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Cerebrovascular disease and stroke

Section edited by Szatmari Szabolcs

This section is dedicated to covering all aspects of stroke and cerebrovascular diseases. Topics of interest include, but are not limited to, ischemic stroke, spontaneous intracranial bleeding, sinus thrombosis, carotid or vertebral artery disease, cerebrovascular physiology, and neuroimaging related to cerebrovascular diseases.

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  1. Content type: Research article

    Deep-vein thrombosis (DVT) and pulmonary embolism (PE) are frequent and life-threatening complications of ischemic stroke. We evaluated rates of symptomatic DVT/PE, and of in-hospital and post-discharge thromb...

    Authors: Alpesh N Amin, Jay Lin, Stephen Thompson and Daniel Wiederkehr

    Citation: BMC Neurology 2013 13:17

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  2. Content type: Study protocol

    Patients with recent stroke or TIA are at high risk for new vascular events. Several evidence based strategies in secondary prevention of stroke are available but frequently underused. Support programs with mu...

    Authors: Stefanie Leistner, Georg Michelson, Inga Laumeier, Michael Ahmadi, Maureen Smyth, Gabriele Nieweler, Wolfram Doehner, Jan Sobesky, Jochen B Fiebach, Peter Marx, Otto Busse, Friedrich Köhler, Holger Poppert, Martin LJ Wimmer, Thomas Knoll, Paul Von Weitzel-Mudersbach…

    Citation: BMC Neurology 2013 13:11

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  3. Content type: Research article

    Jugular venous reflux (JVR) has been reported to cause cough syncope via retrograde-transmitted venous hypertension and consequently decreased cerebral blood flow (CBF). Unmatched frequencies of JVR and cough ...

    Authors: Chih-Ping Chung, Chun-Yu Cheng, Robert Zivadinov, Wei-Chih Chen, Wen-Yung Sheng, Yu-Chin Lee, Han-Hwa Hu, Hung-Yi Hsu and Kuang-Yao Yang

    Citation: BMC Neurology 2013 13:9

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  4. Content type: Case report

    POLG1 mutations have been associated with MELAS-like phenotypes. However given several clinical differences it is unknown whether POLG1 mutations are possible causes of MELAS or give raise to a distinct clinical...

    Authors: Antonella Cheldi, Dario Ronchi, Andreina Bordoni, Bianca Bordo, Silvia Lanfranconi, Maria Grazia Bellotti, Stefania Corti, Valeria Lucchini, Monica Sciacco, Maurizio Moggio, Pierluigi Baron, Giacomo Pietro Comi, Antonio Colombo and Anna Bersano

    Citation: BMC Neurology 2013 13:8

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  5. Content type: Research article

    Evidence about whether white blood cell (WBC) or its subtypes can act as a biomarker to predict the ischemic stroke events in the general population is scanty, particularly in Asian populations. The aim of thi...

    Authors: Tzy-Haw Wu, Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen and Yuan-Teh Lee

    Citation: BMC Neurology 2013 13:7

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  6. Content type: Study protocol

    Residual disability after stroke is substantial; 65% of patients at 6 months are unable to incorporate the impaired upper extremity into daily activities. Task-oriented training programs are rapidly being adop...

    Authors: Carolee J Winstein, Steven L Wolf, Alexander W Dromerick, Christianne J Lane, Monica A Nelsen, Rebecca Lewthwaite, Sarah Blanton, Charro Scott, Aimee Reiss, Steven Yong Cen, Rahsaan Holley and Stanley P Azen

    Citation: BMC Neurology 2013 13:5

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  7. Content type: Research article

    Responsiveness refers to a measurement tool’s ability to detect change in performance over time. The aim of the review was to summarise studies of responsiveness of lower limb physical performance measures dur...

    Authors: Katharine Scrivener, Catherine Sherrington and Karl Schurr

    Citation: BMC Neurology 2013 13:4

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  8. Content type: Research article

    Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out...

    Authors: Yu-Hao Zhou, Xiao-Fei Ye, Fei-Fei Yu, Xiao Zhang, Ying-Yi Qin, Jian Lu and Jia He

    Citation: BMC Neurology 2013 13:1

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  9. Content type: Study protocol

    Stroke is one of the major causes of loss of independence, decreased quality of life and mortality among elderly people. About half of the elderly stroke patients discharged after rehabilitation in a nursing h...

    Authors: Tom PMM Vluggen, Jolanda CM van Haastregt, Jeanine A Verbunt, Elly JM Keijsers and Jos MGA Schols

    Citation: BMC Neurology 2012 12:164

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  10. Content type: Research article

    Reduced upper extremity function is one of the most common impairments after stroke and has previously been reported in approximately 70-80% of patients in the acute stage. Acute care for stroke has changes ov...

    Authors: Hanna C Persson, Marina Parziali, Anna Danielsson and Katharina S Sunnerhagen

    Citation: BMC Neurology 2012 12:162

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  11. Content type: Research article

    Recombinant factor VIIa (rFVIIa) may be used for rapid hemostasis in life-threatening hemorrhage. In warfarin-associated intracerebral hemorrhage (wICH), FVIIa use is controversial and may carry significant th...

    Authors: Chou Sherry H-Y, Cai Xuemei, Konigsberg Rachael G, Bresette Linda M, Henderson Galen V, Sorond Farzaneh A and Feske Steven K

    Citation: BMC Neurology 2012 12:158

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  12. Content type: Research article

    As low and middle-income countries such as Vietnam experience the health transition from infectious to chronic diseases, the morbidity and mortality from stroke will rise. In line with the recommendation of th...

    Authors: David L Tirschwell, Thanh G N Ton, Kiet A Ly, Quang Van Ngo, Tung T Vo, Chien Hung Pham, William T Longstreth Jr and Annette L Fitzpatrick

    Citation: BMC Neurology 2012 12:150

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  13. Content type: Research article

    The purpose of this study was to examine associations between cardiovascular risk factors and cognitive ability in middle aged and elderly Lithuanian urban population.

    Authors: Abdonas Tamosiunas, Migle Baceviciene, Regina Reklaitiene, Ricardas Radisauskas, Kristina Jureniene, Adelina Azaraviciene, Dalia Luksiene, Vilija Malinauskiene, Evelina Daugeliene and Laura Sapranaviciute-Zabazlajeva

    Citation: BMC Neurology 2012 12:149

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  14. Content type: Study protocol

    Stroke represents one of the most costly and long-term disabling conditions in adulthood worldwide and there is a need to determine the effectiveness of rehabilitation programs in the late phase after stroke. ...

    Authors: Lina Bunketorp Käll, Åsa Lundgren-Nilsson, Christian Blomstrand, Marcela Pekna, Milos Pekny and Michael Nilsson

    Citation: BMC Neurology 2012 12:141

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  15. Content type: Research article

    Acute symptomatic hypoglycaemia is a differential diagnosis in patients presenting with stroke-like neurological impairment, but few textbooks describe the full brain imaging appearances. We systematically rev...

    Authors: Ai Wain Yong, Zoe Morris, Kirsten Shuler, Colin Smith and Joanna Wardlaw

    Citation: BMC Neurology 2012 12:139

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  16. Content type: Research article

    We tested the hypothesis that in patients with occlusion of the terminal internal carotid artery and/or the proximal middle cerebral artery, a diffusion abnormality of 70 ml or less is accompanied by a diffusi...

    Authors: Reza Hakimelahi, Albert J Yoo, Julian He, Lee H Schwamm, Michael H Lev, Pamela W Schaefer and Ramon Gilberto González

    Citation: BMC Neurology 2012 12:132

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  17. Content type: Study protocol

    Community ambulation is a highly complex skill requiring the ability to adapt to increased environmental complexity and perform multiple tasks simultaneously. After stroke, individuals demonstrate a diminished...

    Authors: Prudence Plummer-D’Amato, Anastasia Kyvelidou, Dagmar Sternad, Bijan Najafi, Raymond M Villalobos and David Zurakowski

    Citation: BMC Neurology 2012 12:129

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  18. Content type: Research article

    Pyrexia after stroke (temperature ≥37.5°C) is associated with poor prognosis, but information on timing of body temperature changes and relationship to stroke severity and subtypes varies.

    Authors: Bartosz Karaszewski, Ralph GR Thomas, Martin S Dennis and Joanna M Wardlaw

    Citation: BMC Neurology 2012 12:123

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  19. Content type: Study protocol

    Family function may have an influence on the mental health deterioration of the caregivers of dependent family members and it could have a varying importance on the care of dependents. Little attention has bee...

    Authors: Vicente Gil-Guillen, Concepcion Carratala-Munuera, Juan Carlos Andres Ortega, Domingo Orozco-Beltran, José Martínez Ribera, Avelino Pereira Expósito, Pablo Martínez Cánovas, Eduardo Payá Mora, Emilio Mayoral Azofra, Antonio Fernández Giménez, Adriana Lopez-Pineda, Patricia Lorca-Amorrich, Carlos Plaza-Sirvent, Elisabet Berzosa Sola, Ramon Salas-Rico and Angel Fernandez-Garcia

    Citation: BMC Neurology 2012 12:118

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  20. Content type: Research article

    Data about the risk factors of stroke are sparse in the Middle East populations. We aimed to determine the potential risk factors and their population attributable fraction (PAF) for stroke in an Iranian popul...

    Authors: Noushin Fahimfar, Davood Khalili, Reza Mohebi, Fereidoun Azizi and Farzad Hadaegh

    Citation: BMC Neurology 2012 12:117

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  21. Content type: Research article

    Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, s...

    Authors: Eufrozina Selariu, Elisabet Zia, Marco Brizzi and Kasim Abul-Kasim

    Citation: BMC Neurology 2012 12:109

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  22. Content type: Research article

    Patients in neurologic in-patient rehabilitation are at risk of cardio- and cerebrovascular events. Microalbuminuria (MAU) is frequent and an important risk predictor but has not been validated in in-patient r...

    Authors: Dirk Sander, Christian Weimar, Peter Bramlage, Tobias Brandt, Ludger Rosin and Mario Siebler

    Citation: BMC Neurology 2012 12:102

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  23. Content type: Research article

    Neurogenic claudication (NC) is a common symptom in patients with lumbar spinal stenosis (LSS). The Neurogenic Claudication Outcome Score (NCOS) is a very short instrument for measuring functional status in th...

    Authors: Parisa Azimi, Hassan Reza Mohammadi and Ali Montazeri

    Citation: BMC Neurology 2012 12:101

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  24. Content type: Research article

    Central post-stroke pain (CPSP) is a neuropathic pain syndrome associated with somatosensory abnormalities due to central nervous system lesion following a cerebrovascular insult. Post-stroke pain (PSP) refers...

    Authors: Rogério Adas Ayres de Oliveira, Daniel Ciampi de Andrade, André Guelman Gomes Machado and Manoel Jacobsen Teixeira

    Citation: BMC Neurology 2012 12:89

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  25. Content type: Research article

    The correlation between intracranial pressure (ICP) and intraocular pressure (IOP) is still controversial in literature and hence whether IOP can be used as a non-invasive surrogate of ICP remains unknown. The...

    Authors: Zhen Li, Yingxin Yang, Yan Lu, Dachuan Liu, Erhe Xu, Jianping Jia, Diya Yang, Xiaojun Zhang, Huiqing Yang, Daqing Ma and Ningli Wang

    Citation: BMC Neurology 2012 12:66

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  26. Content type: Research article

    Since atherogenesis is related to oxidative stress, our objective was to study the association of oxidative stress markers with the vascular recurrence in non-cardioembolic stroke.

    Authors: David Brea, Jaume Roquer, Joaquín Serena, Tomás Segura and José Castillo

    Citation: BMC Neurology 2012 12:65

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  27. Content type: Research article

    Certain immune-mediated diseases (IMDs) have been associated with increased risk for cardiovascular disorders. The aim of the present study was to examine whether there is an association between 32 different I...

    Authors: Bengt Zöller, Xinjun Li, Jan Sundquist and Kristina Sundquist

    Citation: BMC Neurology 2012 12:41

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  28. Content type: Case report

    We report the case of a chronic stroke patient (62 months after injury) showing total absence of motor activity evoked by transcranial magnetic stimulation (TMS) of spared regions of the left motor cortex, but...

    Authors: Julià L Amengual, Antoni Valero-Cabré, Misericordia Veciana de las Heras, Nurja Rojo, Seán Froudist-Walsh, Pablo Ripollés, Nils Bodammer, Bahram Mohammadi, Jordi Montero, Carles Grau, Thomas F Münte and Antoni Rodríguez-Fornells

    Citation: BMC Neurology 2012 12:35

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  29. Content type: Research article

    Previous studies have reported white matter (WM) brain alterations in asymptomatic patients with human immunodeficiency virus (HIV).

    Authors: Bianca Stubbe-Drger, Michael Deppe, Siawoosh Mohammadi, Simon S Keller, Harald Kugel, Nora Gregor, Stefan Evers, Peter Young, E-Bernd Ringelstein, Gabriele Arendt, Stefan Knecht and Ingo W Husstedt

    Citation: BMC Neurology 2012 12:23

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  30. Content type: Case report

    The intracranial localization of large artery disease is recognized as the main cause of ischemic stroke in the world, considering all countries, although its global burden is widely underestimated. Indeed it ...

    Authors: Giovanni Malferrari, Marialuisa Zedde, Gianni De Berti, Massimo Maggi and Norina Marcello

    Citation: BMC Neurology 2011 11:154

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  31. Content type: Case report

    Infarcts of the corpus callosum are rare and have not been well documented previously. As for a variety of signs and symptoms presented, alien hand syndrome (AHS) can be easily overlooked.

    Authors: Jun Liang Yuan, Shuang Kun Wang, Xiao Juan Guo and Wen Li Hu

    Citation: BMC Neurology 2011 11:142

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  32. Content type: Research article

    This study aimed to investigate the long-term mortality and recurrence rate of stroke in first-time stroke patients with symptomatic isolated middle cerebral artery disease (MCAD) under medical management.

    Authors: Mi Sun Oh, Kyung-Ho Yu, Min-Kyung Chu, Hyeo-Il Ma, Yun Joong Kim, Joo Yong Kim and Byung-Chul Lee

    Citation: BMC Neurology 2011 11:138

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  33. Content type: Research article

    Robotic devices are expected to be widely used in various applications including support for the independent mobility of the elderly with muscle weakness and people with impaired motor function as well as supp...

    Authors: Shinichiro Maeshima, Aiko Osawa, Daisuke Nishio, Yoshitake Hirano, Koji Takeda, Hiroshi Kigawa and Yoshiyuki Sankai

    Citation: BMC Neurology 2011 11:116

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  34. Content type: Research article

    A possible synergic role of serum uric acid (SUA) with thrombolytic therapies is controversial and needs further investigations. We therefore evaluated association of admission SUA with clinical improvement an...

    Authors: Nicola Logallo, Halvor Naess, Titto T Idicula, Jan Brogger, Ulrike Waje-Andreassen and Lars Thomassen

    Citation: BMC Neurology 2011 11:114

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  35. Content type: Research article

    stroke is the main cause of disability in high-income countries, and ranks second as a cause of death worldwide. Patients with acute stroke are at risk for infections, but reported post-stroke infection rates v....

    Authors: Willeke F Westendorp, Paul J Nederkoorn, Jan-Dirk Vermeij, Marcel G Dijkgraaf and Diederik van de Beek

    Citation: BMC Neurology 2011 11:110

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  36. Content type: Research article

    Atrial fibrillation (AF) is a leading cause of fatal ischemic stroke. It was recently reported that international normalized ratio (INR) levels were associated with infarct volumes. However, factors other than...

    Authors: Semi Oh, Suk Jae Kim, Soo-Kyoung Ryu, Gyeong-Moon Kim, Chin Sang Chung, Kwang Ho Lee and Oh Young Bang

    Citation: BMC Neurology 2011 11:107

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  37. Content type: Case report

    Paradoxical embolism due to pulmonary arteriovenous malformations is the main mechanism of brain infarction in patients with hereditary hemorrhagic telangiectasia. International Guidelines have recently been p...

    Authors: Espartaco Ribeiro, Julien Cogez, Emmanuel Babin, Fausto Viader and Gilles Defer

    Citation: BMC Neurology 2011 11:84

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  38. Content type: Research article

    Previous studies suggest central nervous system involvement in chronic fatigue syndrome (CFS), yet there are no established diagnostic criteria. CFS may be difficult to differentiate from clinical depression. ...

    Authors: Frank H Duffy, Gloria B McAnulty, Michelle C McCreary, George J Cuchural and Anthony L Komaroff

    Citation: BMC Neurology 2011 11:82

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  39. Content type: Research article

    Decompressive hemicraniectomy is a life-saving procedure for patients with malignant middle cerebral artery infarctions. However, the neuropsychological sequelae in such patients have up to now received little...

    Authors: Holger Schmidt, Trutz Heinemann, Judith Elster, Marija Djukic, Stefan Harscher, Katja Neubieser, Hilmar Prange, Andreas Kastrup and Veit Rohde

    Citation: BMC Neurology 2011 11:77

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  40. Content type: Research article

    Spontaneous intracerebral hemorrhage (ICH) is a devastating form of stroke with the high mortality twofold to sixfold higher than that for ischemic stroke. But the treatment of haematomas within the basal gang...

    Authors: Houguang Zhou, Yu Zhang, Ling Liu, Xu Han, Yinghong Tao, Yuping Tang, Wei Hua, Jianzhong Xue and Qiang Dong

    Citation: BMC Neurology 2011 11:76

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  41. Content type: Research article

    Angiopoietin-1 (Ang-1) and -2 (Ang-2) are keyplayers in the regulation of endothelial homeostasis and vascular proliferation. Angiopoietins may play an important role in the pathophysiology of cerebral vasospa...

    Authors: Marlene Fischer, Gregor Broessner, Anelia Dietmann, Ronny Beer, Raimund Helbok, Bettina Pfausler, Andreas Chemelli, Erich Schmutzhard and Peter Lackner

    Citation: BMC Neurology 2011 11:59

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  42. Content type: Research article

    Thrombolysis is a dynamic and time-dependent process influenced by the haemodynamic conditions. Currently there is no model that allows for time-continuous, non-contact measurements under physiological flow co...

    Authors: Florian C Roessler, Marcus Ohlrich, Jan H Marxsen, Marc Schmieger, Peter-Karl Weber, Florian Stellmacher, Peter Trillenberg, Jürgen Eggers and Günter Seidel

    Citation: BMC Neurology 2011 11:58

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  43. Content type: Research article

    Traditional magnetic resonance (MR) imaging can identify abnormal changes in ipsilateral thalamus in patients with unilateral middle cerebral artery (MCA) infarcts. However, it is difficult to demonstrate thes...

    Authors: Chuo Li, Xueying Ling, Sirun Liu, Anding Xu, Yusheng Zhang, Shihui Xing, Zhong Pei and Jinsheng Zeng

    Citation: BMC Neurology 2011 11:49

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  44. Content type: Research article

    Guidelines recommend maintaining the heart rate (HR) of acute stroke patients within physiological limits; data on the frequency and predictors of significant deviations from these limits are scarce.

    Authors: Martin A Ritter, Anne Rohde, Peter U Heuschmann, Rainer Dziewas, Jörg Stypmann, Darius G Nabavi and Bernd E Ringelstein

    Citation: BMC Neurology 2011 11:47

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