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  1. Simple, non-invasive tests for early detection of degenerative dementia by use of biomarkers are urgently required. However, up to the present, no validated extracerebral diagnostic markers for the early diagn...

    Authors: Felix Bermejo-Pareja, Desiree Antequera, Teo Vargas, Jose A Molina and Eva Carro
    Citation: BMC Neurology 2010 10:108
  2. Extracellular gelsolin (GSN) and GC-globulin/Vitamin D-binding protein (DBP) appear to play an important role in clearing the actin from extracellular fluids and in modulating cellular responses to anionic bio...

    Authors: Alina Kułakowska, Nicholas J Ciccarelli, Qi Wen, Barbara Mroczko, Wiesław Drozdowski, Maciej Szmitkowski, Paul A Janmey and Robert Bucki
    Citation: BMC Neurology 2010 10:107
  3. A recent development in non-invasive techniques to predict intracranial pressure (ICP) termed venous ophthalmodynamometry (vODM) has made measurements in absolute units possible. However, there has been little...

    Authors: Henry W Querfurth, Philip Lieberman, Steve Arms, Steve Mundell, Michael Bennett and Craig van Horne
    Citation: BMC Neurology 2010 10:106
  4. Temporal, i.e., 24-hour, weekly, and seasonal patterns in the occurrence of acute cardiovascular and cerebrovascular events are well documented; however, little is known about temporal, especially seasonal, va...

    Authors: Fabrizio Salvi, Ilaria Bartolomei, Michael H Smolensky, Angelo Lorusso, Elena Barbarossa, Anna Maria Malagoni, Paolo Zamboni and Roberto Manfredini
    Citation: BMC Neurology 2010 10:105
  5. Emotional intelligence (EI) is important for personal, social and career success and has been linked to the frontal anterior cingulate, insula and amygdala regions.

    Authors: Michael Hoffmann, Lourdes Benes Cases, Bronwyn Hoffmann and Ren Chen
    Citation: BMC Neurology 2010 10:103
  6. The majority of research on health outcomes after a traumatic brain injury is focused on male participants. Information examining gender differences in health outcomes post traumatic brain injury is limited. T...

    Authors: Angela Colantonio, Jocelyn E Harris, Graham Ratcliff, Susan Chase and Kristina Ellis
    Citation: BMC Neurology 2010 10:102
  7. Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans included in the group of Transmissible Spongiform Encephalopathies or prion diseases. The vast majority of sCJD cases ar...

    Authors: Ana B Rodríguez-Martínez, Joseba M Garrido, Juan J Zarranz, Jose M Arteagoitia, Marian M de Pancorbo, Begoña Atarés, Miren J Bilbao, Isidro Ferrer and Ramón A Juste
    Citation: BMC Neurology 2010 10:99
  8. Vertigo and dizziness are symptoms which are reported frequently in clinical practice. We aimed to develop diagnostic indices for four prevalent vertiginous diseases: benign paroxysmal positional vertigo (BPPV...

    Authors: Otmar Bayer, Jan-Christian Warninghoff and Andreas Straube
    Citation: BMC Neurology 2010 10:98

    The Erratum to this article has been published in BMC Neurology 2011 11:45

  9. Most people with a spinal cord injury rate neuropathic pain as one of the most difficult problems to manage and there are no medical treatments that provide satisfactory pain relief in most people. Furthermore...

    Authors: Matagne Heutink, Marcel WM Post, Peter Luthart, Lilian EMA Pfennings, Catja A Dijkstra and Eline Lindeman
    Citation: BMC Neurology 2010 10:96
  10. In the substantia nigra of Parkinson's disease (PD) patients, increased lipid peroxidation, decreased activities of the mitochondrial complex I of the respiratory chain, catalase and glutathione-peroxidase, an...

    Authors: Pilar del Hoyo, Alberto García-Redondo, Fernando de Bustos, José Antonio Molina, Youssef Sayed, Hortensia Alonso-Navarro, Luis Caballero, Joaquín Arenas, José AG Agúndez and Félix Javier Jiménez-Jiménez
    Citation: BMC Neurology 2010 10:95
  11. Eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor (GEF) and a key regulator of translation initiation under normal and stress conditions, causes an autosomal recessive l...

    Authors: Laetitia Horzinski, Liraz Kantor, Aurélia Huyghe, Raphael Schiffmann, Orna Elroy-Stein, Odile Boespflug-Tanguy and Anne Fogli
    Citation: BMC Neurology 2010 10:94
  12. Infection is a major complication of cerebrospinal fluid shunting procedures. The present report assesses the efficacy of such catheters in both shunts and external ventricular drains (EVDs) against infection ...

    Authors: Raquel Gutiérrez-González, Gregorio R Boto, Cristina Fernández-Pérez and Náyade del Prado
    Citation: BMC Neurology 2010 10:93
  13. Postherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often limited by poor tolerability. We evalua...

    Authors: Lynn R Webster, Marvin Tark, Richard Rauck, Jeffrey K Tobias and Geertrui F Vanhove
    Citation: BMC Neurology 2010 10:92
  14. Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems. It is hypo...

    Authors: Carlo Paribello, Leeping Tao, Anthony Folino, Elizabeth Berry-Kravis, Michael Tranfaglia, Iryna M Ethell and Douglas W Ethell
    Citation: BMC Neurology 2010 10:91
  15. Alzheimer's disease (AD) is common and highly heritable with many genes and gene variants associated with AD in one or more studies, including APOE ε2/ε3/ε4. However, the genetic backgrounds for normal cogniti...

    Authors: Mi-Ryung Han, Gerard D Schellenberg and Li-San Wang
    Citation: BMC Neurology 2010 10:90
  16. Hereditary Spastic Paraplegias (HSP) are characterized by progressive spasticity and weakness of the lower limbs. At least 45 loci have been identified in families with autosomal dominant (AD), autosomal reces...

    Authors: Victoria Álvarez, Elena Sánchez-Ferrero, Christian Beetz, Marta Díaz, Belén Alonso, Ana I Corao, Josep Gámez, Jesús Esteban, Juan F Gonzalo, Samuel I Pascual-Pascual, Adolfo López de Munain, Germán Moris, Renne Ribacoba, Celedonio Márquez, Jordi Rosell, Rosario Marín…
    Citation: BMC Neurology 2010 10:89
  17. There is a need for greater understanding of the impact of multiple sclerosis (MS) from the perspective of individuals with the condition. The South West Impact of MS Project (SWIMS) has been designed to impro...

    Authors: John P Zajicek, Wendy M Ingram, Jane Vickery, Siobhan Creanor, Dave E Wright and Jeremy C Hobart
    Citation: BMC Neurology 2010 10:88
  18. Behavioural and psychological symptoms of dementia (BPSD) are non-cognitive symptoms commonly associated to Alzheimer's disease (AD). The characterization of the clinical profile of AD patients might help to b...

    Authors: Manuel Fernández, Ana L Gobartt and Montse Balañá
    Citation: BMC Neurology 2010 10:87
  19. Rotigotine is a unique dopamine agonist with activity across D1 through D5 receptors as well as select adrenergic and serotonergic sites. This study reports the 2-year follow-up safety and efficacy data of an ...

    Authors: Birgit Högl, Wolfgang H Oertel, Karin Stiasny-Kolster, Peter Geisler, Heike Beneš, Diego García-Borreguero, Claudia Trenkwalder, Werner Poewe, Erwin Schollmayer and Ralf Kohnen
    Citation: BMC Neurology 2010 10:86
  20. The Freezing of Gait Questionnaire (FOGQ) was developed in response to the difficulties of observing and quantifying freezing of gait (FOG) clinically as well as in laboratory settings. However, as the FOGQ is...

    Authors: Maria H Nilsson, Gun-Marie Hariz, Klas Wictorin, Michael Miller, Lars Forsgren and Peter Hagell
    Citation: BMC Neurology 2010 10:85
  21. Shoulder pain is a common complication of a stroke which can impede participation in rehabilitation programs and has been associated with poorer outcomes. The evidence base for current medical and therapeutic ...

    Authors: Zoe A Allen, E Michael Shanahan and Maria Crotty
    Citation: BMC Neurology 2010 10:83
  22. Elevated serum uric acid (SUA) levels can enhance its antioxidant prosperities and reduce the occurrence of cerebral infarction. Significantly elevated SUA levels have been associated with a better prognosis i...

    Authors: Bin Zhang, Cong Gao, Ning Yang, WeiZhi Zhang, XingWang Song, JianRui Yin, ShuXiang Pu, YongHong Yi and QingChun Gao
    Citation: BMC Neurology 2010 10:82
  23. This study aims to investigate and compare the conduction parameters of nerve bundles in the ulnar nerve that innervates the forearm muscles and hand muscles; routine electromyography study merely evaluates th...

    Authors: Attila Oğuzhanoğlu, Sibel Güler, Mustafa Çam and Eylem Değirmenci
    Citation: BMC Neurology 2010 10:81
  24. The syndrome of the sinking skin flap (SSSF) with delayed sensorimotor deficits after craniectomy is not well known and often neglected. Among various postulated causes, there is evidence that disturbed brain ...

    Authors: Andre Kemmling, Thomas Duning, Lars Lemcke, Thomas Niederstadt, Jens Minnerup, Heike Wersching and Martin Marziniak
    Citation: BMC Neurology 2010 10:80
  25. The purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private ...

    Authors: Cheol Ung Choi and Chang Gyu Park
    Citation: BMC Neurology 2010 10:78
  26. The rate of recovery from the vegetative state (VS) is low. Currently, little is known of the mechanisms and cerebral changes that accompany those relatively rare cases of good recovery. Here, we combined func...

    Authors: Davinia Fernández-Espejo, Carme Junque, Damian Cruse, Montserrat Bernabeu, Teresa Roig-Rovira, Neus Fábregas, Eva Rivas and Jose M Mercader
    Citation: BMC Neurology 2010 10:77
  27. Type 2 Diabetes Mellitus (T2DM) and diabetic symmetrical polyneuropathy (DSP) impact multiple modalities of sensation including light touch, temperature, position sense and vibration perception. No study to da...

    Authors: Benjamin S Boyd, Linda Wanek, Andrew T Gray and Kimberly S Topp
    Citation: BMC Neurology 2010 10:75
  28. Within a multi-centre randomised controlled trial in three nursing homes, a process evaluation of a mental practice intervention was conducted. The main aims were to determine if the intervention was performed...

    Authors: Susy M Braun, Jolanda C van Haastregt, Anna J Beurskens, Alexandra I Gielen, Derick T Wade and Jos M Schols
    Citation: BMC Neurology 2010 10:74
  29. Despite extensive research, no reliable biological marker for chronic fatigue syndrome (CFS) has yet been identified. However, hyperactivation of melanotrophs in the pituitary gland and increased levels of pla...

    Authors: Nobue Shishioh-Ikejima, Tokiko Ogawa, Kouzi Yamaguti, Yasuyoshi Watanabe, Hirohiko Kuratsune and Hiroshi Kiyama
    Citation: BMC Neurology 2010 10:73
  30. Cerebrovascular disease is the second commonest cause of death, and over a third of stroke deaths occur in developing countries. To fulfil the current gap on data, this systematic review is focused on the freq...

    Authors: Akram A Hosseini, Davood Sobhani-Rad, Kavian Ghandehari and Hani TS Benamer
    Citation: BMC Neurology 2010 10:72
  31. Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify ge...

    Authors: Carmen Martínez, José A Molina, Hortensia Alonso-Navarro, Félix J Jiménez-Jiménez, José AG Agúndez and Elena García-Martín
    Citation: BMC Neurology 2010 10:71
  32. Many patients with Parkinson's disease (PD) lead a sedentary lifestyle. Promotion of physical activities may beneficially affect the clinical presentation of PD, and perhaps even modify the course of PD. Howev...

    Authors: Marlies van Nimwegen, Arlène D Speelman, Katrijn Smulders, Sebastiaan Overeem, George F Borm, Frank JG Backx, Bastiaan R Bloem and Marten Munneke
    Citation: BMC Neurology 2010 10:70
  33. Measuring quality of life (QOL) helps to delineate mechanisms underlying the interaction of disease and psychosocial factors. In adults, epileptic foci in the left temporal lobe led to lower QOL and higher dep...

    Authors: Krystyna A Mathiak, Małgorzata Łuba, Klaus Mathiak, Katarzyna Karzel, Tomasz Wolańczyk, Elżbieta Szczepanik and Paweł Ostaszewski
    Citation: BMC Neurology 2010 10:69
  34. In posterior cortical atrophy (PCA), there is a progressive impairment of high-level visual functions and parietal damage, which might predict the occurrence of visual neglect. However, neglect may pass undete...

    Authors: Katia Andrade, Dalila Samri, Marie Sarazin, Leonardo C de Souza, Laurent Cohen, Michel Thiebaut de Schotten, Bruno Dubois and Paolo Bartolomeo
    Citation: BMC Neurology 2010 10:68
  35. Depressive disorders are frequent in epilepsy and associated with reduced seizure control. Almost 50% of interictal depressive disorders have to be classified as atypical depressions according to DSM-4 criteri...

    Authors: Arne E Vaaler, Gunnar Morken, Valentina C Iversen, Daniel Kondziella and Olav M Linaker
    Citation: BMC Neurology 2010 10:67
  36. There is an ongoing debate whether essential tremor (ET) represents a monosymptomatic disorder or other neurologic symptoms are compatible with the diagnosis of ET. Many patients with clinically definite ET de...

    Authors: Peter Hedera, Fenna T Phibbs, John Y Fang, Michael K Cooper, P David Charles and Thomas L Davis
    Citation: BMC Neurology 2010 10:66
  37. Metabolic Syndrome (MetSd) is a cluster of vascular risk factors that may influence cerebrovascular pathology during aging. Recently, microstructural white matter (WM) changes detected by diffusion tensor imag...

    Authors: Bàrbara Segura, María Ángeles Jurado, Núria Freixenet, Núria Bargalló, Carme Junqué and Adrià Arboix
    Citation: BMC Neurology 2010 10:64
  38. Catheter ablation of the pulmonary veins has become accepted as a standard therapeutic approach for symptomatic paroxysmal atrial fibrillation (AF). However, there is some evidence for an ablation associated (...

    Authors: Karl Georg Haeusler, Lydia Koch, Juliane Ueberreiter, Matthias Endres, Heinz-Peter Schultheiss, Peter U Heuschmann, Alexander Schirdewan and Jochen B Fiebach
    Citation: BMC Neurology 2010 10:63
  39. National data on dementia prevalence are not always available, yet it may be possible to obtain estimates from large surveys that include dementia screening instruments. In Australia, many of the dementia prev...

    Authors: Kaarin J Anstey, Richard A Burns, Carole L Birrell, David Steel, Kim M Kiely and Mary A Luszcz
    Citation: BMC Neurology 2010 10:62
  40. Animal and human studies suggest that stress experienced early in life has detrimental consequences on brain development, including brain regions involved in cognitive function. Cognitive changes are cardinal ...

    Authors: Matthias Majer, Urs M Nater, Jin-Mann S Lin, Lucile Capuron and William C Reeves
    Citation: BMC Neurology 2010 10:61
  41. The disease burden of human immunodeficiency virus (HIV) - acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in thi...

    Authors: Georgette D Kanmogne, Callixte T Kuate, Lucette A Cysique, Julius Y Fonsah, Sabine Eta, Roland Doh, Dora M Njamnshi, Emilienne Nchindap, Donald R Franklin Jr, Ronald J Ellis, John A McCutchan, Fidele Binam, Dora Mbanya, Robert K Heaton and Alfred K Njamnshi
    Citation: BMC Neurology 2010 10:60
  42. Cerebrotendinous xanthomatosis (CTX) is a rare genetic disorder. Recent studies show that brain damage in CTX patients extends beyond the abnormalities observed on conventional magnetic resonance imaging (MRI)...

    Authors: Chiung-Chih Chang, Chun-Chung Lui, Jiun-Jie Wang, Shu-Hua Huang, Cheng-Hsien Lu, Ching Chen, Chih-Feng Chen, Min-Chien Tu, Chi-Wei Huang and Wen-Neng Chang
    Citation: BMC Neurology 2010 10:59

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