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BMC Neurology

Movement disorders

Section edited by Yih-Ru Wu

This section covers all types and aspects of movement disorders. Topics of include, but are not limited to, Parkinson's Disease, transcranial magnetic stimulation, spasticity, dyskinesia, movement disorders, rehabilitation and spinal cord injury.

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  1. Content type: Study protocol

    Impaired mobility and falls are clinically important complications of Parkinson’s disease (PD) and a major detractor from quality of life for which there are limited therapies. Pathological, neuroimaging and c...

    Authors: Martina Mancini, Brett W. Fling, Anne Gendreau, Jodi Lapidus, Fay B. Horak, Kathy Chung and John G. Nutt

    Citation: BMC Neurology 2015 15:264

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  2. Content type: Case report

    Dentatorubropallidoluysian atrophy (DRPLA) is a rare autosomal dominant neurodegenerative disease that is associated with numerous movement disorders. Ocular problems also occur with DRPLA with reports of corn...

    Authors: Michael R. Silver, Kapil D. Sethi, Shyamal H. Mehta, Fenwick T. Nichols and John C. Morgan

    Citation: BMC Neurology 2015 15:260

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  3. Content type: Research article

    Niemann-Pick disease type C (NP-C) is a rare neurovisceral lipid storage disorder characterised by progressive, disabling neurological symptoms and premature death in most patients. During the last decade, nat...

    Authors: Jackie Imrie, Lesley Heptinstall, Stephen Knight and Kate Strong

    Citation: BMC Neurology 2015 15:257

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  4. Content type: Study protocol

    Parkinson’s disease, the second most common neurodegenerative disease, is diagnostically defined by motor impairments, but also includes often under-recognized impairments in cognition, mood, sleep, and the au...

    Authors: Karen Connor, Eric Cheng, Hilary C. Siebens, Martin L. Lee, Brian S. Mittman, David A. Ganz and Barbara Vickrey

    Citation: BMC Neurology 2015 15:258

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  5. Content type: Research article

    People with disabilities have reported worse health status than people without disabilities and receiving fewer preventive health services such as counseling around exercise habits. This is noteworthy consider...

    Authors: Lena Zetterberg, Charlotte Urell and Elisabeth Anens

    Citation: BMC Neurology 2015 15:247

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  6. Content type: Study protocol

    The aim of this study is to investigate if early treatment with levodopa has a beneficial disease modifying effect on Parkinson’s disease (PD) symptoms and functional health, improves the ability to (maintain)...

    Authors: Constant V. M. Verschuur, S. R. Suwijn, B. Post, M. Dijkgraaf, B. R. Bloem, J. J. van Hilten, T. van Laar, G. Tissingh, G. Deuschl, A. E. Lang, R. J. de Haan and R. M. A. de Bie

    Citation: BMC Neurology 2015 15:236

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  7. Content type: Study protocol

    Falls frequency increases with age and particularly in neurogeriatric cohorts. The interplay between eye movements and locomotion may contribute substantially to the occurrence of falls, but is hardly investig...

    Authors: Karin Srulijes, David J. Mack, Jochen Klenk, Lars Schwickert, Espen A. F. Ihlen, Michael Schwenk, Ulrich Lindemann, Miriam Meyer, Srijana K.C., Markus A. Hobert, Kathrin Brockmann, Isabel Wurster, Jörn K. Pomper, Matthis Synofzik, Erich Schneider, Uwe Ilg…

    Citation: BMC Neurology 2015 15:192

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  8. Content type: Study protocol

    Falls amongst people with Parkinson’s (PwP) result in significant disability and reduced quality of life. There is emerging evidence that exercise-based and physiotherapeutic interventions are of benefit for i...

    Authors: Victoria A Goodwin, Ruth Pickering, Claire Ballinger, Helen Roberts, Emma McIntosh, Sarah Lamb, Alice Nieuwboer, Lynn Rochester and Ann Ashburn

    Citation: BMC Neurology 2015 15:81

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  9. Content type: Research article

    Different studies have found diminished cardiac metaiodobenzylguanidine (MIBG) uptake in Lewy body (LB) related conditions (Parkinson’s disease (PD) and Lewy body dementia (LBD)). However, delayed heart/medias...

    Authors: Guillaume Lamotte, Rémy Morello, Adrien Lebasnier, Denis Agostini and Gilles L. Defer

    Citation: BMC Neurology 2015 15:83

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  10. Content type: Research article

    Growing body of evidence suggests that Parkinson’s disease (PD) is associated with oxidative damage via iron accumulation in the substantia nigra (SN). Low ceruloplasmin (CP)-ferroxidase activity has been iden...

    Authors: Guillaume Grolez, Caroline Moreau, Bernard Sablonnière, Guillaume Garçon, Jean-Christophe Devedjian, Sayah Meguig, Patrick Gelé, Christine Delmaire, Regis Bordet, Luc Defebvre, Ioav Z Cabantchik and David Devos

    Citation: BMC Neurology 2015 15:74

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  11. Content type: Study protocol

    Motor and non-motor impairments affect quality of life in individuals with Parkinson’s disease. Our preliminary research indicates that forced exercise cycling, a mode of exercise in which a participant’s volu...

    Authors: Anson B Rosenfeldt, Matthew Rasanow, Amanda L Penko, Erik B Beall and Jay L Alberts

    Citation: BMC Neurology 2015 15:63

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  12. Content type: Study protocol

    Parkinson’s disease (PD) is a neurodegenerative disorder with a wide range of motor and non-motor symptoms. Despite optimal medical management, PD still results in a high disability rate and secondary complica...

    Authors: Nicolien M van der Kolk, Sebastiaan Overeem, Nienke M de Vries, Roy PC Kessels, Rogier Donders, Marc Brouwer, Daniela Berg, Bart Post and Bas R Bloem

    Citation: BMC Neurology 2015 15:56

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  13. Content type: Case report

    We peformed a ventral intermediate nucleus (Vim) thalamotomy in a patient with Holmes’ tremor and palatal tremor. The frequencies of these movement disorders were 4 Hz and 3 Hz, respectively. Vim thalamotomy s...

    Authors: Futaba Maki, Sumito Sato, Katsushige Watanabe, Toshiyuki Yanagisawa, Yuta Hagiwara, Takahiro Shimizu and Yasuhiro Hasegawa

    Citation: BMC Neurology 2015 15:26

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  14. Content type: Research article

    Achieving optimal symptom control with minimal side effects is a major goal in clinical practice. Dual-agent dopamine receptor agonist (DA) therapy in Parkinson’s disease (PD) may represent a promising approac...

    Authors: Jong-Min Kim, Sun Ju Chung, Jae Woo Kim, Beom Seok Jeon, Pritibha Singh, Stephan Thierfelder, Junji Ikeda and Lars Bauer

    Citation: BMC Neurology 2015 15:17

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  15. Content type: Research article

    Uric acid has antioxidant effects on neurons. Abnormally high levels of uric acid are, however, associated with gout. Previous studies have suggested that high levels of uric acid (and the presence of gout) ma...

    Authors: Julia Pakpoor, Olena O Seminog, Sreeram V Ramagopalan and Michael J Goldacre

    Citation: BMC Neurology 2015 15:16

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  16. Content type: Study protocol

    Effective treatment of locomotor dysfunction in Parkinson disease (PD) is essential, as gait difficulty is an early and major contributor to disability. Exercise is recommended as an adjunct to traditional tre...

    Authors: Gammon M Earhart, Ryan P Duncan, John L Huang, Joel S Perlmutter and Kristen A Pickett

    Citation: BMC Neurology 2015 15:9

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