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  1. The purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private ...

    Authors: Cheol Ung Choi and Chang Gyu Park
    Citation: BMC Neurology 2010 10:78
  2. The rate of recovery from the vegetative state (VS) is low. Currently, little is known of the mechanisms and cerebral changes that accompany those relatively rare cases of good recovery. Here, we combined func...

    Authors: Davinia Fernández-Espejo, Carme Junque, Damian Cruse, Montserrat Bernabeu, Teresa Roig-Rovira, Neus Fábregas, Eva Rivas and Jose M Mercader
    Citation: BMC Neurology 2010 10:77
  3. Type 2 Diabetes Mellitus (T2DM) and diabetic symmetrical polyneuropathy (DSP) impact multiple modalities of sensation including light touch, temperature, position sense and vibration perception. No study to da...

    Authors: Benjamin S Boyd, Linda Wanek, Andrew T Gray and Kimberly S Topp
    Citation: BMC Neurology 2010 10:75
  4. Within a multi-centre randomised controlled trial in three nursing homes, a process evaluation of a mental practice intervention was conducted. The main aims were to determine if the intervention was performed...

    Authors: Susy M Braun, Jolanda C van Haastregt, Anna J Beurskens, Alexandra I Gielen, Derick T Wade and Jos M Schols
    Citation: BMC Neurology 2010 10:74
  5. Despite extensive research, no reliable biological marker for chronic fatigue syndrome (CFS) has yet been identified. However, hyperactivation of melanotrophs in the pituitary gland and increased levels of pla...

    Authors: Nobue Shishioh-Ikejima, Tokiko Ogawa, Kouzi Yamaguti, Yasuyoshi Watanabe, Hirohiko Kuratsune and Hiroshi Kiyama
    Citation: BMC Neurology 2010 10:73
  6. Cerebrovascular disease is the second commonest cause of death, and over a third of stroke deaths occur in developing countries. To fulfil the current gap on data, this systematic review is focused on the freq...

    Authors: Akram A Hosseini, Davood Sobhani-Rad, Kavian Ghandehari and Hani TS Benamer
    Citation: BMC Neurology 2010 10:72
  7. Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify ge...

    Authors: Carmen Martínez, José A Molina, Hortensia Alonso-Navarro, Félix J Jiménez-Jiménez, José AG Agúndez and Elena García-Martín
    Citation: BMC Neurology 2010 10:71
  8. Many patients with Parkinson's disease (PD) lead a sedentary lifestyle. Promotion of physical activities may beneficially affect the clinical presentation of PD, and perhaps even modify the course of PD. Howev...

    Authors: Marlies van Nimwegen, Arlène D Speelman, Katrijn Smulders, Sebastiaan Overeem, George F Borm, Frank JG Backx, Bastiaan R Bloem and Marten Munneke
    Citation: BMC Neurology 2010 10:70
  9. Measuring quality of life (QOL) helps to delineate mechanisms underlying the interaction of disease and psychosocial factors. In adults, epileptic foci in the left temporal lobe led to lower QOL and higher dep...

    Authors: Krystyna A Mathiak, Małgorzata Łuba, Klaus Mathiak, Katarzyna Karzel, Tomasz Wolańczyk, Elżbieta Szczepanik and Paweł Ostaszewski
    Citation: BMC Neurology 2010 10:69
  10. In posterior cortical atrophy (PCA), there is a progressive impairment of high-level visual functions and parietal damage, which might predict the occurrence of visual neglect. However, neglect may pass undete...

    Authors: Katia Andrade, Dalila Samri, Marie Sarazin, Leonardo C de Souza, Laurent Cohen, Michel Thiebaut de Schotten, Bruno Dubois and Paolo Bartolomeo
    Citation: BMC Neurology 2010 10:68
  11. Depressive disorders are frequent in epilepsy and associated with reduced seizure control. Almost 50% of interictal depressive disorders have to be classified as atypical depressions according to DSM-4 criteri...

    Authors: Arne E Vaaler, Gunnar Morken, Valentina C Iversen, Daniel Kondziella and Olav M Linaker
    Citation: BMC Neurology 2010 10:67
  12. There is an ongoing debate whether essential tremor (ET) represents a monosymptomatic disorder or other neurologic symptoms are compatible with the diagnosis of ET. Many patients with clinically definite ET de...

    Authors: Peter Hedera, Fenna T Phibbs, John Y Fang, Michael K Cooper, P David Charles and Thomas L Davis
    Citation: BMC Neurology 2010 10:66
  13. Metabolic Syndrome (MetSd) is a cluster of vascular risk factors that may influence cerebrovascular pathology during aging. Recently, microstructural white matter (WM) changes detected by diffusion tensor imag...

    Authors: Bàrbara Segura, María Ángeles Jurado, Núria Freixenet, Núria Bargalló, Carme Junqué and Adrià Arboix
    Citation: BMC Neurology 2010 10:64
  14. Catheter ablation of the pulmonary veins has become accepted as a standard therapeutic approach for symptomatic paroxysmal atrial fibrillation (AF). However, there is some evidence for an ablation associated (...

    Authors: Karl Georg Haeusler, Lydia Koch, Juliane Ueberreiter, Matthias Endres, Heinz-Peter Schultheiss, Peter U Heuschmann, Alexander Schirdewan and Jochen B Fiebach
    Citation: BMC Neurology 2010 10:63
  15. National data on dementia prevalence are not always available, yet it may be possible to obtain estimates from large surveys that include dementia screening instruments. In Australia, many of the dementia prev...

    Authors: Kaarin J Anstey, Richard A Burns, Carole L Birrell, David Steel, Kim M Kiely and Mary A Luszcz
    Citation: BMC Neurology 2010 10:62
  16. Animal and human studies suggest that stress experienced early in life has detrimental consequences on brain development, including brain regions involved in cognitive function. Cognitive changes are cardinal ...

    Authors: Matthias Majer, Urs M Nater, Jin-Mann S Lin, Lucile Capuron and William C Reeves
    Citation: BMC Neurology 2010 10:61
  17. The disease burden of human immunodeficiency virus (HIV) - acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in thi...

    Authors: Georgette D Kanmogne, Callixte T Kuate, Lucette A Cysique, Julius Y Fonsah, Sabine Eta, Roland Doh, Dora M Njamnshi, Emilienne Nchindap, Donald R Franklin Jr, Ronald J Ellis, John A McCutchan, Fidele Binam, Dora Mbanya, Robert K Heaton and Alfred K Njamnshi
    Citation: BMC Neurology 2010 10:60
  18. Cerebrotendinous xanthomatosis (CTX) is a rare genetic disorder. Recent studies show that brain damage in CTX patients extends beyond the abnormalities observed on conventional magnetic resonance imaging (MRI)...

    Authors: Chiung-Chih Chang, Chun-Chung Lui, Jiun-Jie Wang, Shu-Hua Huang, Cheng-Hsien Lu, Ching Chen, Chih-Feng Chen, Min-Chien Tu, Chi-Wei Huang and Wen-Neng Chang
    Citation: BMC Neurology 2010 10:59
  19. Use of Botulinum toxin-A (BoNT-A) for treatment of upper limb spasticity in children with cerebral palsy has become routine clinical practice in many paediatric treatment centres worldwide. There is now high-l...

    Authors: Brian J Hoare, Christine Imms, Hyam Barry Rawicki and Leeanne Carey
    Citation: BMC Neurology 2010 10:58
  20. In facioscapulohumeral dystrophy (FSHD) muscle function is impaired and declines over time. Currently there is no effective treatment available to slow down this decline. We have previously reported that loss ...

    Authors: Nicoline BM Voet, Gijs Bleijenberg, George W Padberg, Baziel GM van Engelen and Alexander CH Geurts
    Citation: BMC Neurology 2010 10:56
  21. As a continuation of the previous findings in human fetuses, accidental finding of an accessory vascular component in the posterior part of CAC of human adult cadavers inspired the authors to present and compa...

    Authors: Ljiljana Vasović, Milena Trandafilović, Ivan Jovanović, Aleksandra Antović, Jovan Stojanović, Miodrag Zdravković and Miroslav Milić
    Citation: BMC Neurology 2010 10:53
  22. Cerebral palsy (CP) may cause severe spasticity, requiring neurosurgical procedures. The most common neurosurgical procedures are continuous infusion of intrathecal baclofen and selective dorsal rhizotomy. Bot...

    Authors: Georges F Vles, Johan S Vles, Maarten van Kleef, Jan van Zundert, Heleen M Staal, Wim E Weber, Lodewijk W van Rhijn, Dan Soudant, H Kerr Graham and Anton J de Louw
    Citation: BMC Neurology 2010 10:52
  23. The metabolism of amyloid precursor protein (APP) and β-amyloid (Aβ) is widely studied in Alzheimer's disease, where Aβ deposition and plaque development are essential components of the pathogenesis. However, ...

    Authors: Niklas Mattsson, Daniel Bremell, Rolf Anckarsäter, Kaj Blennow, Henrik Anckarsäter, Henrik Zetterberg and Lars Hagberg
    Citation: BMC Neurology 2010 10:51
  24. Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA. We assessed the value of this score to predict the vas...

    Authors: Katrin Holzer, Regina Feurer, Suwad Sadikovic, Lorena Esposito, Angelina Bockelbrink, Dirk Sander, Bernhard Hemmer and Holger Poppert
    Citation: BMC Neurology 2010 10:50
  25. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson's Disease (PD) but data on their efficacy are controv...

    Authors: Petros Skapinakis, Eleni Bakola, Georgia Salanti, Glyn Lewis, Athanasios P Kyritsis and Venetsanos Mavreas
    Citation: BMC Neurology 2010 10:49
  26. Data from different studies suggest a favourable association between pretreatment with statins or hypercholesterolemia and outcome after ischaemic stroke. We examined whether there were differences in in-hospi...

    Authors: Adrià Arboix, Luis García-Eroles, Montserrat Oliveres, Cecília Targa, Miquel Balcells and Joan Massons
    Citation: BMC Neurology 2010 10:47
  27. Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that predominantly affects the optic nerves and the spinal cord, and is possibly mediated by an immune mechanism distinct from that of multip...

    Authors: Hideto Nakajima, Takafumi Hosokawa, Masakazu Sugino, Fumiharu Kimura, Jun Sugasawa, Toshiaki Hanafusa and Toshiyuki Takahashi
    Citation: BMC Neurology 2010 10:45
  28. Anti-epileptic drugs (AEDs) are frequently prescribed to persons with HIV/AIDS receiving combination antiretroviral therapy (cART) although the extent of AED use and their interactions with cART are uncertain....

    Authors: Kathy Lee, Pornpun Vivithanaporn, Reed A Siemieniuk, Hartmut B Krentz, Ferdinand Maingat, M John Gill and Christopher Power
    Citation: BMC Neurology 2010 10:44
  29. Fatigue is one of the most commonly reported and debilitating symptoms of multiple sclerosis (MS); approximately two-thirds of people with MS consider it to be one of their three most troubling symptoms. It ma...

    Authors: Peter W Thomas, Sarah Thomas, Paula Kersten, Rosemary Jones, Alison Nock, Vicky Slingsby, Colin Green, Roger Baker, Kate Galvin and Charles Hillier
    Citation: BMC Neurology 2010 10:43
  30. Despite worldwide recognition of the burden of dementia, no epidemiological data is yet available in Portugal. The objective of this study is to estimate the prevalence and describe the pattern of cognitive im...

    Authors: Belina Nunes, Ricardo D Silva, Vitor T Cruz, Jose M Roriz, Joana Pais and Maria C Silva
    Citation: BMC Neurology 2010 10:42
  31. Genetic factors may play a role in susceptibility to spontaneous deep intracerebral hemorrhage (SDICH). Previous studies have shown that TNF-α gene variation was associated with risks of subarachnoid hemorrhage i...

    Authors: Yi-Chun Chen, Fen-Ju Hu, Phoebe Chen, Yih-Ru Wu, Hsiu-Chuan Wu, Sien-Tsong Chen, Guey-Jen Lee-Chen and Chiung-Mei Chen
    Citation: BMC Neurology 2010 10:41
  32. Despite the cardiovascular etiology of stroke, exercise and risk factor modification programs akin to cardiac rehabilitation (CR) are not available. This study aimed to establish the feasibility of adapting a ...

    Authors: Ada Tang, Susan Marzolini, Paul Oh, William E McIlroy and Dina Brooks
    Citation: BMC Neurology 2010 10:40
  33. PC plays an important role in early diagnosis of health disorders, particularly migraine, due to the financial impact of this disease for the society and its impact on patients' quality of life. The aim of the...

    Authors: Miguel J Láinez, Jesús Castillo, Manuel Domínguez, Gemma Palacios, Silvia Díaz and Javier Rejas
    Citation: BMC Neurology 2010 10:39
  34. Fabry patients have symptoms and signs compatible with autonomic dysfunction. These symptoms and signs are considered to be due to impairment of the peripheral nervous system, but findings indicative of autono...

    Authors: Marieke Biegstraaten, Ivo N van Schaik, Wouter Wieling, Frits A Wijburg and Carla EM Hollak
    Citation: BMC Neurology 2010 10:38
  35. Holmes tremor is a rare symptomatic movement disorder. Currently suggested pathophysiological mechanisms of the disease are mostly derived from stroke cases. Although rare, cerebral toxoplasmosis may strengthe...

    Authors: Alain Lekoubou, Rodrigue Njouoguep, Callixte Kuate and André Pascal Kengne
    Citation: BMC Neurology 2010 10:37
  36. Animal models of focal cerebral ischemia are widely used in stroke research. The purpose of our study was to evaluate and compare the cerebral macro- and microvascular architecture of rats in two different mod...

    Authors: Alexander C Langheinrich, Mesut Yeniguen, Anne Ostendorf, Simone Marhoffer, Marian Kampschulte, Georg Bachmann, Erwin Stolz and Tibo Gerriets
    Citation: BMC Neurology 2010 10:36
  37. Assessment of visual fixation is commonly used in the clinical examination of patients with disorders of consciousness. However, different international guidelines seem to disagree whether fixation is compatib...

    Authors: Marie-Aurélie Bruno, Audrey Vanhaudenhuyse, Caroline Schnakers, Mélanie Boly, Olivia Gosseries, Athena Demertzi, Steve Majerus, Gustave Moonen, Roland Hustinx and Steven Laureys
    Citation: BMC Neurology 2010 10:35
  38. Spontaneous intracerebral hemorrhage (ICH) accounts for a high mortality and morbidity. Early prediction of outcome is crucial for optimized care and treatment decision. Copeptin, the C-terminal part of provas...

    Authors: Christian Zweifel, Mira Katan, Philipp Schuetz, Martin Siegemund, Nils G Morgenthaler, Adrian Merlo, Beat Mueller and Mirjam Christ-Crain
    Citation: BMC Neurology 2010 10:34
  39. In patients with Duchenne Muscular Dystrophy (DMD), the absent or diminished dystrophin leads to progressive skeletal muscle and heart failure. We evaluated the role of myocardial inflammation as a precipitati...

    Authors: Sophie Mavrogeni, Antigoni Papavasiliou, Kostas Spargias, Pantelis Constandoulakis, George Papadopoulos, Evangelos Karanasios, Dimitris Georgakopoulos, Genovefa Kolovou, Eftichia Demerouti, Spyridon Polymeros, Loukas Kaklamanis, Anastasios Magoutas, Evangelia Papadopoulou, Vyron Markussis and Dennis V Cokkinos
    Citation: BMC Neurology 2010 10:33
  40. Lacunar syndrome not due to lacunar infarct is poorly characterised. This single centre, retrospective study was conducted to describe the clinical characteristics of patients with lacunar syndrome not due to ...

    Authors: Adrià Arboix, Joan Massons, Luis García-Eroles, Cecilia Targa, Emili Comes and Olga Parra
    Citation: BMC Neurology 2010 10:31
  41. The c.2447G>A (p.R722H) mutation in the gene POLG1 of the catalytic subunit of human mitochondrial polymerase gamma has been previously found in a few occasions but its pathogenicity has remained uncertain. We se...

    Authors: Tuomas Komulainen, Reetta Hinttala, Mikko Kärppä, Leila Pajunen, Saara Finnilä, Hannu Tuominen, Heikki Rantala, Ilmo Hassinen, Kari Majamaa and Johanna Uusimaa
    Citation: BMC Neurology 2010 10:29

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