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Cerebrovascular disease and stroke

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  2. The aim of this systematic review is to determine the epidemiological and etiological profiles, the influential factors of the prehospital delay, thrombolysis management, the acute and 3-month mortality rate a...

    Authors: Ahmed Kharbach, Majdouline Obtel, Laila Lahlou, Jehanne Aasfara, Nour Mekaoui and Rachid Razine

    Citation: BMC Neurology 2019 19:349

    Content type: Review

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  3. A fraction of patients with penetrating artery infarction (PAI) experience progressive motor deficit deterioration (PMD). We sought to investigate the role of high-sensitivity C-reactive protein (hs-CRP) at ad...

    Authors: Pengyu Gong, Yukai Liu, Ting Huang, Wenxiu Chen, Teng Jiang, Yachi Gong, Min Lu, Meng Wang, Yingdong Zhang, Xiaohao Zhang, Qiwen Deng and Junshan Zhou

    Citation: BMC Neurology 2019 19:346

    Content type: Research article

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  4. To systematically review and analyse the effects of Action Observation Training on adults and children with brain damage.

    Authors: Bianca Buchignani, Elena Beani, Valerie Pomeroy, Oriana Iacono, Elisa Sicola, Silvia Perazza, Eleonora Bieber, Hilde Feys, Katrijn Klingels, Giovanni Cioni and Giuseppina Sgandurra

    Citation: BMC Neurology 2019 19:344

    Content type: Research article

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  5. Admission hyperglycemia (HG) has been associated with worse outcomes among acute stroke patients. A better understanding and awareness of the potentially adverse influence of hyperglycemia on the clinical outc...

    Authors: Yared Zenebe Zewde, Abenet Tafesse Mengesha, Yeweynhareg Feleke Gebreyes and Halvor Naess

    Citation: BMC Neurology 2019 19:342

    Content type: Research article

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  7. The elongation of the styloid process is historically associated with two variants of the Eagle syndrome. The classic one, mainly characterized by pain and dysphagia, and the carotid variant characterized by p...

    Authors: Paolo Zamboni, Alba Scerrati, Erica Menegatti, Roberto Galeotti, Marcello Lapparelli, Luca Traina, Mirko Tessari, Andrea Ciorba, Pasquale De Bonis and Stefano Pelucchi

    Citation: BMC Neurology 2019 19:333

    Content type: Research article

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  8. Hospital-acquired infection (HAI) is a serious complication of neurosurgery. In recent years, the medical body has paid increasing attention to this issue.

    Authors: Jun Wang, Yuanyuan Ji, Lidan Jiang, Xia Zhao, Shaochen Guan, Piao Yang, Jie Yu, Yunyun Liu and Hongqi Zhang

    Citation: BMC Neurology 2019 19:332

    Content type: Research article

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  9. Spontaneous conus medullaris infarction is a rare disease. We describe two patients with spontaneous conus medullaris infarction presenting as acute cauda equina syndrome and their unique electromyography (EMG...

    Authors: Yi-Ching Weng, Shy-Chyi Chin, Yah-Yuan Wu and Hung-Chou Kuo

    Citation: BMC Neurology 2019 19:328

    Content type: Case report

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  10. Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle...

    Authors: Yang-Yang Meng, Le Dou, Chun-Mei Wang, De-Zheng Kong, Ying Wei, Li-Shan Wu, Yi Yang and Hong-Wei Zhou

    Citation: BMC Neurology 2019 19:321

    Content type: Case report

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  11. Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. ...

    Authors: Xuan Sun, Xu Tong, Feng Gao, Huiting Lao and Zhongrong Miao

    Citation: BMC Neurology 2019 19:315

    Content type: Research article

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  12. Vertebral artery dissection (VAD) may cause cerebral ischemia and impair quality of life (QOL) despite of good functional outcome. The aim of this study was the multimodal analysis of patient characteristics a...

    Authors: Rainer J. Strege, Reinhard Kiefer and Manfred Herrmann

    Citation: BMC Neurology 2019 19:312

    Content type: Research article

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  14. Treatment with anticoagulants, including direct oral anticoagulants (DOACs), should be considered for patients diagnosed with atrial fibrillation (AF) deemed at risk of ischaemic stroke. There are limited real...

    Authors: Yaqoob Bhat, Anand Dixit, Amit Mistri, Bhavini Patel, Sadat Haider Quoraishi and James Uprichard

    Citation: BMC Neurology 2019 19:306

    Content type: Study protocol

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  15. The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke is time dependent. Despite great effort, the median door-to-needle time (DNT) was 60 min at the United States stroke centers. We investig...

    Authors: Demi Tran, Zhu Zhu, Mohammad Shafie, Hermelinda Abcede, Dana Stradling and Wengui Yu

    Citation: BMC Neurology 2019 19:300

    Content type: Research article

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  16. Stroke-associated pneumonia (SAP) is a common complication of cerebrovascular disease. The A2DS2 score has been used to predict the risk of SAP. However, hyperglycemia is not included in this scale. The purpose o...

    Authors: Yang Li, Yu Zhang, Liansheng Ma, Xiaoyuan Niu and Junsen Chang

    Citation: BMC Neurology 2019 19:298

    Content type: Research article

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  17. A huge spherical intracranial mass can sometimes be misdiagnosed, due to the lack of typical radiographic features. Thrombosed giant intracranial aneurysms (GIAs) are an uncommon but still a possible different...

    Authors: Mehdi Chihi, Ramazan Jabbarli, Oliver Gembruch, Sarah Teuber-Hanselmann, Marvin Darkwah Oppong, Daniela Pierscianek, Alexander Radbruch, Martin Glas, Mark Stettner and Ulrich Sure

    Citation: BMC Neurology 2019 19:297

    Content type: Case report

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  19. Transient ischemic attack (TIA) patients are at high risk of recurrent vascular events; timely management can reduce that risk by 70%. The Protocol-guided Rapid Evaluation of Veterans Experiencing New Transien...

    Authors: D. M. Bravata, L. J. Myers, B. Homoya, E. J. Miech, N. A. Rattray, A. J. Perkins, Y. Zhang, J. Ferguson, J. Myers, A. J. Cheatham, L. Murphy, B. Giacherio, M. Kumar, E. Cheng, D. A. Levine, J. J. Sico…

    Citation: BMC Neurology 2019 19:294

    Content type: Study protocol

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  20. Neurological disorders are an economic and public health burden which requires efficient and adequate medical resources. Currently, little is known about the status of the quality of neurological care services...

    Authors: Jun-Fang Zhang, Meng-Yao Qiu, Yu-Lei Zhang, Xi-Xi Wang, Guo-Ping Wang, Yu Geng, Ke-Zhong Zhang, Kan Fang and Yun-Cheng Wu

    Citation: BMC Neurology 2019 19:293

    Content type: Research article

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  21. Mutations of cyclooxygenase gene (COX gene) may increase the susceptibility of ischemic stroke. We investigated five variants (rs5788, rs1330344, rs3842788, rs20417, and rs689466) of two COX genes in order to ...

    Authors: Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen and Li He

    Citation: BMC Neurology 2019 19:291

    Content type: Research article

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  22. Ischemia-reperfusion (I/R)-induced vascular dysfunction is the main factor to acute ischemic stroke. Sirt3 is one of the sirtuin family members, which plays an important role in the development of neurological...

    Authors: Zhenzhen Zhao, Xiaoxiu Zhang, Yuanqiang Dai, Ke Pan, Yu Deng, Yan Meng and Tao Xu

    Citation: BMC Neurology 2019 19:289

    Content type: Research article

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  23. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of unknown cause involving the brain and accompanied by prominent eosinophilia. Intracardiac thrombosis is a major cardiac com...

    Authors: Kenichiro Hira, Hideki Shimura, Riyu Kamata, Masashi Takanashi, Akane Hashizume, Keiji Takahashi, Mizuho Sugiyama, Hiroshi Izumi, Nobutaka Hattori and Takao Urabe

    Citation: BMC Neurology 2019 19:288

    Content type: Case report

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  24. Capsular warning syndrome (CWS) is a rare clinical syndrome, which is defined as a recurrent transient lacunar syndrome. The mechanism and clinical management of CWS remain unclear. The aim of the study was to...

    Authors: Lanying He, Ronghua Xu, Jian Wang, Lili Zhang, Lijuan Zhang, Fangfang Zhou and Weiwei Dong

    Citation: BMC Neurology 2019 19:285

    Content type: Research article

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  25. As health behavior varies with increasing age, we aimed to examine the potential barriers in calling emergency medical services (EMS) after recognizing a stroke among 40–74- and 75–99-year-old adults.

    Authors: Shengde Li, Li-Ying Cui, Craig Anderson, Chunpeng Gao, Chengdong Yu, Guangliang Shan, Longde Wang and Bin Peng

    Citation: BMC Neurology 2019 19:283

    Content type: Research article

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  26. Diagnosing dysphagia in acute stroke patients is crucial, as this comorbidity determines morbidity and mortality; we therefore investigated the impact of flexible nasolaryngeal endoscopy (FEES) in acute stroke...

    Authors: Tobias Braun, Martin Juenemann, Maxime Viard, Marco Meyer, Iris Reuter, Mario Prosiegel, Manfred Kaps and Christian Tanislav

    Citation: BMC Neurology 2019 19:282

    Content type: Research article

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  27. Cerebral infarction occurs when the arteries to brain are obstructed, and motor impairment contralateral to responsible lesion is commonly recognized. Few studies have profiled the characteristics of cases wit...

    Authors: Zhe-Ren Tan, Chen Zhang and Fa-Fa Tian

    Citation: BMC Neurology 2019 19:279

    Content type: Research article

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  28. Early supported discharge (ESD) has been shown to be efficient and safe as part of the stroke care pathway. The best results have been seen with a multidisciplinary team and after mild to moderate stroke. Howe...

    Authors: Lena Rafsten, Anna Danielsson, Asa Nordin, Ann Björkdahl, Asa Lundgren-Nilsson, Maria E. H. Larsson and Katharina S. Sunnerhagen

    Citation: BMC Neurology 2019 19:277

    Content type: Research article

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  29. Internal carotid artery dissection has been well recognized as a major cause of ischaemic stroke in young and middle-aged adults. However, internal carotid artery dissection induced hypoglossal nerve palsy has...

    Authors: Zhaoyao Chen, Jun Yuan, Hui Li, Cuiping Yuan, Kailin Yin, Sen Liang, Pengfei Li and Minghua Wu

    Citation: BMC Neurology 2019 19:276

    Content type: Case report

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  30. Early prediction of unfavorable outcome after ischemic stroke is of great significance to the clinical and therapeutic management. A nomogram is a better visual tool than earlier models and prognostic scores t...

    Authors: Chao Sun, Xiang Li, Baili Song, Xiangliang Chen, Linda Nyame, Yukai Liu, Dan Tang, Mako Ibrahim, Zheng Zhao, Chao Liu, Miao Yan, Xiding Pan, Jie Yang, Junshan Zhou and Jianjun Zou

    Citation: BMC Neurology 2019 19:274

    Content type: Research article

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  31. Patients with acute ischemic stroke (AIS) often experience low serum free triiodothyronine (FT3), but the association of low FT3 with stroke severity, subtype and prognosis has not yet been thoroughly studied,...

    Authors: Shanchao Zhang, Xia Zhao, Shan Xu, Jing Yuan, Zhihua Si, Yang Yang, Shan Qiao, Xuxu Xu and Aihua Wang

    Citation: BMC Neurology 2019 19:272

    Content type: Research article

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  32. To study the association of caregiver factors and stroke patient factors with rehospitalizations over the first 3 months and subsequent 3–12 months post-stroke in Singapore.

    Authors: Shilpa Tyagi, Gerald C. H. Koh, Nan Luo, Kelvin B. Tan, Helen Hoenig, David B. Matchar, Joanne Yoong, Angelique Chan, Kim En Lee, N. Venketasubramanian, Edward Menon, Kin Ming Chan, Deidre Anne De Silva, Philip Yap, Boon Yeow Tan, Effie Chew…

    Citation: BMC Neurology 2019 19:267

    Content type: Research article

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  33. Intravenous thrombolysis (IVT) plays a prominent role in the treatment of acute ischemic stroke (AIS). The sooner IVT is administered, the higher the odds of a good outcome. Therefore, registering the in-hospi...

    Authors: Laurien S. Kuhrij, Perla J. Marang-van de Mheen, Renske M. van den Berg-Vos, Frank-Erik de Leeuw and Paul J. Nederkoorn

    Citation: BMC Neurology 2019 19:265

    Content type: Research article

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  34. Failing to recognise the signs and symptoms of subarachnoid haemorrhage (SAH) causes diagnostic delay and may result in poorer outcomes. We report a rare case of SAH secondary to a vertebral artery dissection ...

    Authors: Lloyd Steele, Muhammad Hasan Raza, Richard Perry, Neil Rane and Sophie J. Camp

    Citation: BMC Neurology 2019 19:262

    Content type: Case report

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  35. The aim of this study was to evaluate the correlation between significant asymptomatic carotid artery stenosis (ACAS) and severity of peripheral arterial occlusive disease (PAOD) in the lower limb, and to inve...

    Authors: Zhongjie Pan, Ruitao Wang, Li Li and Hua Zhang

    Citation: BMC Neurology 2019 19:259

    Content type: Research article

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  37. Elevated blood pressure (BP) at emergency department (ED) presentation and advancing age have been associated with risk of ischemic stroke; however, the relationship between BP, age, and transient ischemic att...

    Authors: Andrew M. Penn, Nicole S. Croteau, Kristine Votova, Colin Sedgwick, Robert F. Balshaw, Shelagh B. Coutts, Melanie Penn, Kaitlin Blackwood, Maximilian B. Bibok, Viera Saly, Janka Hegedus, Amy Y. X. Yu, Charlotte Zerna, Evgenia Klourfeld and Mary L. Lesperance

    Citation: BMC Neurology 2019 19:251

    Content type: Research article

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  38. The purpose of this study was to report our preliminary experience of stent-assisted coiling (SAC) of wide-necked intracranial aneurysms with a single microcatheter in patients with parent arteries that were s...

    Authors: Keun Young Park, Chang Ki Jang, Jae Whan Lee, Dong Joon Kim, Byung Moon Kim and Joonho Chung

    Citation: BMC Neurology 2019 19:245

    Content type: Technical advance

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  39. Atrial fibrillation (AF) is a common cause of cerebral infarction, which could lead to endothelial dysfunction, increased reactive oxygen species (ROS) and oxidized low density lipoprotein (Ox-LDL).AF is assoc...

    Authors: Lanying He, Ronghua Xu, Jian Wang, Lili Zhang, Lijuan Zhang, Wang Zhao and Weiwei Dong

    Citation: BMC Neurology 2019 19:240

    Content type: Research article

    Published on:

  40. Previously there have been found higher circulating malondialdehyde levels during the first week of ischemic stroke in patients with worst neurological functional outcome, and at moment of ischemic stroke in n...

    Authors: Leonardo Lorente, María M. Martín, Pedro Abreu-González, Rafael Sabatel, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez and Victor García-Marín

    Citation: BMC Neurology 2019 19:238

    Content type: Research article

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  41. Brain ischemia activates the parasympathetic cholinergic pathway in animal models of human disease. However, it remains unknown whether activation of the cholinergic pathway impacts immune defenses and disease...

    Authors: Meng Yuan, Bin Han, Yiping Xia, Ye Liu, Chunyang Wang and Chao Zhang

    Citation: BMC Neurology 2019 19:236

    Content type: Research article

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  42. Radiation therapy can cause cerebral arteriopahty, resulting in ischemic stroke. We document late-delayed cerebral arteriopathy by high-resolution magnetic resonance imaging (HR-MRI) in a middle aged man who h...

    Authors: Huan Chen, Xiuhua Li, Xiaoyu Zhang, Wenjuan Xu, Fei Mao, Mengxin Bao and Meijia Zhu

    Citation: BMC Neurology 2019 19:232

    Content type: Case report

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  43. Endovascular treatment (EVT) is advocated for acute ischaemic stroke with large-vessel occlusion (LVO), but perioperative periods are challenging. This study investigated the relationship between post-EVT shor...

    Authors: Tianli Zhang, Xiaolong Wang, Chao Wen, Feng Zhou, Shengwei Gao, Xiaodong Zhang, Shiqin Lin, Jing Shi and Weirong Li

    Citation: BMC Neurology 2019 19:228

    Content type: Research article

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  44. Due to improvements in both the quality and availability of intracranial imaging as well as the evolution of surgical and endovascular techniques during the last decade, the number of treatments of unruptured ...

    Authors: Christin Campe, Jens Neumann, I. Erol Sandalcioglu, Ali Rashidi and Michael Luchtmann

    Citation: BMC Neurology 2019 19:226

    Content type: Case report

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  45. Self-rated health (SRH) allows for comparison and identification of the health status of various populations. The aim of this study was to conduct a systematic review of the literature to expand the understand...

    Authors: Érika de Freitas Araújo, Ramon Távora Viana, Luci Fuscaldi Teixeira-Salmela, Lidiane Andrea Oliveira Lima and Christina Danielli Coelho de Morais Faria

    Citation: BMC Neurology 2019 19:221

    Content type: Research article

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  46. Stroke patients are often affected by long-term disabilities with needs concerning social issues. There is relatively little consideration of social recovery of patients and the support required to return to w...

    Authors: Sophie Lehnerer, Benjamin Hotter, Inken Padberg, Petra Knispel, Dike Remstedt, Andrea Liebenau, Ulrike Grittner, Ian Wellwood and Andreas Meisel

    Citation: BMC Neurology 2019 19:220

    Content type: Research article

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  47. The global burden of stroke epidemiology is changing rapidly. Over the 1990–2013 periods, there was a significant increase in the absolute number of deaths and incident events of stroke. The burden of stroke v...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:213

    Content type: Research article

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  49. Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei pro...

    Authors: Yanfeng Zhou, Shijiao Yan, Xingyue Song, Yanhong Gong, Wenzhen Li, Mengdie Wang, Xiaoxv Yin, Bo Hu and Zuxun Lu

    Citation: BMC Neurology 2019 19:202

    Content type: Research article

    Published on:

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