Movement disorders

Section edited by Yih-Ru Wu

This section covers all types and aspects of movement disorders. Topics of include, but are not limited to, Parkinson's Disease, transcranial magnetic stimulation, spasticity, dyskinesia, movement disorders, rehabilitation and spinal cord injury.

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  1. Technical advance

    A computerized tablet system for evaluating treatment of essential tremor by magnetic resonance guided focused ultrasound

    Transcranial magnetic resonance guided focused ultrasound is an emerging technology under evaluation for treatment of essential tremor, a prevalent movement disorder. A qualitative evaluation is performed by a...

    Fred Tam, Yuexi Huang, Michael L. Schwartz, Tom A. Schweizer, Kullervo Hynynen and Simon J. Graham

    BMC Neurology 2017 17:74

    Published on: 17 April 2017

  2. Research article

    Short-term motor learning through non-immersive virtual reality task in individuals with down syndrome

    Down syndrome (DS) has unique physical, motor and cognitive characteristics. Despite cognitive and motor difficulties, there is a possibility of intervention based on the knowledge of motor learning. However, ...

    Carlos Bandeira de Mello Monteiro, Talita Dias da Silva, Luiz Carlos de Abreu, Felipe Fregni, Luciano Vieira de Araujo, Fernando Henrique Inocêncio Borba Ferreira and Claudio Leone

    BMC Neurology 2017 17:71

    Published on: 14 April 2017

  3. Study protocol

    Assessment and rehabilitation of central sensory impairments for balance in mTBI using auditory biofeedback: a randomized clinical trial

    Complaints of imbalance are common non-resolving signs in individuals with post-concussive syndrome. Yet, there is no consensus rehabilitation for non-resolving balance complaints following mild traumatic brai...

    Peter C. Fino, Robert J. Peterka, Timothy E. Hullar, Chad Murchison, Fay B. Horak, James C. Chesnutt and Laurie A. King

    BMC Neurology 2017 17:41

    Published on: 23 February 2017

  4. Study protocol

    Evaluation and implementation of highly challenging balance training in clinical practice for people with Parkinson’s disease: protocol for the HiBalance effectiveness-implementation trial

    If people with progressive neurological diseases are to avail of evidence-based rehabilitation, programs found effective in randomized controlled trials (RCT’s) must firstly be adapted and tested in clinical e...

    Breiffni Leavy, Lydia Kwak, Maria Hagströmer and Erika Franzén

    BMC Neurology 2017 17:27

    Published on: 7 February 2017

  5. Research article

    Monitoring training activity during gait-related balance exercise in individuals with Parkinson’s disease: a proof-of-concept-study

    Despite the benefits of balance exercise in clinical populations, balance training programs tend to be poorly described, which in turn makes it difficult to evaluate important training components and compare b...

    David Conradsson, Håkan Nero, Niklas Löfgren, Maria Hagströmer and Erika Franzén

    BMC Neurology 2017 17:19

    Published on: 31 January 2017

  6. Study protocol

    Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial

    Cerebellar ataxia (CA) is a frequent and often disabling condition that impairs motor functioning and impacts on quality of life (QoL). No medication has yet been proven effective for the symptomatic or even c...

    Katharina Feil, Christine Adrion, Julian Teufel, Sylvia Bösch, Jens Claassen, Ilaria Giordano, Holger Hengel, Heike Jacobi, Thomas Klockgether, Thomas Klopstock, Wolfgang Nachbauer, Ludger Schöls, Claudia Stendel, Ellen Uslar, Bart van de Warrenburg, Ingrid Berger…

    BMC Neurology 2017 17:7

    Published on: 10 January 2017

  7. Research article

    Looking beyond the brain to improve the pathogenic understanding of Parkinson’s disease: implications of whole transcriptome profiling of Patients’ skin

    Parkinson’s Disease is a progressive neurodegenerative disease, characterized by symptoms of motor impairment, resulting from the loss of dopaminergic neurons in the midbrain, however non-neuronal symptoms are...

    Anu Planken, Lille Kurvits, Ene Reimann, Liis Kadastik-Eerme, Külli Kingo, Sulev Kõks and Pille Taba

    BMC Neurology 2017 17:6

    Published on: 10 January 2017

  8. Research article

    Guidelines for dementia or Parkinson’s disease with depression or anxiety: a systematic review

    Depression and anxiety remain under-diagnosed and under-treated in those with neurologic diseases such as dementia or Parkinson’s Disease (PD). Our objectives were to first, to provide a synthesis of high qual...

    Zahra Goodarzi, Bria Mele, Selynne Guo, Heather Hanson, Nathalie Jette, Scott Patten, Tamara Pringsheim and Jayna Holroyd-Leduc

    BMC Neurology 2016 16:244

    Published on: 25 November 2016

  9. Research article

    A step toward essential tremor gene discovery: identification of extreme phenotype and screening of HTRA2 and ANO3

    Essential tremor (ET) is characterized by a frequent family history. No monogenic form of ET has been identified. We aimed at exploring ET patients to identify distinct subgroups and facilitate the identificat...

    Mathilde Renaud, Christophe Marcel, Gabrielle Rudolf, Mickaël Schaeffer, Ouhaïd Lagha-Boukbiza, Jean-Baptiste Chanson, Jamel Chelly, Mathieu Anheim and Christine Tranchant

    BMC Neurology 2016 16:238

    Published on: 23 November 2016

  10. Case report

    Asphyxia due to laryngeal spasm as a severe complication of awake deep brain stimulation for Parkinson’s disease: a case report

    In accordance with German neurosurgical and neurological consensus recommendations, lead placements for deep brain stimulation (DBS) in patients with Parkinson’s disease (PD) are usually performed with the pat...

    Kajetan L. von Eckardstein, Friederike Sixel-Döring, Stephan Kazmaier, Claudia Trenkwalder, Jason M. Hoover and Veit Rohde

    BMC Neurology 2016 16:216

    Published on: 8 November 2016

  11. Study protocol

    The Parkin’Play study: protocol of a phase II randomized controlled trial to assess the effects of a health game on cognition in Parkinson’s disease

    In Parkinson’s disease (PD), cognitive impairment is an important non-motor symptom heralding the development of dementia. Effective treatments to slow down the rate of cognitive decline in PD patients with mi...

    Sjors C. F. van de Weijer, Annelien A. Duits, Bastiaan R. Bloem, Roy P. Kessels, Jacobus F. A. Jansen, Sebastian Köhler, Gerrit Tissingh and Mark L. Kuijf

    BMC Neurology 2016 16:209

    Published on: 3 November 2016

  12. Research article

    The effects of a mindfulness-based lifestyle program for adults with Parkinson’s disease: a mixed methods, wait list controlled randomised control study

    Parkinson’s disease (PD) is the second commonest neurodegenerative disease in developed countries. Current treatment for PD is pharmacologically focused and can have significant side-effects. There is increasi...

    Jenny Advocat, Joanne Enticott, Brooke Vandenberg, Craig Hassed, Jennifer Hester and Grant Russell

    BMC Neurology 2016 16:166

    Published on: 8 September 2016

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