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  1. Primary microcephaly is defined as reduced occipital-frontal circumference noticeable before 36 weeks of gestation. Large amount of insults might lead to microcephaly including infections, hypoxia and genetic ...

    Authors: Vincent Picher-Martel, Yvan Labrie, Serge Rivest, Baiba Lace and Nicolas Chrestian
    Citation: BMC Neurology 2020 20:58
  2. Migraine is one of the most common neurological disorders that leads to disabilities. However, the conventional drug therapy for migraine might be unsatisfactory at times. Therefore, this meta-analysis aimed t...

    Authors: Hong Deng, Gai-gai Li, Hao Nie, Yang-yang Feng, Guang-yu Guo, Wen-liang Guo and Zhou-ping Tang
    Citation: BMC Neurology 2020 20:57
  3. Craniopharyngiomas are defined by the WHO as “benign” tumours, but their location and surgical treatment may be associated with major complications, one being chemical meningitis. Although rare, especially in ...

    Authors: Magdalena Chrościńska-Krawczyk, Ewa Zienkiewicz, Arkadiusz Podkowiński and Maria Klatka
    Citation: BMC Neurology 2020 20:56
  4. Perineuriomas are rare benign peripheral nerve sheath tumours of perineurial cell origin and can be classified into intraneural and extraneural perineuriomas. They most commonly present a mononeuropathy of gra...

    Authors: Anne-Kathrin Uerschels, Christos Krogias, Andreas Junker, Ulrich Sure, Karsten H. Wrede and Oliver Gembruch
    Citation: BMC Neurology 2020 20:55
  5. Current guidelines limit thrombolytic treatment of stroke to those patients who present within 4.5 h to minimize the risk of hemorrhagic complications. Risk of hemorrhage increases with increasing blood-brain ...

    Authors: Jarrhett Butler, Parisa Heidari, Sarah Blayney, Emi Hitomi, Marie Luby and Richard Leigh
    Citation: BMC Neurology 2020 20:54
  6. Myotonic dystrophy type 1 (DM1) is the most common disease that can cause muscle weakness and atrophy among adults. Normal pressure hydrocephalus (NPH) is characterized by the triad of gait disturbance, cognit...

    Authors: Junyang Wang, Ming Liu, Wenjie Shang, Zhongqin Chen and Guoping Peng
    Citation: BMC Neurology 2020 20:53
  7. Information of Previous studies on the prevalence of MS, including our study conducted 12 years ago, used to shape global prevalence map of MS. According to those results, Iran placed in medium-prevalence MS r...

    Authors: Seyed Mohammad Baghbanian, Hamed Cheraghmakani, Reza HabibiSaravi, Arash Azar and Fariba Ghasemihamedani
    Citation: BMC Neurology 2020 20:52
  8. Nonconvulsive status epilepticus (NCSE) is a state of ongoing seizure activity without convulsions. The heterogeneous and subtle clinical features of NCSE make diagnosis and treatment challenging. Here, we rep...

    Authors: Yi Yang, Shunyuan Zhang, Jinfeng Duan, Xianwen Zhang and Yufeng Tang
    Citation: BMC Neurology 2020 20:51
  9. Parkinson’s disease (PD) is a devastating neurodegenerative disorder. Reduced balance is one of the cardinal symptoms of PD, predisposing people living with PD to experience difficulties with the execution of ...

    Authors: Sofie LaGrone, Conran Joseph, Hanna Johansson, Birgit Enberg and Erika Franzén
    Citation: BMC Neurology 2020 20:50
  10. In 2015, the first nationwide, multicenter Multiple Sclerosis (MS) registry was initiated in the Kingdom of Saudi Arabia (KSA) mainly with an objective to describe current epidemiology, disease patterns, and c...

    Authors: Mohammed AlJumah, R. Bunyan, H. Al Otaibi, G. Al Towaijri, A. Karim, Y. Al Malik, M. Kalakatawi, S. Alrajeh, M. Al Mejally, H. Algahtani, A. Almubarak, E. Cupler, S. Alawi, S. Qureshi, S. Nahrir, A. Almalki…
    Citation: BMC Neurology 2020 20:49
  11. The medical imaging to differentiate World Health Organization (WHO) grade II (ODG2) from III (ODG3) oligodendrogliomas still remains a challenge. We investigated whether combination of machine leaning with ra...

    Authors: Sha-Sha Zhao, Xiu-Long Feng, Yu-Chuan Hu, Yu Han, Qiang Tian, Ying-Zhi Sun, Jie Zhang, Xiang-Wei Ge, Si-Chao Cheng, Xiu-Li Li, Li Mao, Shu-Ning Shen, Lin-Feng Yan, Guang-Bin Cui and Wen Wang
    Citation: BMC Neurology 2020 20:48
  12. It is unclear whether non-high-density lipoprotein cholesterol (Non-HDL-C) is associated with haemorrhagic transformation (HT) after acute ischaemic stroke (AIS). We aimed to explore the association between No...

    Authors: Yanan Wang, Quhong Song, Yajun Cheng, Chenchen Wei, Chen Ye, Junfeng Liu, Bo Wu and Ming Liu
    Citation: BMC Neurology 2020 20:47
  13. Persistent post-concussive symptoms (PPCS) affect up to 30% of individuals following mild traumatic brain injury. PPCS frequently includes exercise intolerance. Sub-symptom threshold aerobic exercise has been ...

    Authors: Leah J. Mercier, Tak S. Fung, Ashley D. Harris, Sean P. Dukelow and Chantel T. Debert
    Citation: BMC Neurology 2020 20:46
  14. Chulalongkorn Stroke Center is a comprehensive stroke center (CSC) located in Bangkok, Thailand. Our stroke network consists of different levels of spoke hospitals, ranging from community hospitals where throm...

    Authors: Naruchorn Kijpaisalratana, Aurauma Chutinet, Wasan Akarathanawat, Pakkawan Vongvasinkul and Nijasri C. Suwanwela
    Citation: BMC Neurology 2020 20:45
  15. Autoimmune encephalitis is characterized by neuropsychiatric symptoms associated with brain inflammation. The differential is usually broad and Psychiatry often collaborates with Neurology in diagnostic clarif...

    Authors: Julia Shekunov, Caren J. Blacker, Jennifer L. Vande Voort, Jan-Mendelt Tillema, Paul E. Croarkin and Magdalena Romanowicz
    Citation: BMC Neurology 2020 20:44
  16. Pharmacological treatment of patients with tension-type headache (TTH) includes symptomatic (acute) and prophylactic (preventive) medication. No previous study has investigated variables associated to symptoma...

    Authors: César Fernández-de-las-Peñas, Maria Palacios-Ceña, Matteo Castaldo, Kelun Wang, Ángel Guerrero-Peral, Antonella Catena and Lars Arendt-Nielsen
    Citation: BMC Neurology 2020 20:43
  17. While the burden of neurologic illness in developing countries is increasing, less is known about mortality among patients admitted to sub-Saharan African hospitals with neurologic disease. We sought to charac...

    Authors: Monica M. Diaz, Xin Hu, Brenda T. Fenton, Ivan Kimuli, Allison Lee, Hayley Lindsey, Jeffrey K. Bigelow, Samuel Maiser, Hamada H. Altalib and Jason J. Sico
    Citation: BMC Neurology 2020 20:42
  18. Epilepsy and multiple sclerosis (MS) are two neurological diseases known to greatly influence a patient’s life. The primary aim of this study was to describe the prevalence of sexual dysfunction in patients wi...

    Authors: Marian Petersen, Ellids Kristensen, Laura Giraldi and Annamaria Giraldi
    Citation: BMC Neurology 2020 20:41
  19. Both Deep Brain Stimulation (DBS) and Continuous intrajejunal Levodopa Infusion (CLI) are effective therapies for the treatment of Parkinson’s disease (PD). To our knowledge, no direct head-to-head comparison ...

    Authors: D. van Poppelen, V. Sisodia, R. J. de Haan, M. G. W. Dijkgraaf, P. R. Schuurman, G. J. Geurtsen, A. E. M. Berk, R. M. A. de Bie and J. M. Dijk
    Citation: BMC Neurology 2020 20:40
  20. A significant proportion of ischemic strokes are caused by emboli from atherosclerotic, unstable carotid artery plaques. The selection of patients for endarterectomy in current clinical practice is primarily b...

    Authors: M. Zamani, K. Skagen, H. Scott, D. Russell and M. Skjelland
    Citation: BMC Neurology 2020 20:39
  21. Due to uniform stiffness of standard platinum coils, dense packing of intracranial aneurysms can be difficult to achieve, since stiffer coils can cause microcatheter prolapse or coil migration. SMART coils hav...

    Authors: Behme Daniel, Sack Henrik, Tsogkas Ioannis, Rohde Veit and Psychogios Marios-Nikos
    Citation: BMC Neurology 2020 20:38

    The Correction to this article has been published in BMC Neurology 2020 20:188

  22. We report on a stroke patient with disorder of consciousness (DOC) who underwent repetitive transcranial magnetic stimulation (rTMS) and showed recovery of an injured upper ascending reticular activating syste...

    Authors: Sung Ho Jang and Young Hyeon Kwon
    Citation: BMC Neurology 2020 20:37
  23. To investigate the relationships between blood pressure (BP) circadian rhythms and acute cerebral infarction (ACI), silent cerebral infarction (SCI) and the severity of leukoaraiosis in hypertensive patients.

    Authors: Kang Yang, Xiaodong Zhu, Yulan Feng, Fanxia Shen, Jie Chen, Ningzhen Fu, Jialan Sun and Yi Fu
    Citation: BMC Neurology 2020 20:36
  24. The ability to walk is commonly reported as a top rehabilitation priority for individuals after a stroke. However, not all individuals with stroke are able to practice walking, especially those who require mor...

    Authors: Dennis R. Louie, William B. Mortenson, Melanie Durocher, Robert Teasell, Jennifer Yao and Janice J. Eng
    Citation: BMC Neurology 2020 20:35
  25. Progressive spinal deformity has become a well-recognized complication of intracanal tumors resection. However, the factors affecting post-operative spinal stability remain to be further research. Here, we des...

    Authors: Pangbo Wang, Kang Ma, Tunan Chen, Xingsen Xue, Dada Ma, Shi Wang, Xin Chen, Hui Meng, Gaoyu Cui, Boyuan Gao, Jiangkai Lin, Hua Feng and Weihua Chu
    Citation: BMC Neurology 2020 20:34
  26. Aerobic training has the potential to restore function, stimulate brain repair, and reduce inflammation in people with Multiple Sclerosis (MS). However, disability, fatigue, and heat sensitivity are major barr...

    Authors: Augustine J. Devasahayam, Arthur R. Chaves, Wendy O. Lasisi, Marie E. Curtis, Katie P. Wadden, Liam P. Kelly, Ryan Pretty, Alice Chen, Elizabeth M. Wallack, Caitlin J. Newell, John B. Williams, Hannah Kenny, Matthew B. Downer, Jason McCarthy, Craig S. Moore and Michelle Ploughman
    Citation: BMC Neurology 2020 20:33
  27. While both hypercapnia and hypocapnia are harmful in patients with subarachnoid hemorrhage (SAH), it is unknown whether high-normal PaCO2 values are better than low-normal values. We hypothesized that high-normal...

    Authors: Tilman Reiff, Oliver Barthel, Silvia Schönenberger and Sibu Mundiyanapurath
    Citation: BMC Neurology 2020 20:31
  28. In Moyamoya Angioplasty (MMA), increased apparent diffusion coefficient (ADC) in frontal white matter (WM) with a normal appearance has been associated with frontal hypoperfusion and executive dysfunction. Mul...

    Authors: Lionel Calviere, Paul Loubiere, Melanie Planton, Vanessa Cazzola, Isabelle Catalaa, Helene Mirabel, Jean Christophe Sol and Fabrice Bonneville
    Citation: BMC Neurology 2020 20:30
  29. Necrotizing myopathy (NM) is defined by the dominant pathological feature of necrosis of muscle fibers without substantial lymphocytic inflammatory infiltration. Anti-signal recognition particle (SRP)-antibody...

    Authors: Arika Hara, Ryota Amano, Hiroaki Yokote, Masahide Ijima, Satoshi Zeniya, Toshiki Uchihara, Sawako Yada, Mayumi Masumura, Hidenobu Takei, Ichizo Nishino and Shuta Toru
    Citation: BMC Neurology 2020 20:29
  30. The research on postoperative collateral formation for hemorrhagic moyamoya disease (MMD) evaluated by using digital subtraction angiography (DSA) is limited. Our study objective was to investigate the postope...

    Authors: Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng, Jia Wang, Rong Wang, Yan Zhang, Dong Zhang and Jizong Zhao
    Citation: BMC Neurology 2020 20:28
  31. Alexander disease is a rare neurological disease characterized by progressive spastic quadriparesis and bulbar palsy. Moreover, certain patients with adult-onset Alexander disease were often misdiagnosed as ot...

    Authors: Jongkyu Park, Sung-Tae Park, Jieun Kim and Kyum-Yil Kwon
    Citation: BMC Neurology 2020 20:27
  32. Parkinson’s disease (PD) and atypical parkinsonisms (APD) have overlapping symptoms challenging an early diagnosis. Diagnostic accuracy is important because PD and APD have different prognosis and response to ...

    Authors: Anna Santaella, H. Bea Kuiperij, Anouke van Rumund, Rianne A. J. Esselink, Alain J. van Gool, Bastiaan R. Bloem and Marcel M. Verbeek
    Citation: BMC Neurology 2020 20:26
  33. Galcanezumab, a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days in phase 2 and 3 trials. In t...

    Authors: Mark E. Bangs, David Kudrow, Shufang Wang, Tina M. Oakes, Gisela M. Terwindt, Delphine Magis, Laura Yunes-Medina and Virginia L. Stauffer
    Citation: BMC Neurology 2020 20:25

    The Correction to this article has been published in BMC Neurology 2020 20:90

  34. Most patients with multiple sclerosis (MS) suffer from bladder dysfunction during the course of the disease. This study was conducted to examine the prevalence of these complications among patients with MS.

    Authors: Fatemeh Nazari, Vahid Shaygannejad, Mehrdad Mohammadi Sichani, Marjan Mansourian and Valiollah Hajhashemi
    Citation: BMC Neurology 2020 20:24
  35. Postural instability presents a common and disabling consequence of chemotherapy-induced peripheral neuropathy (CIPN). However, knowledge about postural behavior of CIPN patients is sparse. With this pilot stu...

    Authors: Sarah Kneis, Anja Wehrle, Daniela Dalin, Isabella Katharina Wiesmeier, Johann Lambeck, Albert Gollhofer, Hartmut Bertz and Christoph Maurer
    Citation: BMC Neurology 2020 20:23
  36. Intravenous thrombolysis therapy (IVT) bridged with intra-arterial thrombectomy (IAT) has recently been recommended as favorable treatment option to ensure that the thrombolytic effect is delivered to the affe...

    Authors: Yu-Jun Chang, Chi-Kuang Liu, Wen-Pei Wu, Shih-Chun Wang, Wei-Liang Chen and Chih-Ming Lin
    Citation: BMC Neurology 2020 20:22
  37. Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic glioma, characterized by large pleomorphic and frequently multinucleated cells, spindle and lipidized cells, a dense pericellular reticulin network, and...

    Authors: Noriyuki Watanabe, Eiichi Ishikawa, Hidehiro Kohzuki, Noriaki Sakamoto, Alexander Zaboronok, Masahide Matsuda, Makoto Shibuya and Akira Matsumura
    Citation: BMC Neurology 2020 20:21
  38. Persons with spinal cord injury/dysfunction (SCI/D) often take multiple medications to treat their secondary complications and chronic conditions (multimorbidity). Multiple healthcare and service providers are...

    Authors: Sara J. T. Guilcher, Amanda C. Everall, Tejal Patel, Tanya L. Packer, Sander L. Hitzig, Stephanie R. Cimino and Aisha K. Lofters
    Citation: BMC Neurology 2020 20:20
  39. Parkinson’s disease (PD) is a progressive neurodegenerative movement disorder that is characterized by motor symptoms such as tremor, rigidity, slowness of movement and problems with gait. Large-scale meta-ana...

    Authors: Hui Wu, Hui Li, Zhiqiang Shi, Jiajia Tang, Shuya Mei, Tianyi Ai and Zhenzhou He
    Citation: BMC Neurology 2020 20:19
  40. A new monogenic neurodegenerative disease affecting ribosomal metabolism has recently been identified in association with a monoallelic UBTF putative gain of function variant (NM_001076683.1:c.628G>A, hg19). Phen...

    Authors: Filipa Bastos, Mathieu Quinodoz, Marie-Claude Addor, Beryl Royer-Bertrand, Heidi Fodstad, Carlo Rivolta, Claudia Poloni, Andrea Superti-Furga, Eliane Roulet-Perez and Sebastien Lebon
    Citation: BMC Neurology 2020 20:17
  41. Pain is a common problem for individuals with cerebral palsy (CP). In Sweden, 95% of children and adolescents with CP are followed in a national follow-up programme (CPUP), which includes data on pain. The pur...

    Authors: Elsa Eriksson, Gunnar Hägglund and Ann I. Alriksson-Schmidt
    Citation: BMC Neurology 2020 20:15
  42. Active Rehabilitation (AR) is a community peer-based concept for people with spinal cord injury (SCI) that is primarily delivered through brief residential training programmes. Despite a plethora of positive a...

    Authors: Anestis Divanoglou, Tomasz Tasiemski and Sophie Jörgensen
    Citation: BMC Neurology 2020 20:14
  43. Transverse myelitis (TM) is due to inflammatory spinal cord injury with bilateral neurologic involvement, which is sensory, motor, or autonomic in nature. It may be associated with autoimmune disease, vaccinat...

    Authors: Fangfang Qu, Zhenzhen Qu, Yingqian Lv, Bo Song and Bailin Wu
    Citation: BMC Neurology 2020 20:13
  44. Hypertrophic pachymeningitis (HP) is a rare disorder that involves localized or diffuse thickening of the dura mater. HP is associated with various inflammatory, infectious, and malignant diseases, such as rhe...

    Authors: Eiichiro Amano, Keisuke Uchida, Tasuku Ishihara, Shinichi Otsu, Akira Machida and Yoshinobu Eishi
    Citation: BMC Neurology 2020 20:11
  45. We investigated the potential associations between cerebro-spinal fluid (CSF) levels of phosphorylated tau (P-tau) and total tau (T-tau) with short-term response to cholinesterase inhibitor (ChEI) treatment, l...

    Authors: Carina Wattmo, Kaj Blennow and Oskar Hansson
    Citation: BMC Neurology 2020 20:10
  46. According to the new WHO classification from 2016, molecular profiles have shown to provide reliable information about prognosis and treatment response. The purpose of our study is to evaluate the diagnostic p...

    Authors: Maike Kern, Timo Alexander Auer, Thomas Picht, Martin Misch and Edzard Wiener
    Citation: BMC Neurology 2020 20:8

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