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  1. Spinal muscular atrophy (SMA) is a progressive degenerative neuromuscular disease. Nusinersen, with its quick onset of action, can benefit patients early in the treatment course. However, there are currently n...

    Authors: Hua Yang, Qiuji Tao, Dan Li, Jie Yang, Qianyun Cai, Jing Gan, Shaoping Huang and Rong Luo
    Citation: BMC Neurology 2023 23:35
  2. Creutzfeldt-Jakob disease (CJD) is a fatal and irreversible neurodegenerative disease. Identification of inexpensive and easy-to-implement biomarkers of CJD which could predict disease severity and patient sur...

    Authors: Yu Kong, Zhongyun Chen, Jing Zhang and Liyong Wu
    Citation: BMC Neurology 2023 23:34
  3. The carriers of damaging heterozygous variants in interferon regulatory factor 2 binding protein-like (IRF2BPL), encoding a member of the IRF2BP family of transcriptional regulators, may be affected by a varie...

    Authors: Fei Yang, Hui Li, Yi Dai, Ran Zhang and Jiang-tao Zhang
    Citation: BMC Neurology 2023 23:32
  4. Volumetric accuracy of using computed tomography perfusion (CTP) to estimate the post-treatment infarct in stroke patients with successful recanalization after mechanical thrombectomy (MT) has been studied a l...

    Authors: Xiao-Quan Xu, Gao Ma, Guang-Chen Shen, Shan-Shan Lu, Hai-Bin Shi, Ya-Xi Zhang, Yu Zhang, Fei-Yun Wu and Sheng Liu
    Citation: BMC Neurology 2023 23:31
  5. Investigations on the risk factors for the prognosis of cerebral venous sinus thrombosis (CVST) are limited. This study aimed to explore whether specific inflammatory factors and coagulation indictors are asso...

    Authors: Rui Sun, Feihong Huang, Wen Wu, Ge Yin, Qichao Ding, Zhengsheng Gu, Cunxiu Fan, Chenrui Song, Meng Liang, Xiaobei Liu and Xiaoying Bi
    Citation: BMC Neurology 2023 23:30
  6. Mild acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) may benefit from thrombolysis or thrombectomy therapy. However, the predictors for LVO in mild AIS patients have not been extensively...

    Authors: Zhengzhao Lu, Yunyun Xiong, Kaixuan Yang, Hongqiu Gu, Chunmiao Duan, Xingquan Zhao, Xia Meng and Yongjun Wang
    Citation: BMC Neurology 2023 23:29
  7. Patients with complex febrile seizures (CFS) often display abnormal laboratory results, unexpectedly prolonged seizures, and/or altered consciousness after admission. However, no standardized values have been ...

    Authors: Tsukasa Tanaka, Hiroshi Yamaguchi, Yusuke Ishida, Kazumi Tomioka, Masahiro Nishiyama, Daisaku Toyoshima, Azusa Maruyama, Hiroki Takeda, Hiroshi Kurosawa, Ryojiro Tanaka, Kandai Nozu and Hiroaki Nagase
    Citation: BMC Neurology 2023 23:28
  8. Early hematoma expansion (HE) occurs in 20 to 40% of spontaneous intracerebral hemorrhage (ICH) patients and is a primary determinant of early deterioration and poor prognosis. Previous studies have shown that...

    Authors: Yujian Li, Xiang Yang, Huiqing Zhou, Xuhui Hui, Hao Li and Jun Zheng
    Citation: BMC Neurology 2023 23:27
  9. Autonomic dysfunction is prevalent in ischemic stroke patients and associated with a worse clinical outcome. We aimed to evaluate autonomic dysfunction over time and the tolerability of the head-up tilt table ...

    Authors: Mathias Damkjær, Sofie Amalie Simonsen, Adam Vittrup Heiberg, Jesper Mehlsen, Anders Sode West, Poul Jennum and Helle Klingenberg Iversen
    Citation: BMC Neurology 2023 23:26
  10. Tolosa-Hunt syndrome (THS) is characterized by painful ophthalmoplegia caused by idiopathic granulomatous inflammation involving the cavernous sinus region. Patients respond well to steroid therapy. THS is inc...

    Authors: Wei He, Yinglin Zhu, Yinan Zhang, Liang Dong, Zefang Zhou and Jiying Zhou
    Citation: BMC Neurology 2023 23:25
  11. Autonomic dysfunctions including bladder dysfunction, gastrointestinal dysfunction and orthostasis are common symptoms of autoimmune glial fibrillary acidic protein astrocytopathy (A-GFAP-A); however, cardiac ...

    Authors: Pu-yuan Wen, Guang-qiang Wang, Lian-wei Dou, Qi Chen, Xian-wen Chen and Li Gong
    Citation: BMC Neurology 2023 23:24
  12. Intracranial aneurysms are the most common vascular cause of painful ophthalmoplegia. Symptoms include retro-orbital pain, diplopia, ophthalmoplegia, trigeminal neuropathy, or a combination of these. Most sing...

    Authors: Wanwan Zhang, Yinyin Xie, Jiwei Zhang, Cui Wang, Yajun Lian, Hongbo Liu and Nanchang Xie
    Citation: BMC Neurology 2023 23:23
  13. The association between intracranial artery calcification (IAC) and the risk of ischemic stroke occurrence or poor prognosis had not yet been fully understood. In this study, we conducted a meta-analysis of ex...

    Authors: Xuelong Li, Heng Du, Jia Li and Xiangyan Chen
    Citation: BMC Neurology 2023 23:21
  14. NEUROG1 gene is yet to be associated with a set of human phenotypes in the OMIM database. Three cases have previously been diagnosed with cranial dysinnervation due to biallelic variants in the NEUROG1 gene. This...

    Authors: Frenny Sheth, Jhanvi Shah, Ketan Patel, Darshan Patel, Deepika Jain, Jayesh Sheth and Harsh Sheth
    Citation: BMC Neurology 2023 23:20
  15. Do-not-attempt-resuscitation (DNAR) decisions for patients with infratentorial or large supratentorial intracerebral hemorrhages (ICHs) pose clinical and ethical challenges. We aimed to investigate factors ass...

    Authors: Amanda Soomägi, Adam Viktorisson and Katharina S. Sunnerhagen
    Citation: BMC Neurology 2023 23:19
  16. Measurement of the optic nerve sheath diameter (ONSD) provides a rapid, safe, and easy method for detecting increased intracranial pressure (ICP). However, the normal mean and upper limit values may vary accor...

    Authors: Guillermo Trocha, Andrés Bonilla, Camilo Romero, Jonathan Palacios and Nicolas Molano-Gonzalez
    Citation: BMC Neurology 2023 23:16
  17. Parkinson’s disease (PD) is a neurodegenerative disease and is clinically characterized by a series of motor symptoms (MS) and nonmotor symptoms (NMS). NMS often appear before MS, while cognitive impairment mo...

    Authors: Zhiguang Chen, Wei Zhang, Wen He, Yang Guang, Tengfei Yu, Yue Du and Rui Li
    Citation: BMC Neurology 2023 23:15
  18. Low frequency repetitive transcranial magnetic stimulation (rTMS) is commonly used to inhibit pathological hyperactivity of the auditory cortex in tinnitus. Novel and supposedly superior and faster inhibitory ...

    Authors: Stefan Schoisswohl, Berthold Langguth, Franziska C. Weber, Mohamed A. Abdelnaim, Tobias Hebel and Martin Schecklmann
    Citation: BMC Neurology 2023 23:14
  19. Carotid vulnerable plaque is an important risk factor for stroke occurrence and recurrence. However, the relationship between risk parameters related to carotid vulnerable plaque (plaque size, echogenicity, in...

    Authors: Linggang Cheng, Shuai Zheng, Jinghan Zhang, Fumin Wang, Xinyao Liu, Lin Zhang, Zhiguang Chen, Ye Cheng, Wei Zhang, Yi Li and Wen He
    Citation: BMC Neurology 2023 23:13
  20. Granulomatous hypophysitis is a rare disease that presents with chronic inflammation of the pituitary gland. In this study, we reported a case of granulomatous hypophysitis associated with a pituitary abscess.

    Authors: Mohammad Mahdi Rabiei, Kaveh Ebrahimzadeh, Zahra Davoudi, Farahnaz Bidari Zerehpoosh, Farid Javandoust Gharehbagh, Roghayeh Sedaghati, Legha Lotfollahi, Fatemeh Kalhor and Ilad Alavi Darazam
    Citation: BMC Neurology 2023 23:11
  21. We investigated the influence of the coronavirus disease 2019 (COVID-19) pandemic on the number of patients with acute ischemic stroke who received intravenous thrombolytic therapy (ITT) in Dalian, China, in 2...

    Authors: Xin Pan, Shubei Ma, Xiaowen Sui, Lili Xie, Furong Li, Zhengping Cheng, Li Cui and Hongling Zhao
    Citation: BMC Neurology 2023 23:10
  22. Glioblastoma (GBM) infrequently recurs in the infratentorial region. Such Infratentorial recurrence (ITR) has some clinically unique characteristics, such as presenting unspecific symptoms and providing patien...

    Authors: Daisuke Kawauchi, Makoto Ohno, Mai Honda-Kitahara, Yasuji Miyakita, Masamichi Takahashi, Shunsuke Yanagisawa, Yukie Tamura, Miyu Kikuchi, Koichi Ichimura and Yoshitaka Narita
    Citation: BMC Neurology 2023 23:9
  23. The Chronic Headache Education and Self-Management Study (CHESS) multicentre randomised trial evaluated the impact a group education and self-management support intervention with a best usual care plus relaxat...

    Authors: David R. Ellard, Vivien P. Nichols, Frances E. Griffiths, Martin Underwood and Stephanie J. C. Taylor
    Citation: BMC Neurology 2023 23:8
  24. Cytokine levels have been measured in acute encephalopathy (AE) to determine its pathology or as a diagnostic biomarker to distinguish it from febrile seizures (FS); however, the dynamics of cytokine level cha...

    Authors: Kazumi Tomioka, Masahiro Nishiyama, Shoichi Tokumoto, Hiroshi Yamaguchi, Kazunori Aoki, Yusuke Seino, Daisaku Toyoshima, Hiroshi Kurosawa, Hiroko Tada, Hiroshi Sakuma, Kandai Nozu, Azusa Maruyama, Ryojiro Tanaka, Kazumoto Iijima and Hiroaki Nagase
    Citation: BMC Neurology 2023 23:7
  25. Intracerebral hemorrhage (ICH) is the second most common subtype of stroke, with high mortality and morbidity. At present, there are no effective 6-month prognostic markers, particularly for younger patients. ...

    Authors: Yuyan Yang, Shanshan Huang, Yuchao Jia, Guini Song, Xiaodong Ye, Kai Lu, Guo Li, Furong Wang and Suiqiang Zhu
    Citation: BMC Neurology 2023 23:6
  26. The treatment of vasospasms during endovascular stroke treatment (EST) with intra-arterial nimodipine (NM) is routinely performed. However, the efficacy of resolving iatrogenic vasospasms during the angiograph...

    Authors: Jessica Jesser, Arne Potreck, Dominik Vollherbst, Fatih Seker, Min Chen, Silvia Schönenberger, Thuy D. Do, Martin Bendszus, Markus A. Möhlenbruch and Charlotte S. Weyland
    Citation: BMC Neurology 2023 23:5
  27. The majority of postoperative complications of tonsillectomy are bleeding. However, massive cerebral infarction following haemostasis is a very rare and serious complication and has rarely been reported clinic...

    Authors: Jinghao Zhao, Yubo Lei, Na Hu, Lang Xia, Liyang Zeng, Yongheng Zhang and Wei Qin
    Citation: BMC Neurology 2023 23:4
  28. Mild cognitive impairment is an age-dependent pre-dementia state caused by varied reasons. Early detection of MCI helps handle dementia. Vascular factors are vital for the occurrence of MCI. This study investi...

    Authors: Xiuqi Chen, Yufan Luo, Shufan Zhang, Xiaoli Yang, Zhiyuan Dong, Yilin Wang and Danhong Wu
    Citation: BMC Neurology 2023 23:3
  29. Although of high individual and socioeconomic relevance, a reliable prediction model for the prognosis of juvenile stroke (18–55 years) is missing. Therefore, the study presented in this protocol aims to prosp...

    Authors: Sonja Schönecker, Verena Hoffmann, Fady Albashiti, Reinhard Thasler, Marlien Hagedorn, Marie-Luise Louiset, Anna Kopczak, Jennifer Rösler, Enayatullah Baki, Silke Wunderlich, Florian Kohlmayer, Klaus Kuhn, Martin Boeker, Johannes Tünnerhoff, Sven Poli, Ulf Ziemann…
    Citation: BMC Neurology 2023 23:2
  30. Troponin elevation is common in ischemic stroke (IS) patients. The pathomechanisms involved are incompletely understood and comprise coronary and non-coronary causes, e.g. autonomic dysfunction. We investigate...

    Authors: Felipe A. Montellano, Elisabeth J. Kluter, Viktoria Rücker, Kathrin Ungethüm, Daniel Mackenrodt, Silke Wiedmann, Tassilo Dege, Anika Quilitzsch, Caroline Morbach, Stefan Frantz, Stefan Störk, Karl Georg Haeusler, Christoph Kleinschnitz and Peter U. Heuschmann
    Citation: BMC Neurology 2022 22:511
  31. TMS is being used to aid in the diagnosis of central nervous system (CNS) illnesses. It is useful in planning rehabilitation programs and setting appropriate goals for patients. We used a parabolic coil with b...

    Authors: Pimthong Jitsakulchaidej, Pakorn Wivatvongvana and Kittipong Kitisak
    Citation: BMC Neurology 2022 22:510
  32. The Clock Drawing Test (CDT) is used as a quick-to-conduct test for the diagnosis of dementia and a screening tool for cognitive impairments in neurological disorders. However, the association between the patt...

    Authors: Raheleh Heyrani, Atiye Sarabi-Jamab, Jordan Grafman, Nesa Asadi, Sarvenaz Soltani, Fatemeh Sadat Mirfazeli, Mostafa Almasi-Dooghaei, Seyed Vahid Shariat, Amin Jahanbakhshi, Tara Khoeini and Mohammad Taghi Joghataei
    Citation: BMC Neurology 2022 22:509
  33. Opsoclonus-myoclonus syndrome (OMS) is a rare, immune-mediated neurological disorder. In adults, the pathogenesis can be idiopathic, post-infectious or paraneoplastic, the latter etiology belonging to the ever...

    Authors: Raphael Reinecke, Annemarie Reiländer, Alexander Seiler, Christine Koch and Martin Voss
    Citation: BMC Neurology 2022 22:507
  34. Community-based exercise is a continuation and complement to inpatient rehabilitation for Parkinson's disease and does not require a professional physical therapist or equipment. The effects, parameters, and f...

    Authors: Chun-Lan Yang, Jia-Peng Huang, Ting-Ting Wang, Ying-Chao Tan, Yin Chen, Zi-Qi Zhao, Chao-Hua Qu and Yun Qu
    Citation: BMC Neurology 2022 22:505
  35. Approximately 60% of patients with autoimmune encephalitis (AE) exhibit secondary acute symptomatic seizures and showed highly sensitive to immunotherapy. However, it is difficult for many patients to receive ...

    Authors: Xiangsong Shi, Weiwei Cai, Xiulin Zhang, Heyue Pan, Chengbing Huang, Shouyong Wang and Jianyang Xu
    Citation: BMC Neurology 2022 22:503
  36. Little is known about the self-perceived level of disability of stroke survivors in the community. We aimed to characterise Health-related quality of life (HRQoL) 1 year after stroke and investigate how sociod...

    Authors: Hey Jean Lee, Jung-Kook Song, Jiyoung Moon, Keonyeop Kim, Hyeung-Keun Park, Gil-Won Kang, Jun-Ho Shin, Jongsoo Kang, Byoung-Gwon Kim, Young-Hoon Lee, Hye Seon Jeong, Lee Heeyoung, Won Kyung Lee, Seongheon Kim and Young-Kwon Park
    Citation: BMC Neurology 2022 22:501
  37. Amyloid-β-related angiitis (ABRA) is a rare complication of cerebral amyloid angiopathy, characterized by amyloid-β deposition in the leptomeningeal and cortical vessels with associated angiodestructive granul...

    Authors: Zita Reisz, Claire Troakes, Laszlo K. Sztriha and Istvan Bodi
    Citation: BMC Neurology 2022 22:500
  38. Authors: Dominik Stelzle, Joyce Kaducu, Veronika Schmidt, Tamara M. Welte, Bernard J. Ngowi, William Matuja, Gabrielle Escheu, Peter Hauke, Vivien Richter, Emilio Ovuga, Bettina Pfausler, Erich Schmutzhard, Action Amos, Wendy Harrison, Luise Keller and Andrea S. Winkler
    Citation: BMC Neurology 2022 22:499

    The original article was published in BMC Neurology 2022 22:321

  39. The MRI features of Diffuse midline glioma, H3 K27-altered and glioma in the midline without H3 K27-altered were compared and analyzed, and the changes in the apparent diffusion coefficient (ADC) of the two gr...

    Authors: Ji-ping Zhao, Xue-jun Liu, Hao-zhi Lin, Chun-xiao Cui, Ying-jie Yue, Song Gao and Hong-zhang Xu
    Citation: BMC Neurology 2022 22:498
  40. The efficacy of recanalization treatment in patients with ischemic stroke due to large vessel occlusion (LVO) is highly time dependent. We aimed to investigate the effects of an optimization of prehospital and...

    Authors: Stefan Krebs, Julia Ferrari, Alice Schürer, Astrid Chiari, Christian Neumann, Wilfried Lang and Marek Sykora
    Citation: BMC Neurology 2022 22:497

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