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  1. Studies have shown positive effects of therapeutic exercise on motor- and cognitive function as well as on psychosocial outcomes in persons with multiple sclerosis (MS). A reduction of inflammatory stress thro...

    Authors: Niklas Joisten, Annette Rademacher, Wilhelm Bloch, Alexander Schenk, Max Oberste, Ulrik Dalgas, Dawn Langdon, Daniel Caminada, Mette-Triin Purde, Roman Gonzenbach, Jan Kool, Philipp Zimmer and Jens Bansi
    Citation: BMC Neurology 2019 19:37
  2. Neuromyelitis optica (NMO) is a severe inflammatory autoimmune disorder of the central nervous system and often results in paralysis or blindness. Rituximab (RTX) is a mouse–human chimeric monoclonal antibody ...

    Authors: Fulin Gao, Bingyan Chai, Cheng Gu, Ruipeng Wu, Tong Dong, Yuping Yao and Yi Zhang
    Citation: BMC Neurology 2019 19:36
  3. Nodding syndrome is a poorly understood neurological disorder of unknown aetiology, affecting several thousand children in Africa. There has been a consistent epidemiological association with infection by the ...

    Authors: Richard Idro, Ronald Anguzu, Rodney Ogwang, Pamela Akun, Catherine Abbo, Amos Deogratius Mwaka, Bernard Opar, Phyellister Nakamya, Mark Taylor, Alison Elliott, Angela Vincent, Charles Newton and Kevin Marsh
    Citation: BMC Neurology 2019 19:35
  4. Moyamoya vasculopathy (MMV) associated with Graves’ disease (GD) is a rare condition resulting in ischemic stroke accompanied by thyrotoxicity. Radiological findings of vasculitis have been reported in the wal...

    Authors: Hiroto Ito, Syunsuke Yokoi, Kinya Yokoyama, Takumi Asai, Kenji Uda, Yoshio Araki, Syuntaro Takasu, Rei Kobayashi, Hisashi Okada and Satoshi Okuda
    Citation: BMC Neurology 2019 19:34
  5. Although patients with dementia frequently experience neuropsychological symptoms (NPS) such as agitation, which profoundly impacts patients, caregivers, and the healthcare system, few studies have evaluated t...

    Authors: Myrlene Sanon Aigbogun, Robert Stellhorn, Ann Hartry, Ross A. Baker and Howard Fillit
    Citation: BMC Neurology 2019 19:33
  6. Collagen VI-related myopathies are a spectrum of muscular diseases with features of muscle weakness and atrophy, multiple contractures of joints, distal hyperextensibility, severe respiratory dysfunction and c...

    Authors: Mengxin Bao, Fei Mao, Zhangning Zhao, Gaoting Ma, Guangjun Xu, Wenjuan Xu, Huan Chen and Meijia Zhu
    Citation: BMC Neurology 2019 19:32
  7. Ischemic stroke is a leading cause of mortality and morbidity worldwide. Stenosis or blockage of an artery from atherosclerosis can cause insufficient cerebral blood supply, which leads to ischemic stroke. It ...

    Authors: Yan Jiang, Xiaomin Liu, Yifeng Du and Shengnian Zhou
    Citation: BMC Neurology 2019 19:31
  8. Posterior reversible encephalopathy syndrome (PRES) is a complication that occurs during various diseases’ treatment. Imaging examination is the gold standard for diagnosis. PRES frequently occurrence in patie...

    Authors: Li-Ping Zou, Li-Ying Liu, Hui Li, Yang-Yang Wang, Ying Liu, Jing Chen, Lin-Yan Hu, Meng-Jia Liu, Meng-Na Zhang, Qian Lu and Shu-Fang Ma
    Citation: BMC Neurology 2019 19:30
  9. Individuals with epilepsy who cannot be adequately controlled with anti-epileptic drugs, refractory epilepsy, may be suitable for surgical treatment following detailed assessment. This is a complex process and...

    Authors: Virginia Mumford, Frances Rapport, Patti Shih, Rebecca Mitchell, Andrew Bleasel, Armin Nikpour, Geoffrey Herkes, Amy MacRae, Melissa Bartley, Sanjyot Vagholkar and Jeffrey Braithwaite
    Citation: BMC Neurology 2019 19:29
  10. Periodic alternating ping-pong gaze (PPG) is a rare disease with few reports. To our knowledge, there was no report on anti GQ1b antibody syndrome accompanied by PPG. This paper reported a case of anti GQ1b an...

    Authors: Jingzhe Han, Yanan Xie, Haiyan Yan, Yuecheng Cao, HongmeiWang and Duanhua Cao
    Citation: BMC Neurology 2019 19:28
  11. Autism prevalence continues to grow, yet a universally agreed upon etiology is lacking despite manifold evidence of abnormalities especially in terms of genetics and epigenetics. The authors postulate that the...

    Authors: Frank H. Duffy and Heidelise Als
    Citation: BMC Neurology 2019 19:27
  12. Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presente...

    Authors: Dian He, YunLi Yu, Shan Wu, ShuFen Tian, Hui Yu, Shu Xu and Lan Chu
    Citation: BMC Neurology 2019 19:26
  13. Atrial fibrillation (AF) is present in 15–20% of patients with acute ischemic stroke. Oral anticoagulation reduces the risk of AF-related recurrent stroke but clinical guideline recommendations are rather vagu...

    Authors: Alexander Wutzler, Christos Krogias, Anna Grau, Roland Veltkamp, Peter U. Heuschmann and Karl Georg Haeusler
    Citation: BMC Neurology 2019 19:25
  14. Malnutrition is one of the crucial factors associated with poor prognosis in critical ill patients, yet a significant evidence gap surrounds the management of initial enteral feeding in severe stroke. The Opti...

    Authors: Fang Yuan, Fang Yang, Wei Zhang, Yi Jia, Yaling Ma, Yongcai Qu, Xinglai Wang, Kang Huo, Chengkai Wang, Xiangjun Yuan, Chaohui Song, Bei Zhang and Wen Jiang
    Citation: BMC Neurology 2019 19:24
  15. Serum hematological indices such as the neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) have been used as biomarkers of pathogenic inflammation and prognostication in multiple areas of med...

    Authors: Christopher C. Hemond, Bonnie I. Glanz, Rohit Bakshi, Tanuja Chitnis and Brian C. Healy
    Citation: BMC Neurology 2019 19:23
  16. Endothelial progenitor cells (EPCs) play an important role in ischemic stroke. However, there are few studies on the relationship between EPC and nondisabling ischemic cerebrovascular events. Our aim was to in...

    Authors: Wang Zhao, Libo Zhao, Juan Liao, Yong Luo and Lanying He
    Citation: BMC Neurology 2019 19:22
  17. Fatigability has emerged as an important dimension of physical impairment in patients with Spinal Muscular Atrophy (SMA). At present reliable and valid outcome measures for both mildly and severely affected pa...

    Authors: Bart Bartels, Laura E. Habets, Marloes Stam, Renske I. Wadman, Camiel A. Wijngaarde, Marja A. G. C. Schoenmakers, Tim Takken, Erik H.J. Hulzebos, W. Ludo van der Pol and Janke F. de Groot
    Citation: BMC Neurology 2019 19:21
  18. Currently there are no disease-modifying treatments for Parkinson’s disease dementia (PDD), a condition linked to aggregation of the protein α-synuclein in subcortical and cortical brain areas. One of the lead...

    Authors: C. R. A. Silveira, J. MacKinley, K. Coleman, Z. Li, E. Finger, R. Bartha, S. A. Morrow, J. Wells, M. Borrie, R. G. Tirona, C. A. Rupar, G. Zou, R. A. Hegele, D. Mahuran, P. MacDonald, M. E. Jenkins…
    Citation: BMC Neurology 2019 19:20
  19. Anti leucine-rich glioma inactivated 1 (LGI1) encephalitis is a rare autoimmune encephalitis (AE), characterized by acute or subacute cognitive impairment, faciobrachial dystonic seizures, psychiatric disturba...

    Authors: Xuanting Li, Junliang Yuan, Lei Liu and Wenli Hu
    Citation: BMC Neurology 2019 19:19
  20. Traumatic brain injuries in Uganda are on the increase, however little is known about the neuropsychological outcomes in survivors. This study characterized patients with traumatic brain injury (TBI) and the a...

    Authors: Paul Bangirana, Bruno Giordani, Olive Kobusingye, Letisia Murungyi, Charles Mock, Chandy C. John and Richard Idro
    Citation: BMC Neurology 2019 19:18
  21. The aim was to investigate the autonomic dysfunction between Parkinson’s disease (PD) patients with olfactory dysfunction and PD patients without olfactory dysfunction in southern Chinese population.

    Authors: Xin-Yi Wang, Ying-Ying Han, Gang Li and Bei Zhang
    Citation: BMC Neurology 2019 19:17
  22. Following publication of the original article [1], the authors reported the following errors on their article.

    Authors: Erin Oerton and Andreas Bender
    Citation: BMC Neurology 2019 19:16

    The original article was published in BMC Neurology 2017 17:58

  23. The burden of hospital readmission after stroke is substantial, but little knowledge exists on factors associated with long-term readmission after stroke. In a cohort comprising patients with ischemic stroke a...

    Authors: Anna Therese Bjerkreim, Halvor Naess, Andrej Netland Khanevski, Lars Thomassen, Ulrike Waje-Andreassen and Nicola Logallo
    Citation: BMC Neurology 2019 19:15
  24. The signs and symptoms of acute alcohol intoxication resemble those of vertebrobasilar stroke. Due to their shared symptoms including double vision, nystagmus, dysarthria, and ataxia, the differential diagnosi...

    Authors: Tamas Arokszallasi, Eszter Balogh, Laszlo Csiba, Istvan Fekete, Klara Fekete and Laszlo Olah
    Citation: BMC Neurology 2019 19:14
  25. Epilepsy is one of the most common chronic disabling neurologic diseases. The purpose of our study was to investigate whether there is an association between t-PA (tissue plasminogen activator, rs2020918 and rs46...

    Authors: Wenxiu Han, Pei Jiang, Yujin Guo, Pengfei Xu, Ruili Dang, Gongying Li, Xin He, Dehua Liao and Genquan Yan
    Citation: BMC Neurology 2019 19:13
  26. Living with a chronic condition such as epilepsy can have a debilitating effect on the individual and their carers. Managing epilepsy among people with learning disabilities may present a challenge because of ...

    Authors: Jerry Paul K. Ninnoni
    Citation: BMC Neurology 2019 19:12
  27. Futile reperfusion (poor functional status despite successful reperfusion) was observed in up to 67% of patients enrolled in recent endovascular treatment (EVT) clinical trials. We investigated the impact of b...

    Authors: Sang-Hwa Lee, Beom Joon Kim, Moon-Ku Han, Tai Hwan Park, Kyung Bok Lee, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Jae Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Jun Lee, Soo Joo Lee, Jae Guk Kim, Jong-Moo Park, Kyusik Kang…
    Citation: BMC Neurology 2019 19:11
  28. A few reliable national data concerning the etiology of non-traumatic spinal cord injury (SCI) in sub-Sahara Africa exists, mainly because of the limitations of diagnostic imaging. These are both expensive and...

    Authors: Abdu K. Musubire, David B. Meya, Elly T. Katabira, Ana Claire L. Meyer, Paul R. Bohjanen, David R. Boulware and Frank Minja
    Citation: BMC Neurology 2019 19:10
  29. Spinocerebellar ataxia type 31 (SCA 31) is a slowly progressive neurodegenerative disorder characterized by pure cerebellar ataxia. Unlike other CAG repeat diseases, sleep-related problems have not been report...

    Authors: Kazumasa Shindo, Tohko Sato, Hiroaki Murata, Yuta Ichinose, Takanori Hata and Yoshihisa Takiyama
    Citation: BMC Neurology 2019 19:9
  30. Single acute infarction (SAI) usually had lower risk of stroke recurrence than multiple acute infarctions (MAIs) in minor stroke. To evaluate whether all SAI had lower risk of stroke recurrence than MAIs in mi...

    Authors: Guangyao Wang, Jing Jing, Yuesong Pan, Xia Meng, Xingquan Zhao, Liping Liu, Hao Li, David Wang, Yongjun Wang and Yilong Wang
    Citation: BMC Neurology 2019 19:7
  31. Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disea...

    Authors: Xi Chen, Yusheng Tong, Zhifeng Shi, Hong Chen, Zhong Yang, Yuanyuan Wang, Liang Chen and Jinhua Yu
    Citation: BMC Neurology 2019 19:6
  32. Delayed-release dimethyl fumarate (DMF) has demonstrated efficacy and a favorable benefit-risk profile in phase 2 and 3 studies that enrolled predominantly white patients with relapsing-remitting multiple scle...

    Authors: Takahiko Saida, Takashi Yamamura, Takayuki Kondo, Jang Yun, Minhua Yang, Jie Li, Lalitha Mahadavan, Bing Zhu and Sarah I. Sheikh
    Citation: BMC Neurology 2019 19:5
  33. Several neuroimaging studies have reported neurophysiological alterations in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). However, reported outcomes have been inconsistent, and ...

    Authors: Ye-Hwa Jun, Tae-Hoon Eom, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee and Jung-Min Kim
    Citation: BMC Neurology 2019 19:3
  34. Transient ischemic attack (TIA) is a risk factor of stroke. Modern treatment regimens and changing risk factors in the population justify new estimates of stroke risk after TIA, and evaluation of the recommend...

    Authors: Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Janne Kutschera Sund, Hild Fjærtoft, Stephan Schüler, Jens Wilhelm Horn, Geir Bråthen, Ann-Grete Midtsæther, Åse Hagen Morsund, Marja-Liisa Lillebø, Yngve Müller Seljeseth and Bent Indredavik
    Citation: BMC Neurology 2019 19:2
  35. Stiff Person Syndrome (SPS) is an under-diagnosed disorder that affects mobility and the quality of life of affected patients. The aim of the study is to describe the natural history of SPS, the extent of accu...

    Authors: Goran Rakocevic, Harry Alexopoulos and Marinos C. Dalakas
    Citation: BMC Neurology 2019 19:1
  36. Dopamine agonists (DAs) are efficacious for the treatment of motor and nonmotor symptoms in patients with Parkinson’s disease (PD). The treatment of PD with DAs is often complicated by adverse drug reactions (...

    Authors: Piao Zhang, Yan Li, Kun Nie, Lijuan Wang and Yuhu Zhang
    Citation: BMC Neurology 2018 18:221
  37. Leber’s hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by visual loss consequent to optic nerve atrophy. In some cases, LHON is associated with heterogeneous neurological extraocul...

    Authors: Eleonora Mauri, Robertino Dilena, Antonio Boccazzi, Dario Ronchi, Daniela Piga, Fabio Triulzi, Delia Gagliardi, Roberta Brusa, Irene Faravelli, Nereo Bresolin, Francesca Magri, Stefania Corti and Giacomo P. Comi
    Citation: BMC Neurology 2018 18:220
  38. Multiple acyl-CoA dehydrogenase deficiency (MADD) showed great clinical heterogeneity and poses a challenge to diagnosis. Guillain-Barré syndrome (GBS) is an acute-onset autoimmune-mediated peripheral neuropat...

    Authors: Daojun Hong, Yanyan Yu, Yuyao Wang, Yan Xu and Jun Zhang
    Citation: BMC Neurology 2018 18:219
  39. Unplanned readmission within 31 days of discharge after stroke is a useful indicator for monitoring quality of hospital care. We evaluated the risk factors associated with 31-day unplanned readmission of strok...

    Authors: Tiancai Wen, Baoyan Liu, Xia Wan, Xiaoping Zhang, Jin Zhang, Xuezhong Zhou, Alexander Y. L. Lau and Yanning Zhang
    Citation: BMC Neurology 2018 18:218
  40. Myelin oligodendrocyte glycoprotein immunoglobulin G1 (MOG-IgG1)-associated disease is suggested as a separate disease entity distinct from multiple sclerosis and neuromyelitis optica spectrum disorder. Noneth...

    Authors: Seok-Jin Choi, Boram Kim, Haeng-Jin Lee, Seong-Joon Kim, Sung-Min Kim and Jung-Joon Sung
    Citation: BMC Neurology 2018 18:216
  41. In acute ischemic stroke patients, telestroke technology provides sustainable approaches to improve the use of thrombolysis therapy. How this is achieved as it relates to inclusion or exclusion of clinical ris...

    Authors: Leanne Brecthel, Jordan Gainey, Alexandria Penwell and Thomas I. Nathaniel
    Citation: BMC Neurology 2018 18:215
  42. The Paced Auditory Serial Addition Test (PASAT) is a useful cognitive test in patients with multiple sclerosis (MS), assessing sustained attention and information processing speed. However, the neural underpin...

    Authors: Jordi A. Matias-Guiu, Ana Cortés-Martínez, Paloma Montero, Vanesa Pytel, Teresa Moreno-Ramos, Manuela Jorquera, Miguel Yus, Juan Arrazola and Jorge Matías-Guiu
    Citation: BMC Neurology 2018 18:214
  43. The relationship between cognitive assessment results in multiple sclerosis (MS) and performance in daily activities (DAs) remains unclear. Our study aimed to evaluate the relationship between cognitive functi...

    Authors: G. Fenu, M. Fronza, L. Lorefice, M. Arru, G. Coghe, J. Frau, M. G. Marrosu and E. Cocco
    Citation: BMC Neurology 2018 18:212

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