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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Content type: Research article

    Previous studies suggested the potential interactions between cerebrovascular diseases and impaired renal function. However, the relationship between renal function and white matter hyperintensity (WMH), marke...

    Authors: Lixia Zong, Ming Yao, Jun Ni, Lixin Zhou, Jing Yuan, Bin Peng, Yi-Cheng Zhu and Liying Cui

    Citation: BMC Neurology 2016 16:193

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  2. Content type: Research article

    Hypertension is the prime risk factor for stroke, and primary aldosteronism (PA) is the most common cause of secondary hypertension. The prevalence of PA in stroke patients has never been reported. The aim of ...

    Authors: Yosuke Miyaji, Yuichi Kawabata, Hideto Joki, Shunsuke Seki, Kentaro Mori, Tomoya Kamide, Akira Tamase, Hiroshi Shima, Motohiro Nomura, Yoshihisa Kitamura, Hirotatsu Nakaguchi, Taichi Minami, Tetsuji Tsunoda, Mayuko Sasaki, Masayo Yamada and Fumiaki Tanaka

    Citation: BMC Neurology 2016 16:177

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  3. Content type: Research article

    Early identification of stroke is crucial to maximize early management benefits in emergency departments. This study aimed to develop and validate a new stroke recognition instrument for differentiating acute ...

    Authors: Haifeng Mao, Peiyi Lin, Junrong Mo, Yunmei Li, Xiaohui Chen, Timothy H. Rainer and Huilin Jiang

    Citation: BMC Neurology 2016 16:168

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  4. Content type: Research article

    Exercise testing devices for evaluating cardiopulmonary fitness in patients with severe disability after stroke are lacking, but we have adapted a robotics-assisted tilt table (RATT) for cardiopulmonary exerci...

    Authors: Jittima Saengsuwan, Lucia Berger, Corina Schuster-Amft, Tobias Nef and Kenneth J. Hunt

    Citation: BMC Neurology 2016 16:163

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  5. Content type: Research article

    The underlying causes of minor stroke are difficult to assess. Here, we evaluate the reliability of the Chinese Ischemic Stroke Subclassification (CISS) system in patients with minor stroke, and compare it to ...

    Authors: Sha Tan, Lei Zhang, Xiaoyu Chen, Yanqiang Wang, Yinyao Lin, Wei Cai, Yilong Shan, Wei Qiu, Xueqiang Hu and Zhengqi Lu

    Citation: BMC Neurology 2016 16:162

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  6. Content type: Research article

    Ischemic stroke is the main cause of mortality and disability in older people worldwide. Recently epidemiological studies indicate that ischemic stroke is a complex disorder with a strong genetic component. Ge...

    Authors: Xiaoming Ling, Yansong Zheng, Jing Tao, Zhezhou Zheng and Lidian Chen

    Citation: BMC Neurology 2016 16:146

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  7. Content type: Research article

    VE-cadherin is the chief constituent of endothelial adherens junctions. However, the role of VE-cadherin in the pathogenesis of cerebrovascular diseases including brain ischemia has not yet been investigated.

    Authors: Karen Gertz, Golo Kronenberg, Ria Uhlemann, Vincent Prinz, Ruben Marquina, Monica Corada, Elisabetta Dejana and Matthias Endres

    Citation: BMC Neurology 2016 16:144

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  8. Content type: Research article

    In general people after stroke do not meet the recommendations for physical activity to conduct a healthy lifestyle. Programs to stimulate walking activity to increase physical activity are based on the availa...

    Authors: Jacqueline Outermans, Jan Pool, Ingrid van de Port, Japie Bakers and Harriet Wittink

    Citation: BMC Neurology 2016 16:137

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  9. Content type: Case report

    Magnesium has a regulatory role in the excitability of cell membranes, and is also a cofactor in the phosphorylation of thiamine. Hypomagnesemia has been associated with coronary vasospasm, but its role in cer...

    Authors: Álvaro Sánchez-Larsen, Tomás Segura, Susana García-Muñozguren, Javier Peinado-Ródenas, Joaquín Zamarro and Francisco Hernández-Fernández

    Citation: BMC Neurology 2016 16:135

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  10. Content type: Research article

    Complications after stroke have been associated with poor outcome. Modern stroke treatment might reduce the occurrence of complications. The aim of this study was to investigate whether the frequency and type ...

    Authors: Martina Reiten Bovim, Torunn Askim, Stian Lydersen, Hild Fjærtoft and Bent Indredavik

    Citation: BMC Neurology 2016 16:133

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  11. Content type: Case report

    Volume isotropic turbo spin-echo acquisition (VISTA) is a new method similar to the 3D black-blood imaging method that enables visualization of a intramural hematoma. T1-VISTA has recently been applied in the ...

    Authors: Koji Ishitsuka, Yusuke Sakaki, Shota Sakai, Takeshi Uwatoko, Hitoshi Aibe, Tetsuro Ago, Takanari Kitazono and Hiroshi Sugimori

    Citation: BMC Neurology 2016 16:121

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  12. Content type: Case report

    Only one case of syndrome of inappropriate secretion of antidiuretic hormone with lateral medullary syndrome has been reported so far. We report a case of lateral medullary syndrome showing syndrome of inappro...

    Authors: Hiroro Nakano, Daisuke Yanase and Masahito Yamada

    Citation: BMC Neurology 2016 16:119

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    The Erratum to this article has been published in BMC Neurology 2016 16:192

  13. Content type: Research article

    The clinical significance of vertebral artery (VA) hypoplasia is under discussion. The aim of this retrospective study is to evaluate a hypothesis of a possible causal link between VA hypoplasia (VAH) and the ...

    Authors: Virginija Gaigalaite, Augenijus Vilimas, Violeta Ozeraitiene, Jurate Dementaviciene, Ricardas Janilionis, Danute Kalibatiene and Saulius Rocka

    Citation: BMC Neurology 2016 16:118

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  14. Content type: Research article

    Around two thirds stroke patients may suffer from vascular cognitive impairment (VCI). Our previous study has validated the NINDS-CSN harmonization standard for VCI diagnosis in Chinese. In this study, we aime...

    Authors: Xiangliang Chen, Lihui Duan, Yunfei Han, Ling Tian, Qiliang Dai, Shang Wang, Ying Lin, Yunyun Xiong and Xinfeng Liu

    Citation: BMC Neurology 2016 16:115

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  15. Content type: Research article

    This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB).

    Authors: Gwang Sil Kim, Jae-Sun Uhm, Tae-Hoon Kim, Hancheol Lee, Junbeom Park, Jin-Kyu Park, Boyoung Joung, Hui-Nam Pak and Moon-Hyoung Lee

    Citation: BMC Neurology 2016 16:113

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  16. Content type: Research article

    The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of d...

    Authors: Trevor Sughrue, Michael A. Swiernik, Yang Huang and James P. Brody

    Citation: BMC Neurology 2016 16:112

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  17. Content type: Research article

    The prognostic influence of hyperglycemia in acute stroke has been well established. While in cortical stroke there is a strong association between hyperglycemia and poor outcome, this relation is less clear i...

    Authors: Irene Miedema, Gert-Jan Luijckx, Raf Brouns, Jacques De Keyser and Maarten Uyttenboogaart

    Citation: BMC Neurology 2016 16:104

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  18. Content type: Research article

    Transorbital sonography (TOS) has been proven to be able to non-invasively detect elevated intracranial pressure. In this condition TOS shows an increase in optic nerve sheath diameter (ONSD). It has been sugg...

    Authors: Piergiorgio Lochner, Francesco Brigo, Maria Luisa Zedde, Sandro Sanguigni, Lorenzo Coppo, Raffaele Nardone, Andrea Naldi, Daniele Sola and Erwin Stolz

    Citation: BMC Neurology 2016 16:85

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    The Erratum to this article has been published in BMC Neurology 2016 16:94

  19. Content type: Research article

    Living alone is associated with increased mortality after myocardial infarction but little data is available about whether this applies to prognosis after stroke. We aimed to examine the association between li...

    Authors: Petra Redfors, Daniella Isaksén, Georgios Lappas, Christian Blomstrand, Annika Rosengren, Katarina Jood and Christina Jern

    Citation: BMC Neurology 2016 16:80

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  20. Content type: Case report

    Limb-shaking transient ischemic attack (TIA) is a well-recognized, but rare observation in contralateral carotid steno-occlusive disease. Consequently, most clinicians have not had the chance to witness an att...

    Authors: Sverre Rosenbaum, Christian Ovesen, Nancy Futrell and Derk W. Krieger

    Citation: BMC Neurology 2016 16:78

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  21. Content type: Research article

    In recent randomized controlled trials (RCTs) intra-arterial treatment (IAT) has been proven effective and safe for patients with acute ischemic stroke (AIS). So far, there seemed to be no interaction between ...

    Authors: Debbie Beumer, Anouk D. Rozeman, Geert J. Lycklama à Nijeholt, Patrick A. Brouwer, Sjoerd F. M. Jenniskens, Ale Algra, Jelis Boiten, Wouter Schonewille, Robert J. van Oostenbrugge, Diederik W. J. Dippel and Wim H. van Zwam

    Citation: BMC Neurology 2016 16:68

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  22. Content type: Study protocol

    Cognitive impairment and neuropsychiatric syndromes, like depression and apathy, are frequent residual consequences of stroke. These have a large impact on quality of life and long-term prognosis. Several fact...

    Authors: Elles Douven, Syenna H. J. Schievink, Frans R. J. Verhey, Robert J. van Oostenbrugge, Pauline Aalten, Julie Staals and Sebastian Köhler

    Citation: BMC Neurology 2016 16:65

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  23. Content type: Research article

    The purpose of this study is to determine whether intracerebral hemorrhage and subarachnoid hemorrhage have different incidence patterns based on monthly variations in meteorological and air pollution paramete...

    Authors: Myung-Hoon Han, Hyeong-Joong Yi, Yong Ko, Young-Soo Kim and Young-Jun Lee

    Citation: BMC Neurology 2016 16:59

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  24. Content type: Research article

    Intravenous thrombolytic therapy after ischaemic stroke significantly reduces mortality and morbidity. Actual thrombolysis rates are disappointingly low in many western countries. It has been suggested that hi...

    Authors: S. Scherf, M. Limburg, R. Wimmers, I. Middelkoop and H. Lingsma

    Citation: BMC Neurology 2016 16:53

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  25. Content type: Research article

    Carotid artery stenosis is a frequent cause of ischemic stroke. While any degree of stenosis can cause embolic stroke, a higher degree of stenosis can also cause hemodynamic infarction. The hemodynamic effect ...

    Authors: Sibu Mundiyanapurath, Peter Arthur Ringleb, Sascha Diatschuk, Oliver Eidel, Sina Burth, Ralf Floca, Markus Möhlenbruch, Wolfgang Wick, Martin Bendszus and Alexander Radbruch

    Citation: BMC Neurology 2016 16:50

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  26. Content type: Research article

    The predictive ability of National Institute of Neurological Disease and Stroke-Canadian Stroke Network (NINDS-CSN) 5-minute protocol and Montreal Cognitive Assessment (MoCA) administered sub-acutely and at th...

    Authors: YanHong Dong, Jing Xu, Bernard Poon-Lap Chan, Raymond Chee Seong Seet, Narayanaswamy Venketasubramanian, Hock Luen Teoh, Vijay Kumar Sharma and Christopher Li-Hsian Chen

    Citation: BMC Neurology 2016 16:46

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  27. Content type: Study protocol

    Sitting ability and function are commonly impaired after stroke. Balance training has been shown to be helpful, but abundant repetitions are required for optimal recovery and patients must be motivated to perf...

    Authors: L. Sheehy, A. Taillon-Hobson, H. Sveistrup, M. Bilodeau, D. Fergusson, D. Levac and H. Finestone

    Citation: BMC Neurology 2016 16:42

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  28. Content type: Case report

    Internal carotid artery (ICA) occlusion mainly manifests as ischemia of the anterior circulation. There are very few reports of ICA occlusion manifesting as only ischemia of the posterior circulation related t...

    Authors: Ryo Hiramatsu, Hiroyuki Ohnishi, Shinji Kawabata, Shigeru Miyachi and Toshihiko Kuroiwa

    Citation: BMC Neurology 2016 16:41

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  29. Content type: Research article

    Collateral pathways are important in maintaining adequate cerebral blood flow in patients with carotid stenosis. We aimed to evaluate the hemodynamic patterns in relation to carotid stenosis in acute stroke pa...

    Authors: Hui Fang, Bo Song, Bo Cheng, Ka Sing Wong, Yu Ming Xu, Stella Sin Yee Ho and Xiang Yan Chen

    Citation: BMC Neurology 2016 16:39

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  30. Content type: Research article

    Total cholesterol is a well-documented risk factor for coronary disease. Previous studies have shown that high total cholesterol level is associated with better stroke outcomes, but the association of low tota...

    Authors: Wenjuan Zhao, Zhongping An, Yan Hong, Guanen Zhou, Jingjing Guo, Yongli Zhang, Yuanju Yang, Xianjia Ning and Jinghua Wang

    Citation: BMC Neurology 2016 16:36

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  31. Content type: Research article

    To investigate if initial blood pressure (BP) on admission is associated with stroke severity and predictive of admission costs and one-year-outcome in acute ischemic (IS) and hemorrhagic stroke (HS).

    Authors: Chi-Hung Liu, Yi-Chia Wei, Jr-Rung Lin, Chien-Hung Chang, Ting-Yu Chang, Kuo-Lun Huang, Yeu-Jhy Chang, Shan-Jin Ryu, Leng-Chieh Lin and Tsong-Hai Lee

    Citation: BMC Neurology 2016 16:27

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  32. Content type: Research article

    Convalescent rehabilitation wards assist stroke patients in acquiring skills for activities of daily living to increase the likelihood of home discharge. However, an improvement in activities of daily living d...

    Authors: Shinichiro Maeshima, Sayaka Okamoto, Hideto Okazaki, Shiho Mizuno, Naoki Asano, Hirofumi Maeda, Mitsuko Masaki, Hiroshi Matsuo, Tetsuya Tsunoda and Shigeru Sonoda

    Citation: BMC Neurology 2016 16:16

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  33. Content type: Research article

    The relationship between the apolipoprotein E (APOE) polymorphism and intracranial aneurysms has previously only been studied in Russia and Japan but not in Chinese populations. The purpose of this study was to i...

    Authors: Hao Liu, Ping Mao, Changhou Xie, Wanfu Xie, Maode Wang and Haitao Jiang

    Citation: BMC Neurology 2016 16:14

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  34. Content type: Case report

    Moyamoya syndrome is a vasculopathy characterised by progressive occlusion of the cerebral arteries resulting in the development of abnormal collateral circulation. To diagnose this syndrome, imaging of the ce...

    Authors: Tobias Braun, Martin Juenemann, Dursun Gündüz, Stefanie Schmetsdorf, Florian Roessler, Astrid Grams, Carolin Gramsch and Christian Tanislav

    Citation: BMC Neurology 2015 15:263

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  35. Content type: Research article

    The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry’s disease (FD) as a possible cause to check up. We ai...

    Authors: Laura Fancellu, Walter Borsini, Ilaria Romani, Angelo Pirisi, Giovanni Andrea Deiana, Elia Sechi, Pietro Emiliano Doneddu, Anna Laura Rassu, Rita Demurtas, Anna Scarabotto, Pamela Cassini, Eloisa Arbustini and GianPietro Sechi

    Citation: BMC Neurology 2015 15:256

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  36. Content type: Research article

    Stroke recurrence and disability in patients with a minor stroke is one of the most depressing medical situations. In this study, we aimed to identify which factors were associated with adverse outcomes of a m...

    Authors: Lingyun Wu, Anxin Wang, Xianwei Wang, Xingquan Zhao, Chunxue Wang, Liping Liu, Huaguang Zheng, Yongjun Wang, Yibin Cao and Yilong Wang

    Citation: BMC Neurology 2015 15:253

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  37. Content type: Case report

    Non-invasive brain stimulation-related seizures or syncopal events are rare. However, we report on a syncopal event in a healthy female during a transcranial magnetic stimulation single-pulse testing session.

    Authors: Bernadette T. Gillick, Tonya Rich, Mo Chen and Gregg D. Meekins

    Citation: BMC Neurology 2015 15:248

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  38. Content type: Study protocol

    Intravenous thrombolysis (IVT) with (recombinant) tissue plasminogen activator is an effective treatment in acute ischemic stroke. However, IVT is contraindicated when blood pressure is above 185/110 mmHg, bec...

    Authors: T. P. Zonneveld, A. Algra, D. W. J. Dippel, L. J. Kappelle, R. J. van Oostenbrugge, Y. B. W. E. M. Roos, M. J. Wermer, H. B. van der Worp, P. J. Nederkoorn and N. D. Kruyt

    Citation: BMC Neurology 2015 15:241

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  39. Content type: Research article

    An Early Supported Discharge (ESD) and rehabilitation from a coordinated team in the home environment is recommended in several high-income countries for patients with mild to moderate symptoms after stroke. R...

    Authors: Åsa Nordin, Katharina S. Sunnerhagen and Åsa B. Axelsson

    Citation: BMC Neurology 2015 15:235

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  40. Content type: Case report

    Studies on the role of cold agglutinins in the pathogenesis of acute ischemic stroke are scarce. We present a case of an elderly man with acute cerebral infarction probably due to cold agglutinin disease.

    Authors: Haiqiang Jin, Wei Sun, Yongan Sun, Yining Huang and Yunchuang Sun

    Citation: BMC Neurology 2015 15:222

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  41. Content type: Study protocol

    An effective diagnostic work-up in hospitalized patients with acute ischemic stroke is vital to optimize secondary stroke prevention. The HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) study aims to...

    Authors: Karl Georg Haeusler, Ulrike Grittner, Jochen B. Fiebach, Matthias Endres, Thomas Krause and Christian H. Nolte

    Citation: BMC Neurology 2015 15:213

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