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BMC Neurology

Child neurology

Section edited by Dimitrios Zafeiriou

This section is dedicated to all aspects of pediatric neurology. Topics of interest include, but are not limited to, pediatric neuroradiology including MRI, fetal MRI, autism, epilepsy and beta thalassemia.

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  1. Content type: Case report

    Mutations in proteins involved in the glycosylphosphatidylinositol anchor biosynthesis and remodeling pathway are associated with autosomal recessive forms of intellectual disability. Recently mutations in the PG...

    Authors: Matthias Kettwig, Orly Elpeleg, Eike Wegener, Steffi Dreha-Kulaczewski, Marco Henneke, Jutta Gärtner and Peter Huppke

    Citation: BMC Neurology 2016 16:74

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  2. Content type: Research article

    Cerebral palsy (CP) is the main cause of severe physical impairment during childhood and has commonly shown oral motor association. It has been considered as the main cause of the high prevalence of problems i...

    Authors: Vanessa Vieira Pinto, Levy Anderson César Alves, Fausto M. Mendes and Ana Lídia Ciamponi

    Citation: BMC Neurology 2016 16:55

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  3. Content type: Case report

    Mutant rodent models have highlighted the importance of the ventricular ependymal cells and the subcommissural organ (a brain gland secreting glycoproteins into the cerebrospinal fluid) in the development of f...

    Authors: Eduardo Ortega, Rosa I. Muñoz, Nelly Luza, Francisco Guerra, Monserrat Guerra, Karin Vio, Roberto Henzi, Jaime Jaque, Sara Rodriguez, James P. McAllister and Esteban Rodriguez

    Citation: BMC Neurology 2016 16:45

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  4. Content type: Study protocol

    Previous studies have shown that the predictive control of movements is impaired in children with Developmental Coordination Disorder (DCD), most likely due to a deficit in the internal modeling of movements. ...

    Authors: Imke L. J. Adams, Bert Steenbergen, Jessica M. Lust and Bouwien C. M. Smits-Engelsman

    Citation: BMC Neurology 2016 16:5

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  5. Content type: Research article

    Home-based training is becoming ever more important with increasing demands on the public health systems. We investigated whether individualized and supervised interactive home-based training delivered through...

    Authors: Jakob Lorentzen, Line Z. Greve, Mette Kliim-Due, Betina Rasmussen, P. E. Bilde and Jens B. Nielsen

    Citation: BMC Neurology 2015 15:75

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  7. Content type: Research article

    Youth with spina bifida (SB) are less fit and active than other groups with childhood disability. While recent studies have shown benefits of exercise training, the increased fitness levels do not sustain or l...

    Authors: Manon AT Bloemen, Olaf Verschuren, Claudia van Mechelen, Hanneke E Borst, Arina J de Leeuw, Marsha van der Hoef and Janke F de Groot

    Citation: BMC Neurology 2015 15:11

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  8. Content type: Research article

    Minocycline, a member of the tetracycline family, has a low risk of adverse effects and an ability to improve behavioral performance in humans with cognitive disruption. We performed a single-arm open-label tr...

    Authors: Joseph C Grieco, Stephanie L Ciarlone, Maria Gieron-Korthals, Mike R Schoenberg, Amanda G Smith, Rex M Philpot, Helen S Heussler, Jessica L Banko and Edwin J Weeber

    Citation: BMC Neurology 2014 14:232

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  9. Content type: Research article

    Children with unilateral Cerebral Palsy (CP) often show diminished awareness of the remaining capacity of their affected upper limb. This phenomenon is known as Developmental Disregard (DD). DD has been explai...

    Authors: Ingar M Zielinski, Bert Steenbergen, C Marjolein Baas, Pauline BM Aarts and Marijtje LA Jongsma

    Citation: BMC Neurology 2014 14:221

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  10. Content type: Study protocol

    Cerebral palsy is the most common physical disability of childhood and early detection is possible using evidence based assessments. Systematic reviews indicate early intervention trials rarely demonstrate eff...

    Authors: Catherine Morgan, Iona Novak, Russell C Dale, Andrea Guzzetta and Nadia Badawi

    Citation: BMC Neurology 2014 14:203

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  11. Content type: Study protocol

    Cerebral palsy (CP) and brain injury (BI) are common conditions that have devastating effects on a child’s ability to use their hands. Hand splinting and task-specific training are two interventions that are o...

    Authors: Michelle Jackman, Iona Novak and Natasha Lannin

    Citation: BMC Neurology 2014 14:144

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  12. Content type: Research article

    Up to a third of children with Autism Spectrum Disorder (ASD) manifest regressive autism (R-ASD).They show normal early development followed by loss of language and social skills. Absent evidence-based therapi...

    Authors: Frank H Duffy, Aditi Shankardass, Gloria B McAnulty, Yaman Z Eksioglu, David Coulter, Alexander Rotenberg and Heidelise Als

    Citation: BMC Neurology 2014 14:70

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  13. Content type: Research article

    Assessment of arm-hand use is very important in children with cerebral palsy (CP) who encounter arm-hand problems. To determine validity and reliability of new instruments to assess actual performance, a set o...

    Authors: Ryanne JM Lemmens, Yvonne JM Janssen-Potten, Annick AA Timmermans, Anke Defesche, Rob JEM Smeets and Henk AM Seelen

    Citation: BMC Neurology 2014 14:52

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  14. Content type: Research article

    The contribution of cerebrovascular function to cognitive performance is gaining increased attention. Transcranial doppler (TCD) is portable, reliable, inexpensive and extremely well tolerated by young and cli...

    Authors: Mireille J Bakker, Jessica Hofmann, Owen F Churches, Nicholas A Badcock, Mark Kohler and Hannah AD Keage

    Citation: BMC Neurology 2014 14:43

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  15. Content type: Research article

    In a subset of children with unilateral Cerebral Palsy (CP) a discrepancy between capacity and performance of the affected upper limb can be observed. This discrepancy is known as Developmental Disregard (DD)....

    Authors: Ingar M Zielinski, Marijtje LA Jongsma, C Marjolein Baas, Pauline BM Aarts and Bert Steenbergen

    Citation: BMC Neurology 2014 14:6

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  16. Content type: Research article

    Learning Disorders (LD) are complex diseases that affect about 2-10% of the school-age population. We performed neuropsychological and psychopathological evaluation, in order to investigate comorbidity in chil...

    Authors: Lucia Margari, Maura Buttiglione, Francesco Craig, Arcangelo Cristella, Concetta de Giambattista, Emilia Matera, Francesca Operto and Marta Simone

    Citation: BMC Neurology 2013 13:198

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  17. Content type: Research article

    Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis (AFP) in the post-poliomyelitis eradication era. This is the first study done to identify the epidemiology, clinical features, ...

    Authors: Jagar Jasem, Kawa Marof, Adnan Nawar, Yosra Khalaf, Sirwan Aswad, Faisal Hamdani, Monirul Islam and Andre Kalil

    Citation: BMC Neurology 2013 13:195

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  18. Content type: Research article

    Mucopolysaccharidosis type III (MPS III) is an autosomal recessive disorder caused by deficiency of a specific enzyme leading to heparan sulfate (HS) accumulation within cells and to eventual progressive cereb...

    Authors: Svitlana Garbuzova-Davis, Santhia Mirtyl, Sebastian A Sallot, Diana G Hernandez-Ontiveros, Edward Haller and Paul R Sanberg

    Citation: BMC Neurology 2013 13:174

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  19. Content type: Research article

    The Observational Skills Assessment Score (OSAS) measures amount and quality of use of the affected hand in children with unilateral Cerebral Palsy (CP) in bimanual activities and could therefore be a valuable...

    Authors: Lucianne Speth, Yvonne Janssen-Potten, Pieter Leffers, Eugene Rameckers, Anke Defesche, Richard Geers, Rob Smeets and Hans Vles

    Citation: BMC Neurology 2013 13:152

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  20. Content type: Study protocol

    Children with congenital hemiplegia often present with limitations in using their impaired upper limb which impacts on independence in activities of daily living, societal participation and quality of life. Tr...

    Authors: Roslyn N Boyd, Jenny Ziviani, Leanne Sakzewski, Laura Miller, Joanne Bowden, Ross Cunnington, Robert Ware, Andrea Guzzetta, Richard AL Macdonell, Graeme D Jackson, David F Abbott and Stephen Rose

    Citation: BMC Neurology 2013 13:68

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