Peinado-Ródenas, Joaquín Zamarro and Francisco Hernández-Fernández