Erratum to: COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015), a global –clinical evaluations, serum biomarkers, genetic studies and neuroimaging– prospective, multicenter, non-interventional, long-term study on Parkinson’s disease progression

Authors: Diego Santos-García, Pablo Mir, Esther Cubo, Lydia Vela, Mari Cruz Rodríguez-Oroz, Maria José Martí, José Matías Arbelo, Jon Infante, Jaime Kulisevsky and Pablo Martínez-Martín

Behavioural interventions for people living with adult-onset primary dystonia: a systematic review

Primary dystonia is a chronic neurological movement disorder that causes abnormal muscle movements. Pain and emotional distress may accompany these physical symptoms. Behavioural interventions are used to help...

Authors: C. J. Bernstein, D. R. Ellard, G. Davies, E. Hertenstein, N. K. Y. Tang, M. Underwood and H. Sandhu

COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015), a global –clinical evaluations, serum biomarkers, genetic studies and neuroimaging– prospective, multicenter, non-interventional, long-term study on Parkinson’s disease progression

Parkinson’s disease (PD) is a progressive neurodegenerative disorder causing motor and non-motor symptoms that can affect independence, social adjustment and the quality of life (QoL) of both patients and care...

Authors: Diego Santos-García, Pablo Mir, Esther Cubo, Lydia Vela, Mari Cruz Rodríguez-Oroz, Maria José Martí, José Matías Arbelo, Jon Infante, Jaime Kulisevsky and Pablo Martínez-Martín

Reliability of timed walking tests and temporo-spatial gait parameters in youths with neurological gait disorders

The 10-Meter Walk Tests (10MWT) and the 6-Minute Walk Test (6MinWT) are applied to assess gait capacity in paediatric patients. To better objectify changes in qualitative aspects of gait, temporo-spatial param...

Authors: Judith V. Graser, Claudia Letsch and Hubertus J. A. van Hedel

Effects on mobility training and de-adaptations in subjects with Spinal Cord Injury due to a Wearable Robot: a preliminary report

Spinal cord injury (SCI) is a severe neurological disorder associated not only with ongoing medical complications but also with a significant loss of mobility and participation. The introduction of robotic tec...

Authors: Patrizio Sale, Emanuele Francesco Russo, Michele Russo, Stefano Masiero, Francesco Piccione, Rocco Salvatore Calabrò and Serena Filoni

Meaning of self-management from the perspective of individuals with traumatic spinal cord injury, their caregivers, and acute care and rehabilitation managers: an opportunity for improved care delivery

The trend of decreasing length of stay in rehabilitation facilities has led to individuals with spinal cord injury (SCI) entering the community with unmet needs and fewer self-care skills to prevent secondary ...

Authors: Sarah E. P. Munce, Fiona Webster, Michael G. Fehlings, Sharon E. Straus, Eunice Jang and Susan B. Jaglal

Effect of augmenting cholinergic function on gait and balance

Impaired mobility and falls are clinically important complications of Parkinson’s disease (PD) and a major detractor from quality of life for which there are limited therapies. Pathological, neuroimaging and c...

Authors: Martina Mancini, Brett W. Fling, Anne Gendreau, Jodi Lapidus, Fay B. Horak, Kathy Chung and John G. Nutt

Case report of optic atrophy in Dentatorubropallidoluysian Atrophy (DRPLA)

Dentatorubropallidoluysian atrophy (DRPLA) is a rare autosomal dominant neurodegenerative disease that is associated with numerous movement disorders. Ocular problems also occur with DRPLA with reports of corn...

Authors: Michael R. Silver, Kapil D. Sethi, Shyamal H. Mehta, Fenwick T. Nichols and John C. Morgan

Observational cohort study of the natural history of Niemann-Pick disease type C in the UK: a 5-year update from the UK clinical database

Niemann-Pick disease type C (NP-C) is a rare neurovisceral lipid storage disorder characterised by progressive, disabling neurological symptoms and premature death in most patients. During the last decade, nat...

Authors: Jackie Imrie, Lesley Heptinstall, Stephen Knight and Kate Strong

Study protocol of “CHAPS”: a randomized controlled trial protocol of Care Coordination for Health Promotion and Activities in Parkinson’s Disease to improve the quality of care for individuals with Parkinson’s disease

Parkinson’s disease, the second most common neurodegenerative disease, is diagnostically defined by motor impairments, but also includes often under-recognized impairments in cognition, mood, sleep, and the au...

Authors: Karen Connor, Eric Cheng, Hilary C. Siebens, Martin L. Lee, Brian S. Mittman, David A. Ganz and Barbara Vickrey

Exploring factors related to physical activity in cervical dystonia

People with disabilities have reported worse health status than people without disabilities and receiving fewer preventive health services such as counseling around exercise habits. This is noteworthy consider...

Authors: Lena Zetterberg, Charlotte Urell and Elisabeth Anens

Protocol of a randomised delayed-start double-blind placebo-controlled multi-centre trial for Levodopa in EArly Parkinson’s disease: the LEAP-study

The aim of this study is to investigate if early treatment with levodopa has a beneficial disease modifying effect on Parkinson’s disease (PD) symptoms and functional health, improves the ability to (maintain)...

Authors: Constant V. M. Verschuur, S. R. Suwijn, B. Post, M. Dijkgraaf, B. R. Bloem, J. J. van Hilten, T. van Laar, G. Tissingh, G. Deuschl, A. E. Lang, R. J. de Haan and R. M. A. de Bie

Argentine tango in Parkinson disease – a systematic review and meta-analysis

Parkinson’s Disease (PD) is a neurodegenerative disease with increasing motor and non-motor symptoms in advanced stages. In addition to conventional exercise therapy and drug treatment, Argentine Tango (AT) is...

Authors: Désirée Lötzke, Thomas Ostermann and Arndt Büssing

Association between vestibulo-ocular reflex suppression, balance, gait, and fall risk in ageing and neurodegenerative disease: protocol of a one-year prospective follow-up study

Falls frequency increases with age and particularly in neurogeriatric cohorts. The interplay between eye movements and locomotion may contribute substantially to the occurrence of falls, but is hardly investig...

Authors: Karin Srulijes, David J. Mack, Jochen Klenk, Lars Schwickert, Espen A. F. Ihlen, Michael Schwenk, Ulrich Lindemann, Miriam Meyer, Srijana K.C., Markus A. Hobert, Kathrin Brockmann, Isabel Wurster, Jörn K. Pomper, Matthis Synofzik, Erich Schneider, Uwe Ilg…

A multi-centre, randomised controlled trial of the effectiveness of PDSAFE to prevent falls among people with Parkinson’s: study protocol

Falls amongst people with Parkinson’s (PwP) result in significant disability and reduced quality of life. There is emerging evidence that exercise-based and physiotherapeutic interventions are of benefit for i...

Authors: Victoria A Goodwin, Ruth Pickering, Claire Ballinger, Helen Roberts, Emma McIntosh, Sarah Lamb, Alice Nieuwboer, Lynn Rochester and Ann Ashburn

Accuracy and cutoff values of delayed heart to mediastinum ratio with ¹²³I-metaiodobenzylguanidine cardiac scintigraphy for Lewy body disease diagnoses

Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson’s disease (PD) and Lewy body dementia (LBD)). However, delayed heart/medias...

Authors: Guillaume Lamotte, Rémy Morello, Adrien Lebasnier, Denis Agostini and Gilles L. Defer

Ceruloplasmin activity and iron chelation treatment of patients with Parkinson’s disease

Growing body of evidence suggests that Parkinson’s disease (PD) is associated with oxidative damage via iron accumulation in the substantia nigra (SN). Low ceruloplasmin (CP)-ferroxidase activity has been iden...

Authors: Guillaume Grolez, Caroline Moreau, Bernard Sablonnière, Guillaume Garçon, Jean-Christophe Devedjian, Sayah Meguig, Patrick Gelé, Christine Delmaire, Regis Bordet, Luc Defebvre, Ioav Z Cabantchik and David Devos

The cyclical lower extremity exercise for Parkinson’s trial (CYCLE): methodology for a randomized controlled trial

Motor and non-motor impairments affect quality of life in individuals with Parkinson’s disease. Our preliminary research indicates that forced exercise cycling, a mode of exercise in which a participant’s volu...

Authors: Anson B Rosenfeldt, Matthew Rasanow, Amanda L Penko, Erik B Beall and Jay L Alberts

Design of the Park-in-Shape study: a phase II double blind randomized controlled trial evaluating the effects of exercise on motor and non-motor symptoms in Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder with a wide range of motor and non-motor symptoms. Despite optimal medical management, PD still results in a high disability rate and secondary complica...

Authors: Nicolien M van der Kolk, Sebastiaan Overeem, Nienke M de Vries, Roy PC Kessels, Rogier Donders, Marc Brouwer, Daniela Berg, Bart Post and Bas R Bloem

Retraction Note: Gene expression profiling analysis of the putamen for the investigation of compensatory mechanisms in Parkinson’s disease

Authors: Lianbo Gao, Honghua Gao, Huan Zhou and Yanyuan Xu