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Page 49 of 52

  1. Cognitive decline is a major threat to well being in later life. Change scores and regression based models have often been used for its investigation. Most methods used to describe cognitive decline assume ind...

    Authors: Graciela Muniz Terrera, Fiona Matthews and Carol Brayne

    Citation: BMC Neurology 2008 8:16

    Content type: Research article

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  2. Many individuals afflicted with multiple sclerosis (MS) experience a transient worsening of symptoms when body temperature increases due to ambient conditions or physical activity. Resulting symptom exacerbati...

    Authors: Dennis A Grahn, Julie vLS Murray and H Craig Heller

    Citation: BMC Neurology 2008 8:14

    Content type: Research article

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  3. Botulism is a rare disease caused by intoxication leading to muscle weakness and rapidly progressive dysphagia. With adequate therapy signs of recovery can be observed within several days. In the last few year...

    Authors: Inga K Teismann, Olaf Steinstraeter, Tobias Warnecke, Julian Zimmermann, Erich B Ringelstein, Christo Pantev and Rainer Dziewas

    Citation: BMC Neurology 2008 8:13

    Content type: Research article

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  4. The relationship between stroke risk and cognitive function has not previously been examined in a large community living sample other than the Framingham cohort. The objective of this study was to examine the ...

    Authors: David J Llewellyn, Iain A Lang, Jing Xie, Felicia A Huppert, David Melzer and Kenneth M Langa

    Citation: BMC Neurology 2008 8:12

    Content type: Research article

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  5. The EVIDENCE (EVidence of Interferon Dose-response: European North American Comparative Efficacy) study was an international, randomized, open-label, assessor-blinded, parallel-group study assessing the effica...

    Authors: A Traboulsee, A AL-Sabbagh, R Bennett, P Chang and DKB Li

    Citation: BMC Neurology 2008 8:11

    Content type: Research article

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  6. Neuroleptic-induced movement disorders (NIMDs) have overlapping co-morbidity. Earlier studies have described typical clinical movement patterns for individual NIMDs. This study aimed to identify specific movem...

    Authors: Sven Janno, Matti M Holi, Katinka Tuisku and Kristian Wahlbeck

    Citation: BMC Neurology 2008 8:10

    Content type: Research article

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  7. The objective of this study was to analyze factors influencing the risk and timing of Alzheimer's disease (AD) in central Norway. The APOE ε4 allele is the only consistently identified risk factor for late onset ...

    Authors: Sigrid B Sando, Stacey Melquist, Ashley Cannon, Michael L Hutton, Olav Sletvold, Ingvild Saltvedt, Linda R White, Stian Lydersen and Jan O Aasly

    Citation: BMC Neurology 2008 8:9

    Content type: Research article

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  8. Recent pathological studies have suggested that thalamic degeneration may represent a site of non-dopaminergic degeneration in Parkinson's Disease (PD). Our objective was to determine if changes in the thalami...

    Authors: Martin J McKeown, Ashish Uthama, Rafeef Abugharbieh, Samantha Palmer, Mechelle Lewis and Xuemei Huang

    Citation: BMC Neurology 2008 8:8

    Content type: Research article

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  9. Over 50% of patients with upper limb paresis resulting from stroke face long-term impaired arm function and ensuing disability in daily life. Unfortunately, the number of effective treatments aimed at improvin...

    Authors: Jeanine A Verbunt, Henk AM Seelen, Feljandro P Ramos, Bernard HM Michielsen, Wim L Wetzelaer and Martine Moennekens

    Citation: BMC Neurology 2008 8:7

    Content type: Study protocol

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  10. Pesticides and correlated lifestyle factors (e.g., exposure to well-water and farming) are repeatedly reported risk factors for Parkinson's disease (PD), but few family-based studies have examined these relati...

    Authors: Dana B Hancock, Eden R Martin, Gregory M Mayhew, Jeffrey M Stajich, Rita Jewett, Mark A Stacy, Burton L Scott, Jeffery M Vance and William K Scott

    Citation: BMC Neurology 2008 8:6

    Content type: Research article

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  11. In Spain, stroke is one of the major causes of death and the main cause of severe disability in people over 65 years. We analyzed the incidence of ischemic stroke, stroke subtypes, case fatality and disability...

    Authors: María Teresa Alzamora, Marta Sorribes, Antonio Heras, Nicolás Vila, Marisa Vicheto, Rosa Forés, José Sánchez-Ojanguren, Amparo Sancho and Guillem Pera

    Citation: BMC Neurology 2008 8:5

    Content type: Research article

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  12. The main objective of this study was to investigate the angiotensin converting enzyme (ACE) genotype as a possible risk factor for migraine (both with and without aura) compared to controls. We also wanted to exa...

    Authors: Erling Tronvik, Lars J Stovner, Gunnar Bovim, Linda R White, Amanda J Gladwin, Kathryn Owen and Harald Schrader

    Citation: BMC Neurology 2008 8:4

    Content type: Research article

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  13. A software based tool has been developed (Optem) to allow automatize the recommendations of the Canadian Multiple Sclerosis Working Group for optimizing MS treatment in order to avoid subjective interpretation.

    Authors: Juan Luís Ruiz-Peña, Pablo Duque and Guillermo Izquierdo

    Citation: BMC Neurology 2008 8:3

    Content type: Research article

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  14. The use of self-report measurements in clinical settings is increasing. However, in patients with limitations that interfere with reliable self-assessment such as cognitive impairment or mood disturbances, as ...

    Authors: Femke AH van der Linden, Jolijn J Kragt, Margarethe van Bon, Martin Klein, Alan J Thompson, Henk M van der Ploeg, Chris H Polman and Bernard MJ Uitdehaag

    Citation: BMC Neurology 2008 8:2

    Content type: Research article

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  15. Mutations in the genes PRKN and LRRK2 are the most frequent known genetic lesions among Parkinson's disease patients. We have previously reported that in the Portuguese population the LRRK2 c.6055G > A; p.G2019S ...

    Authors: Jose Bras, Rita Guerreiro, Maria Ribeiro, Ana Morgadinho, Cristina Januario, Margarida Dias, Ana Calado, Cristina Semedo, Catarina Oliveira, John Hardy and Andrew Singleton

    Citation: BMC Neurology 2008 8:1

    Content type: Research article

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  16. Complaints of unrefreshing sleep are a prominent component of chronic fatigue syndrome (CFS); yet, polysomnographic studies have not consistently documented sleep abnormalities in CFS patients. We conducted th...

    Authors: Matthias Majer, James F Jones, Elizabeth R Unger, Laura Solomon Youngblood, Michael J Decker, Brian Gurbaxani, Christine Heim and William C Reeves

    Citation: BMC Neurology 2007 7:40

    Content type: Research article

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  17. Locomotor training using body weight support and a treadmill as a therapeutic modality for rehabilitation of walking post-stroke is being rapidly adopted into clinical practice. There is an urgent need for a w...

    Authors: Pamela W Duncan, Katherine J Sullivan, Andrea L Behrman, Stanley P Azen, Samuel S Wu, Stephen E Nadeau, Bruce H Dobkin, Dorian K Rose and Julie K Tilson

    Citation: BMC Neurology 2007 7:39

    Content type: Study protocol

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  18. The pathological processes underlying dementia are poorly understood and so are the markers which identify them. Carnosinase is a dipeptidase found almost exclusively in brain and serum. Carnosinase and its su...

    Authors: Cynthia M Balion, Carolyn Benson, Parminder S Raina, Alexandra Papaioannou, Christopher Patterson and Afisi S Ismaila

    Citation: BMC Neurology 2007 7:38

    Content type: Research article

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  19. Neuroserpin, primarily localized to CNS neurons, inhibits the adverse effects of tissue-type plasminogen activator (tPA) on the neurovascular unit and has neuroprotective effects in animal models of ischemic s...

    Authors: John W Cole, Adam C Naj, Jeffrey R O'Connell, Oscar C Stine, John D Sorkin, Marcella A Wozniak, Barney J Stern, Manuel Yepes, Daniel A Lawrence, Laurie J Reinhart, Dudley K Strickland, Braxton D Mitchell and Steven J Kittner

    Citation: BMC Neurology 2007 7:37

    Content type: Research article

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  20. The presence of antiphospholipid antibodies (APLA) in multiple sclerosis (MS) patients has been reported frequently but no clear relationship between APLA and the clinical and neuroimaging features of MS have ...

    Authors: Carlos J Bidot, Lawrence L Horstman, Wenche Jy, Joaquin J Jimenez, Carlos Bidot Jr, Yeon S Ahn, J Steven Alexander, Eduardo Gonzalez-Toledo, Roger E Kelley and Alireza Minagar

    Citation: BMC Neurology 2007 7:36

    Content type: Research article

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  21. Advanced glycation end-products (AGEs) and their receptor (RAGE) occur in dementia of the Alzheimer's type and diabetic microvascular disease. Accumulation of AGEs relates to risk factors for vascular dementia...

    Authors: Louise Southern, Jonathan Williams and Margaret M Esiri

    Citation: BMC Neurology 2007 7:35

    Content type: Research article

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  22. Mental practice as an additional cognitive therapy is getting increased attention in stroke rehabilitation. A systematic review shows some evidence that several techniques in which movements are rehearsed ment...

    Authors: Susy M Braun, Anna J Beurskens, Susanne M van Kroonenburgh, Jeroen Demarteau, Jos M Schols and Derick T Wade

    Citation: BMC Neurology 2007 7:34

    Content type: Study protocol

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  23. Interruption of flow through of cerebral blood vessels results in acute ischemic stroke. Subsequent breakdown of the blood brain barrier increases cerebral injury by the development of vasogenic edema and seco...

    Authors: Adviye Ergul, Mostafa M Elgebaly, Mary-Louise Middlemore, Weiguo Li, Hazem Elewa, Jeffrey A Switzer, Christiana Hall, Anna Kozak and Susan C Fagan

    Citation: BMC Neurology 2007 7:33

    Content type: Research article

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  24. There is a paucity of clinical studies focused specifically on intracerebral haemorrhages of subcortical topography, a subject matter of interest to clinicians involved in stroke management. This single centre...

    Authors: Adrià Arboix, Raquel Rodríguez-Aguilar, Montserrat Oliveres, Emili Comes, Luis García-Eroles and Joan Massons

    Citation: BMC Neurology 2007 7:32

    Content type: Research article

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  25. Assessment of subjective quality of life (QOL) of persons with multiple sclerosis (MS) could facilitate the detection of psychosocial aspects of disease that may otherwise go unrecognized. The objectives of th...

    Authors: Asmahan F Alshubaili, Abdel W Awadalla, Jude U Ohaeri and Asser A Mabrouk

    Citation: BMC Neurology 2007 7:31

    Content type: Research article

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  26. Chronic spinal cord injury (SCI) can lead to an insidious decline in motor and sensory function in individuals even years after the initial injury and is accompanied by a slow and progressive cytoarchitectural...

    Authors: Milan Radojicic, Gabriel Nistor and Hans S Keirstead

    Citation: BMC Neurology 2007 7:30

    Content type: Research article

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  27. Parkinson's disease (PD) is the second most common neurodegenerative disorder. As there is no definitive diagnostic test, its diagnosis is based on clinical criteria. Recently transcranial duplex scanning (TCD...

    Authors: Annemarie MM Vlaar, Angela EP Bouwmans, Marinus JPG van Kroonenburgh, Werner H Mess, Selma C Tromp, Piet GWM Wuisman, Alfons GH Kessels, Ania Winogrodzka and Wim EJ Weber

    Citation: BMC Neurology 2007 7:28

    Content type: Study protocol

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  28. Parkinson's disease (PD) is the second most common neurodegenerative disorder. One of the most widely used techniques to diagnose PD is a Single Photon Emission Computer Tomography (SPECT) scan to visualise th...

    Authors: Annemarie MM Vlaar, Marinus JPG van Kroonenburgh, Alfons GH Kessels and Wim EJ Weber

    Citation: BMC Neurology 2007 7:27

    Content type: Research article

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  29. In 6-month anti-dementia drug trials, a 4-point change in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is held to be clinically important. We examined how this change compared with me...

    Authors: Kenneth Rockwood, Sherri Fay, Mary Gorman, Daniel Carver and Janice E Graham

    Citation: BMC Neurology 2007 7:26

    Content type: Technical advance

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  30. Occupational and chronic exposure to solvents and metals is considered a possible risk factor for Parkinson's disease and essential tremor. While manufacturing dental prostheses, dental technicians are exposed...

    Authors: Edito Fabrizio, Nicola Vanacore, Marcella Valente, Alfonso Rubino and Giuseppe Meco

    Citation: BMC Neurology 2007 7:24

    Content type: Research article

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  31. The purpose of this study was to investigate the temporal relationship between autonomic changes and pain activation in migraine and tension-type headache induced by stress in a model relevant for everyday off...

    Authors: Rune B Leistad, Trond Sand, Kristian B Nilsen, Rolf H Westgaard and Lars Jacob Stovner

    Citation: BMC Neurology 2007 7:23

    Content type: Research article

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  32. The Contact Heat Evoked Potential Stimulator (CHEPS) rapidly stimulates cutaneous small nerve fibres, and resulting evoked potentials can be recorded from the scalp. We have studied patients with symptoms of s...

    Authors: Duncan D Atherton, Paul Facer, Katherine M Roberts, V Peter Misra, Boris A Chizh, Chas Bountra and Praveen Anand

    Citation: BMC Neurology 2007 7:21

    Content type: Research article

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  33. Matrix metalloproteinases (MMPs) are a family of extracellular endopeptidases that degrade the extracellular matrix and other extracellular proteins. Studies in experimental animals demonstrate that MMPs play ...

    Authors: Armin Buss, Katrin Pech, Byron A Kakulas, Didier Martin, Jean Schoenen, Johannes Noth and Gary A Brook

    Citation: BMC Neurology 2007 7:17

    Content type: Research article

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  34. 'MRI negative PET positive temporal lobe epilepsy' represents a substantial minority of temporal lobe epilepsy (TLE). Clinicopathological and qualitative imaging differences from mesial temporal lobe epilepsy ...

    Authors: Ross P Carne, Terence J O'Brien, Christine J Kilpatrick, Lachlan R MacGregor, Lucas Litewka, Rodney J Hicks and Mark J Cook

    Citation: BMC Neurology 2007 7:16

    Content type: Research article

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  35. Many reports have described that there are fewer differences in AD brain neuropathologic lesions between AD patients and control subjects aged 80 years and older, as compared with the considerable differences ...

    Authors: Enzo Grossi, Massimo P Buscema, David Snowdon and Piero Antuono

    Citation: BMC Neurology 2007 7:15

    Content type: Research article

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  36. Cerebrospinal fluid (CSF) may be valuable for exploring protein markers for the diagnosis of Alzheimer's disease (AD). The prospect of early detection and treatment, to slow progression, holds hope for aging p...

    Authors: Joung Wook Lee, Hong Namkoong, Hyun Kee Kim, Sanghee Kim, Dong Whi Hwang, Hae Ri Na, Seon-Ah Ha, Jae-Ryong Kim and Jin Woo Kim

    Citation: BMC Neurology 2007 7:14

    Content type: Research article

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  37. A few studies have investigated a possible relationship between Alzheimer's disease (AD) and occupations with extremely low frequency magnetic field (MF) exposure. The purpose of this study was to further eval...

    Authors: Zoreh Davanipour, Chiu-Chen Tseng, Pey-Jiuan Lee and Eugene Sobel

    Citation: BMC Neurology 2007 7:13

    Content type: Research article

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  38. Transient receptor potential (TRP) receptors expressed by primary sensory neurons mediate thermosensitivity, and may play a role in sensory pathophysiology. We previously reported that human dorsal root gangli...

    Authors: Paul Facer, Maria A Casula, Graham D Smith, Christopher D Benham, Iain P Chessell, Chas Bountra, Marco Sinisi, Rolfe Birch and Praveen Anand

    Citation: BMC Neurology 2007 7:11

    Content type: Research article

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  39. Brief screening tests have been developed to measure cognitive performance and dementia, yet they measure limited cognitive domains and often lack construct validity. Neuropsychological assessments, while comp...

    Authors: Valerie C Crooks, Thomas D Parsons and J Galen Buckwalter

    Citation: BMC Neurology 2007 7:10

    Content type: Research article

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  40. Frontotemporal Lobar Degeneration (FTLD) thus recently renamed, refers to a spectrum of heterogeneous conditions. This same heterogeneity of presentation represents the major methodological limit for the corre...

    Authors: Barbara Borroni, Mario Grassi, Chiara Agosti, Barbara Paghera, Antonella Alberici, Monica Di Luca, Daniela Perani and Alessandro Padovani

    Citation: BMC Neurology 2007 7:9

    Content type: Research article

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  41. Few studies have examined cognitive functioning of HIV positive patients in sub-Saharan Africa. It cannot be assumed that HIV positive patients in Africa exhibit the same declines as patients in high-resource ...

    Authors: Kevin R Robertson, Noeline Nakasujja, Matthew Wong, Seggane Musisi, Elly Katabira, Thomas D Parsons, Allan Ronald and Ned Sacktor

    Citation: BMC Neurology 2007 7:8

    Content type: Research article

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