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Movement disorders

This section covers all types and aspects of movement disorders. Topics of include, but are not limited to, Parkinson's Disease, transcranial magnetic stimulation, spasticity, dyskinesia, movement disorders, rehabilitation and spinal cord injury.

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  1. Psychoses such as hallucinations are a frequent non-motor problem in patients with Parkinson disease (PD) and serious psychosis requires anti-psychotic medications that worsen Parkinsonism. Although psychosis ...

    Authors: Hideyuki Sawada, Tomoko Oeda, Kenji Yamamoto, Atsushi Umemura, Satoshi Tomita, Ryutaro Hayashi, Masayuki Kohsaka and Takashi Kawamura

    Citation: BMC Neurology 2013 13:145

    Content type: Research article

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  2. With an increased life expectancy for the general population as well as for those ageing with chronic diseases, there are major challenges to the affected individuals and their families, but also to health car...

    Authors: Maria H Nilsson and Susanne Iwarsson

    Citation: BMC Neurology 2013 13:142

    Content type: Study protocol

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  3. Locomotor training using robots is increasingly being used for rehabilitation to reduce manpower and the heavy burden on therapists, and the effectiveness of such techniques has been investigated. The robot su...

    Authors: Hiroaki Kawamoto, Kiyotaka Kamibayashi, Yoshio Nakata, Kanako Yamawaki, Ryohei Ariyasu, Yoshiyuki Sankai, Masataka Sakane, Kiyoshi Eguchi and Naoyuki Ochiai

    Citation: BMC Neurology 2013 13:141

    Content type: Research article

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  4. Several reports have described that individual periodic leg movements during sleep (PLMS) activities are associated with autonomic nervous system activity occurring shortly before each PLMS activity. Neverthel...

    Authors: Taeko Sasai, Masato Matsuura and Yuichi Inoue

    Citation: BMC Neurology 2013 13:139

    Content type: Research article

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  5. Patients with Parkinson’s disease often suffer from reduced mobility due to impaired postural control. Balance exercises form an integral part of rehabilitative therapy but the effectiveness of existing interv...

    Authors: Maarten RC van den Heuvel, Erwin EH van Wegen, Cees JT de Goede, Ingrid AL Burgers-Bots, Peter J Beek, Andreas Daffertshofer and Gert Kwakkel

    Citation: BMC Neurology 2013 13:137

    Content type: Study protocol

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  6. Wilson’s disease (WD) is a genetic disorder which can be controlled fairly well with decupuration therapy. However, symptoms, on rare occasions, can worsen even when WD is being treated. Herein, we report a ca...

    Authors: Young Eun Kim, Ji Young Yun, Hui-Jun Yang, Han-Joon Kim and Beom S Jeon

    Citation: BMC Neurology 2013 13:127

    Content type: Case report

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  7. OnabotulinumtoxinA has demonstrated significant benefit in adult focal spasticity. This study reviews the injection patterns (i.e., muscle distribution, dosing) of onabotulinumtoxinA for treatment of adult spa...

    Authors: Luba Nalysnyk, Spyridon Papapetropoulos, Philip Rotella, Jason C Simeone, Katharine E Alter and Alberto Esquenazi

    Citation: BMC Neurology 2013 13:118

    Content type: Research article

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  8. Only a few case reports and case series dealing with oral and dental health care are available in literature until now. The aim of the present pilot study was to determine the status of dental health in compar...

    Authors: Carsten Saft, Jürgen E Andrich, Thomas Müller, Julia Becker and Jochen Jackowski

    Citation: BMC Neurology 2013 13:114

    Content type: Research article

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  9. Ropinirole prolonged release (RPR) is a once-daily formulation. However, there may be individual pharmacokinetic differences so that multiple dosing may be preferred in some individuals. This study compares on...

    Authors: Ji Young Yun, Han-Joon Kim, Jee-Young Lee, Young Eun Kim, Ji Seon Kim, Jong-Min Kim and Beom S Jeon

    Citation: BMC Neurology 2013 13:113

    Content type: Research article

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  11. Cervical dystonia is characterized by involuntary muscle contractions of the neck and abnormal head positions that affect daily life activities and social life of patients. Patients are usually treated with bo...

    Authors: Joost van den Dool, Bart Visser, J Hans TM Koelman, Raoul HH Engelbert and Marina AJ Tijssen

    Citation: BMC Neurology 2013 13:85

    Content type: Study protocol

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  12. Weight loss is a frequent feature in the motor neuron disease Amyotrophic lateral sclerosis (ALS). In this study we investigated possible causes of weight loss in ALS, its impact on mood/quality of life (QOL) ...

    Authors: Sonja Körner, Melanie Hendricks, Katja Kollewe, Antonia Zapf, Reinhard Dengler, Vincenzo Silani and Susanne Petri

    Citation: BMC Neurology 2013 13:84

    Content type: Research article

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  14. Posterior reversible encephalopathy syndrome (PRES) is a transient clinical and neuroradiologic syndrome caused by cerebral vasogenic edema. Various reversible neurologic symptoms were shown in patients with P...

    Authors: Asuka Nakajima, Yuji Ueno, Hideki Shimura, Taiki Kambe, Kenya Nishioka, Nobutaka Hattori and Takao Urabe

    Citation: BMC Neurology 2013 13:79

    Content type: Case report

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  15. To compare the value of ultrasonography for diagnosing carpal tunnel syndrome (CTS) in patients with and without diabetes mellitus (DM).

    Authors: Nai-Wen Tsai, Lian-Hui Lee, Chi-Ren Huang, Wen-Neng Chang, Hung-Chen Wang, Yu-Jun Lin, Wei-Che Lin, Tsu-Kung Lin, Ben-Chung Cheng, Yu-Jih Su, Chia-Te Kung, Shu-Fang Chen and Cheng-Hsien Lu

    Citation: BMC Neurology 2013 13:65

    Content type: Research article

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  16. We report a case of childhood onset, generalized dystonia due to slowly progressive bilateral striatal necrosis associated with anti-N-methyl-D-aspartate receptor (NMDAR) antibodies. This clinical phenotype ha...

    Authors: Charalampos Tzoulis, Christian Vedeler, Mette Haugen, Anette Storstein, Gia Tuong Tran, Ivar Otto Gjerde, Martin Biermann, Thomas Schwarzlmüller and Laurence A Bindoff

    Citation: BMC Neurology 2013 13:55

    Content type: Case report

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  17. Over the last years, the introduction of robotic technologies into Parkinson’s disease rehabilitation settings has progressed from concept to reality. However, the benefit of robotic training remains elusive. ...

    Authors: Patrizio Sale, Maria Francesca De Pandis, Domenica Le Pera, Ivan Sova, Veronica Cimolin, Andrea Ancillao, Giorgio Albertini, Manuela Galli, Fabrizio Stocchi and Marco Franceschini

    Citation: BMC Neurology 2013 13:50

    Content type: Research article

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  18. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) was first described in 2010 by Pittock and colleagues. All reported patients presented with diplopia and...

    Authors: Juerd Wijntjes, Ernest J Wouda, Carl EH Siegert, Giorgos B Karas and Annemarie MM Vlaar

    Citation: BMC Neurology 2013 13:49

    Content type: Case report

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  19. Traditionally, tinnitus accompanied by hemifacial spasm has been considered a type of hyperactive neurovascular compression syndrome that is similar to hemifacial spasm alone because of the anatomically close ...

    Authors: Won Seok Chang, Bong Soo Kim, Ji Eun Lee, Hyun Ho Jung, Kiwoong Kim, Hyuk Chan Kwon, Yong Ho Lee and Jin Woo Chang

    Citation: BMC Neurology 2013 13:42

    Content type: Research article

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  20. Eukaryotic translation initiation factor 4-gamma 1 (EIF4G1) gene mutations have recently been reported in autosomal dominant, late-onset Parkinson’s disease (LOPD). We carried out genetic analysis to determine th...

    Authors: Kai Li, Bei-sha Tang, Ji-feng Guo, Ming-xing Lou, Zhan-yun Lv, Zhen-hua Liu, Yun Tian, Cheng-yuan Song, Kun Xia and Xin-xiang Yan

    Citation: BMC Neurology 2013 13:38

    Content type: Research article

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  21. Using surrogate biomarkers for disease progression as endpoints in neuroprotective clinical trials may help differentiate symptomatic effects of potential neuroprotective agents from true disease-modifying eff...

    Authors: David JM McGhee, Pamela L Royle, Paul A Thompson, David E Wright, John P Zajicek and Carl E Counsell

    Citation: BMC Neurology 2013 13:35

    Content type: Research article

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  23. There have been several reports concerning the survival time after symptom onset in patients with amyotrophic lateral sclerosis (ALS). However, little is known about how the choice of physician (i.e., general ...

    Authors: Osamu Kano, Konosuke Iwamoto, Hirono Ito, Yuji Kawase, Derek Cridebring, Ken Ikeda and Yasuo Iwasaki

    Citation: BMC Neurology 2013 13:19

    Content type: Research article

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  24. Increasing evidence provides a clear association between rapid eye movement sleep behavior disorders (RBD) and Parkinson’s disease (PD), but the clinical features that determine the co-morbidity of RBD and PD ...

    Authors: Keisuke Suzuki, Tomoyuki Miyamoto, Masayuki Miyamoto, Yuka Watanabe, Shiho Suzuki, Muneto Tatsumoto, Masaoki Iwanami, Tsubasa Sada, Taro Kadowaki, Ayaka Numao, Kenichi Hashimoto, Hideki Sakuta and Koichi Hirata

    Citation: BMC Neurology 2013 13:18

    Content type: Research article

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  25. Recent work has demonstrated that fall risk can be attributed to cognitive as well as motor deficits. Indeed, everyday walking in complex environments utilizes executive function, dual tasking, planning and sc...

    Authors: Anat Mirelman, Lynn Rochester, Miriam Reelick, Freek Nieuwhof, Elisa Pelosin, Giovanni Abbruzzese, Kim Dockx, Alice Nieuwboer and Jeffrey M Hausdorff

    Citation: BMC Neurology 2013 13:15

    Content type: Study protocol

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  26. To explore current status and choices regarding diagnosis and treatment of Parkinson’s disease (PD) among physicians, general neurologists and movement disorders specialists in China via a national survey.

    Authors: Wei Chen, Shuai Chen, Qin Xiao, Gang Wang and Sheng-Di Chen

    Citation: BMC Neurology 2012 12:155

    Content type: Research article

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  27. Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of unknown etiology, manifesting as combination of parkinsonism, cerebellar syndrome and dysautonomia. Disease-modifying therapies are ...

    Authors: Peter Novak, Arlene Williams, Paula Ravin, Omar Zurkiya, Amir Abduljalil and Vera Novak

    Citation: BMC Neurology 2012 12:131

    Content type: Research article

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  29. There is increasing scientific knowledge about the interaction between physiological (musculoskeletal, neuromuscular, cognitive and sensory) systems and their influence on balance and walking impairments in Pa...

    Authors: David Conradsson, Niklas Löfgren, Agneta Ståhle, Maria Hagströmer and Erika Franzén

    Citation: BMC Neurology 2012 12:111

    Content type: Study protocol

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  30. Essential tremor (ET) is one of the commonest movement disorders though the prevalence varies globally. There is paucity of data on ET prevalence in sub-Saharan Africa. The study aimed to determine the prevale...

    Authors: Njideka U Okubadejo, Idowu A Bankole, Oluwadamilola O Ojo, Frank I Ojini and Mustapha A Danesi

    Citation: BMC Neurology 2012 12:110

    Content type: Research article

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  31. Lymphocyte-depleted Hodgkin’s lymphoma is the rarest form of classical Hodgkin’s lymphoma, accounting for < 1% of all cases. Patients often have advanced-stage disease at the time of presentation with an aggre...

    Authors: Ekkehard M Kasper, Fred C Lam, Markus M Luedi, Pascal O Zinn and German A Pihan

    Citation: BMC Neurology 2012 12:64

    Content type: Case report

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  32. Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle...

    Authors: Akihiko Hoshi, Teiji Yamamoto, Saeko Kikuchi, Tomoko Soeda, Keiko Shimizu and Yoshikazu Ugawa

    Citation: BMC Neurology 2012 12:22

    Content type: Case report

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  34. Progressive supranuclear palsy (PSP) and parkinsonian variant of multiple system atrophy (MSA-P) are clinically difficult to differentiate from idiopathic Parkinson's disease (PD), particularly in the early st...

    Authors: Masahiko Suzuki, Masaya Hashimoto, Masayuki Yoshioka, Maiko Murakami, Keiichi Kawasaki and Mitsuyoshi Urashima

    Citation: BMC Neurology 2011 11:157

    Content type: Research article

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  35. Children diagnosed with spastic Cerebral Palsy (CP) often show perceptual and cognitive problems, which may contribute to their functional deficit. Here we investigated if altered ability to determine whether ...

    Authors: Anina Ritterband-Rosenbaum, Mark S Christensen, Mette Kliim-Due, Line Z Petersen, Betina Rasmussen and Jens B Nielsen

    Citation: BMC Neurology 2011 11:150

    Content type: Research article

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  36. Pure akinesia (PA) is a distinct form of parkinsonism characterized by freezing phenomena. Little is known about brain tumor-associated PA. We highlight the clinicoradiological changes in a patient with PA and...

    Authors: Susumu Ishihara, Osamu Kano, Ken Ikeda, Reiko Shimokawa, Kiyokazu Kawabe and Yasuo Iwasaki

    Citation: BMC Neurology 2011 11:137

    Content type: Case report

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  37. Low doses of dopamine agonists (DA) and levodopa are effective in the treatment of restless legs syndrome (RLS). A range of impulse control and compulsive behaviours (ICBs) have been reported following the use...

    Authors: Valerie Voon, Andrea Schoerling, Sascha Wenzel, Vindhya Ekanayake, Julia Reiff, Claudia Trenkwalder and Friederike Sixel-Döring

    Citation: BMC Neurology 2011 11:117

    Content type: Research article

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  39. Early initiation of pharmacotherapy in Parkinson's disease (PD) is nowadays widely advocated by experts since the delay of treatment has shown to be associated with a significant deterioration of health relate...

    Authors: Matthias Löhle and Heinz Reichmann

    Citation: BMC Neurology 2011 11:112

    Content type: Debate

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  40. A recent trial involving predominantly Caucasian subjects with Parkinson Disease (PD) showed switching overnight from an oral dopaminergic agonist to the rotigotine patch was well tolerated without loss of eff...

    Authors: Han-Joon Kim, Beom S Jeon, Won Yong Lee, Myoung Chong Lee, Jae Woo Kim, Jong-Min Kim, Tae-Beom Ahn, Jinwhan Cho, Sun Ju Chung, Frank Grieger, John Whitesides and Babak Boroojerdi

    Citation: BMC Neurology 2011 11:100

    Content type: Research article

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  41. Studies in animals suggest that the noradrenergic system arising from the locus coeruleus (LC) and dopaminergic pathways mutually influence each other. Little is known however, about the functional state of th...

    Authors: Ioannis U Isaias, Giorgio Marotta, Gianni Pezzoli, Osama Sabri, Johannes Schwarz, Paolo Crenna, Joseph Classen and Paolo Cavallari

    Citation: BMC Neurology 2011 11:88

    Content type: Research article

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  42. The evidence for associations between occupational factors and the risk of Parkinson's disease (PD) is inconsistent. We assessed the risk of PD associated with various occupational factors in Japan.

    Authors: Keiko Tanaka, Yoshihiro Miyake, Wakaba Fukushima, Satoshi Sasaki, Chikako Kiyohara, Yoshio Tsuboi, Tatsuo Yamada, Tomoko Oeda, Takami Miki, Nobutoshi Kawamura, Nobutaka Sakae, Hidenao Fukuyama, Yoshio Hirota and Masaki Nagai

    Citation: BMC Neurology 2011 11:83

    Content type: Case control study

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  43. Neuroregeneration is a relatively recent concept that includes neurogenesis, neuroplasticity, and neurorestoration - implantation of viable cells as a therapeutical approach.

    Authors: Ana M Enciu, Mihnea I Nicolescu, Catalin G Manole, Dafin F Mureşanu, Laurenţiu M Popescu and Bogdan O Popescu

    Citation: BMC Neurology 2011 11:75

    Content type: Debate

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  45. Although the soleus (Sol), medial gastrocnemius (MG), and lateral gastrocnemius (LG) muscles differ in function, composition, and innervations, it is a common practice is to investigate them as single H-reflex...

    Authors: Hesham N Alrowayeh, Mohamed A Sabbahi and Bruce Etnyre

    Citation: BMC Neurology 2011 11:65

    Content type: Research article

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  46. Chronic Fatigue Syndrome (CFS) came to attention in the 1980s, but initial investigations did not find organic causes. Now decades later, the etiology of CFS has yet to be understood, and the role of genetic p...

    Authors: Frederick Albright, Kathleen Light, Alan Light, Lucinda Bateman and Lisa A Cannon-Albright

    Citation: BMC Neurology 2011 11:62

    Content type: Research article

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  48. Frontotemporal lobar degeneration with ubiquitin and TDP-43 positive neuronal inclusions represents a novel entity (FTLD-TDP) that may be associated with motor neuron disease (FTLD-MND); involvement of extrapy...

    Authors: Robert Rusina, Gabor G Kovacs, Jindřich Fiala, Jakub Hort, Petr Ridzoň, Iva Holmerová, Thomas Ströbel and Radoslav Matěj

    Citation: BMC Neurology 2011 11:50

    Content type: Case report

    Published on:

  49. Because of the subjective nature of Restless Legs Syndrome (RLS) symptoms and the impact of these symptoms on sleep, patient-reported outcomes (PROs) play a prominent role as study endpoints in clinical trials...

    Authors: Daniel M Canafax, Abhijeet Bhanegaonkar, Murtuza Bharmal and Michael Calloway

    Citation: BMC Neurology 2011 11:48

    Content type: Research article

    Published on:

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