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BMC Neurology


Section edited by Marwan Sabbagh

This section focuses on neurodegeneration. Topics of interest include, but are not limited to, Alzheimer’s disease, Parkinson’s Disease, frontotemporal dementias, Lewy body dementia, vascular dementia, mild cognitive impairment and basic aspects of neurodegenerative diseases and prion diseases.

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  1. Content type: Research article

    Dementia has been associated with an increased risk of hip fracture. However, little research has been conducted on the impact of dementia on wrist or vertebral fracture development. The aim of this study was ...

    Authors: Hao-Kuang Wang, Chao-Ming Hung, Sheng-Hsiang Lin, Yi-Cheng Tai, Kang Lu, Po-Chou Liliang, Chi-Wei Lin, Yi-Che Lee, Pei-Hsuan Fang, Li-Ching Chang and Ying-Chun Li

    Citation: BMC Neurology 2014 14:175

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  2. Content type: Case report

    Creutzfeldt-Jakob disease and Hashimoto's encephalopathy often show similar clinical presentation. Among Creutzfeldt-Jakob disease mimics, Hashimoto's encephalopathy is particularly important as it is treatabl...

    Authors: Jae-Won Jang, So Young Park, Young Ho Park, Jung E Kim and SangYun Kim

    Citation: BMC Neurology 2014 14:179

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  3. Content type: Research article

    The objectives of this study were to explore the relationship between olfactory impairment, cognitive measures, and brain structure volumes in healthy elderly individuals, compared to patients with amnestic mi...

    Authors: Grete Kjelvik, Ingvild Saltvedt, Linda R White, Pål Stenumgård, Olav Sletvold, Knut Engedal, Kristina Skåtun, Ann Kristin Lyngvær, Hill Aina Steffenach and Asta K Håberg

    Citation: BMC Neurology 2014 14:168

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  4. Content type: Research article

    The Kii peninsula of Japan is one of the foci of amyotrophic lateral sclerosis and parkinsonism-dementia complex (ALS/PDC) in the world. The purpose of this study is to clarify the neuropsychological features ...

    Authors: Akihiro Shindo, Yukito Ueda, Shigeki Kuzuhara and Yasumasa Kokubo

    Citation: BMC Neurology 2014 14:151

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  5. Content type: Case report

    The diagnosis of dementia with Lewy bodies (DLB) is often challenging in elderly individuals, not only for its various clinical features, sometimes, but also for its rare changes of periodic synchronous discha...

    Authors: Li Sun, Jie Cao, Feng na Chu, Zan Wang and Yudan Lv

    Citation: BMC Neurology 2014 14:112

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  6. Content type: Research article

    Intervention and treatment in Alzheimer’s disease dementia (AD-dementia) can be cost effective but the majority of patients are not diagnosed in a timely manner. Technology is now available that can enable the...

    Authors: Jennifer H Barnett, Lily Lewis, Andrew D Blackwell and Matthew Taylor

    Citation: BMC Neurology 2014 14:101

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  7. Content type: Research article

    Cholinesterase inhibitors (ChEIs) such as donepezil have the effect of delaying progression of Alzheimer’s disease (AD), but their effect on life expectancy is unclear. We analyzed the influence of donepezil o...

    Authors: Kenichi Meguro, Mari Kasai, Kyoko Akanuma, Mitsue Meguro, Hiroshi Ishii and Satoshi Yamaguchi

    Citation: BMC Neurology 2014 14:83

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  8. Content type: Research article

    Biomarkers based on the underlying pathology of Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have the potential to improve diagnosis and understanding of the substrate for cognitive impairment ...

    Authors: Andrew Siderowf, Michael J Pontecorvo, Holly A Shill, Mark A Mintun, Anupa Arora, Abhinay D Joshi, Ming Lu, Charles H Adler, Douglas Galasko, Carolyn Liebsack, Daniel M Skovronsky and Marwan N Sabbagh

    Citation: BMC Neurology 2014 14:79

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  9. Content type: Study protocol

    The aging of the population has led to the increase of chronic diseases, especially dementia and cardiovascular diseases, and it has become necessary for their relatives to dedicate more time in caregiving.

    Authors: Emiliano Rodriguez-Sánchez, José María Criado-Gutiérrez, Sara Mora-Simón, M Paz Muriel-Diaz, Manuel A Gómez-Marcos, José I Recio-Rodríguez, M Carmen Patino-Alonso, Luis F Valero-Juan, José A Maderuelo-Fernandez and Luis García-Ortiz

    Citation: BMC Neurology 2014 14:63

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  10. Content type: Research article

    We investigated levels of the β-amyloid 1–42 (Aβ42), total tau protein (T-tau) and tau phosphorylated at position threonine 181 (P-tau) in cerebrospinal fluid (CSF) of idiopathic normal pressure hydrocephalus ...

    Authors: Tae Sung Lim, Jun Young Choi, Sun Ah Park, Young Chul Youn, Hyun Young Lee, Byung Gon Kim, In Soo Joo, Kyoon Huh and So Young Moon

    Citation: BMC Neurology 2014 14:66

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  11. Content type: Research article

    The Insulin-like Growth Factor (IGF)-related system is implicated in neuroregeneration and cell repair, as well as regulating lifespan. IGF-II, one component of this system, has also been found to affect memor...

    Authors: Joakim Hertze, Katarina Nägga, Lennart Minthon and Oskar Hansson

    Citation: BMC Neurology 2014 14:64

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  12. Content type: Research article

    Gait ability and cognitive function are interrelated during both normal walking (NW) and dual-task walking (DTW), and gait ability is thus adversely affected by cognitive impairment in both situations. However...

    Authors: Takehiko Doi, Hiroyuki Shimada, Hyuma Makizako, Kota Tsutsumimoto, Kazuki Uemura, Yuya Anan and Takao Suzuki

    Citation: BMC Neurology 2014 14:67

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  13. Content type: Research article

    England has one of the highest rates of hospital death in dementia in Europe. How this has changed over time is unknown. This study aimed to analyse temporal trends in place of death in dementia over a recent ...

    Authors: Katherine E Sleeman, Yuen K Ho, Julia Verne, Wei Gao and Irene J Higginson

    Citation: BMC Neurology 2014 14:59

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  14. Content type: Research article

    TTP488, an antagonist at the Receptor for Advanced Glycation End products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer’s disease (AD). A previous report describes decrea...

    Authors: Aaron H Burstein, Imogene Grimes, Douglas R Galasko, Paul S Aisen, Marwan Sabbagh and Adnan MM Mjalli

    Citation: BMC Neurology 2014 14:12

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  15. Content type: Study protocol

    A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and cond...

    Authors: Perminder S Sachdev, Darren M Lipnicki, Nicole A Kochan, John D Crawford, Kenneth Rockwood, Shifu Xiao, Juan Li, Xia Li, Carol Brayne, Fiona E Matthews, Blossom CM Stephan, Richard B Lipton, Mindy J Katz, Karen Ritchie, Isabelle Carrière, Marie-Laure Ancelin…

    Citation: BMC Neurology 2013 13:165

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  16. Content type: Case report

    Due to the nature of neurodegenerative disorders, patients with primary progressive aphasia develop cognitive impairment other than aphasia as the disorder progresses. The progression of logopenic variant prim...

    Authors: Michitaka Funayama, Yoshitaka Nakagawa, Yoko Yamaya, Fumihiro Yoshino, Masaru Mimura and Motoichiro Kato

    Citation: BMC Neurology 2013 13:158

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