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  1. Ischemic stroke by septic embolism occurs primarily in the context of infective endocarditis or in patients with a right-to-left shunt and formation of a secondary cerebral abscess is a rare event. Erosion of ...

    Authors: Philipp Albrecht, Mark Stettner, Leila Husseini, Stephan Macht, Sebastian Jander, Colin Mackenzie, Ulrike Oesterlee, Philipp Slotty, Axel Methner, Hans-Peter Hartung and Orhan Aktas
    Citation: BMC Neurology 2012 12:133
  2. We tested the hypothesis that in patients with occlusion of the terminal internal carotid artery and/or the proximal middle cerebral artery, a diffusion abnormality of 70 ml or less is accompanied by a diffusi...

    Authors: Reza Hakimelahi, Albert J Yoo, Julian He, Lee H Schwamm, Michael H Lev, Pamela W Schaefer and Ramon Gilberto González
    Citation: BMC Neurology 2012 12:132
  3. Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of unknown etiology, manifesting as combination of parkinsonism, cerebellar syndrome and dysautonomia. Disease-modifying therapies are ...

    Authors: Peter Novak, Arlene Williams, Paula Ravin, Omar Zurkiya, Amir Abduljalil and Vera Novak
    Citation: BMC Neurology 2012 12:131
  4. The recent SLEEMSA study that evaluated excessive daytime sleepiness (EDS) in Caucasian patients with multiple system atrophy (MSA) demonstrated that EDS was more frequent in patients (28%) than in healthy sub...

    Authors: Takayoshi Shimohata, Hideaki Nakayama, Masahiko Tomita, Tetsutaro Ozawa and Masatoyo Nishizawa
    Citation: BMC Neurology 2012 12:130
  5. Community ambulation is a highly complex skill requiring the ability to adapt to increased environmental complexity and perform multiple tasks simultaneously. After stroke, individuals demonstrate a diminished...

    Authors: Prudence Plummer-D’Amato, Anastasia Kyvelidou, Dagmar Sternad, Bijan Najafi, Raymond M Villalobos and David Zurakowski
    Citation: BMC Neurology 2012 12:129
  6. To examine the effects of a multicomponent exercise program on the cognitive function of older adults with amnestic mild cognitive impairment (aMCI).

    Authors: Takao Suzuki, Hiroyuki Shimada, Hyuma Makizako, Takehiko Doi, Daisuke Yoshida, Kota Tsutsumimoto, Yuya Anan, Kazuki Uemura, Sangyoon Lee and Hyuntae Park
    Citation: BMC Neurology 2012 12:128
  7. Both severe stenosis and completed occlusion in internal carotid artery or its distal branches have been considered the main reasons of cerebral hypoperfusion, which contributes to the washout disturbances of emb...

    Authors: Junliang Han, Fang Yang, Wenrui Jiang, Guangyun Zhang, Zhirong Liu, Xuedong Liu, Feng Xia, Ya Bai, Junhong He, Manxiang Chao and Gang Zhao
    Citation: BMC Neurology 2012 12:127
  8. Maintaining cognitive function is essential for healthy aging and to function autonomously within society. White matter lesions (WMLs) are associated with reduced cognitive function in older adults. However, w...

    Authors: Niousha Bolandzadeh, Jennifer C Davis, Roger Tam, Todd C Handy and Teresa Liu-Ambrose
    Citation: BMC Neurology 2012 12:126
  9. Hyperekplexia (HPX) is a rare non-epileptic disorder manifesting immediately after birth with exaggerated persistent startle reaction to unexpected auditory, somatosensory and visual stimuli, and non-habituati...

    Authors: Mohammed Zein Seidahmed, Mustafa A Salih, Omer B Abdulbasit, Meeralebbae Shaheed, Khalid Al Hussein, Abeer M Miqdad, Abdullah K Al Rasheed, Anas M Alazami, Ibrahim A Alorainy and Fowzan S Alkuraya
    Citation: BMC Neurology 2012 12:125
  10. Only few studies have assessed safety of in utero exposure to glatiramer acetate (GA). Following a previous study assessing the safety of interferon beta (IFNB) pregnancy exposure in multiple sclerosis (MS), w...

    Authors: Marta Giannini, Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Luisa Pastò, Lorenzo Razzolini, Elisa Piscolla, Laura De Giglio, Carlo Pozzilli, Damiano Paolicelli, Maria Trojano, Maria Giovanna Marrosu, Francesco Patti, Loredana La Mantia, Gianluigi Mancardi, Claudio Solaro…
    Citation: BMC Neurology 2012 12:124
  11. Pyrexia after stroke (temperature ≥37.5°C) is associated with poor prognosis, but information on timing of body temperature changes and relationship to stroke severity and subtypes varies.

    Authors: Bartosz Karaszewski, Ralph GR Thomas, Martin S Dennis and Joanna M Wardlaw
    Citation: BMC Neurology 2012 12:123
  12. Chronic fatigue and inactivity are prevalent problems among individuals with multiple sclerosis (MS) and may independently or interactively have detrimental effects on quality of life and ability to participat...

    Authors: Matthew Plow, Marcia Finlayson, Robert W Motl and Francois Bethoux
    Citation: BMC Neurology 2012 12:122
  13. Progressive multifocal leukoencephalopathy (PML), a rare but fatal demyelinating disease caused by JC virus (JCV), occurs mainly in immunocompromised patients. As PML develops in individuals with various under...

    Authors: Kazuo Nakamichi, Hidehiro Mizusawa, Masahito Yamada, Shuji Kishida, Yoshiharu Miura, Toshio Shimokawa, Tomohiko Takasaki, Chang-Kweng Lim, Ichiro Kurane and Masayuki Saijo
    Citation: BMC Neurology 2012 12:121
  14. Tourette syndrome is a neuropsychiatric disorder characterized by motor and phonic tics. Deficient motor inhibition underlying tics is one of the main hypotheses in its pathophysiology. Therefore the question ...

    Authors: Irene Neuner, Jorge Arrubla, Corinna Ehlen, Hildegard Janouschek, Carlos Nordt, Bruno Fimm, Frank Schneider, N Jon Shah and Wolfram Kawohl
    Citation: BMC Neurology 2012 12:120
  15. Mild cognitive impairment (MCI), defined as a transitional zone between normal cognition and dementia, requires a battery of formal neuropsychological tests administered by a trained rater for its diagnosis. T...

    Authors: Qi-hao Guo, Bin Zhou, Qian-hua Zhao, Bei Wang and Zhen Hong
    Citation: BMC Neurology 2012 12:119
  16. Family function may have an influence on the mental health deterioration of the caregivers of dependent family members and it could have a varying importance on the care of dependents. Little attention has bee...

    Authors: Vicente Gil-Guillen, Concepcion Carratala-Munuera, Juan Carlos Andres Ortega, Domingo Orozco-Beltran, José Martínez Ribera, Avelino Pereira Expósito, Pablo Martínez Cánovas, Eduardo Payá Mora, Emilio Mayoral Azofra, Antonio Fernández Giménez, Adriana Lopez-Pineda, Patricia Lorca-Amorrich, Carlos Plaza-Sirvent, Elisabet Berzosa Sola, Ramon Salas-Rico and Angel Fernandez-Garcia
    Citation: BMC Neurology 2012 12:118
  17. Data about the risk factors of stroke are sparse in the Middle East populations. We aimed to determine the potential risk factors and their population attributable fraction (PAF) for stroke in an Iranian popul...

    Authors: Noushin Fahimfar, Davood Khalili, Reza Mohebi, Fereidoun Azizi and Farzad Hadaegh
    Citation: BMC Neurology 2012 12:117
  18. Randomized controlled trials (RCT) on the treatment of severe space-occupying infarction of the middle cerebral artery (malignant MCA infarction) showed that early decompressive hemicraniectomy (DHC) is life s...

    Authors: Hermann Neugebauer, Peter U Heuschmann and Eric Jüttler
    Citation: BMC Neurology 2012 12:115
  19. There are many drugs recommended for pain relief in patients with migraine headache.

    Authors: Hassan Soleimanpour, Rouzbeh Rajaei Ghafouri, Aliakbar Taheraghdam, Dawood Aghamohammadi, Sohrab Negargar, Samad EJ Golzari and Mohsen Abbasnezhad
    Citation: BMC Neurology 2012 12:114
  20. Patients with Parkinson's disease have an elevated risk of pneumonia and randomized trials suggest that this risk may be increased with the dopamine agonist pramipexole. It is uncertain whether pramipexole or ...

    Authors: Pierre Ernst, Christel Renoux, Sophie Dell'Aniello and Samy Suissa
    Citation: BMC Neurology 2012 12:113
  21. Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in ...

    Authors: Tomoko Komagamine, Takahide Nagashima, Masaru Kojima, Norito Kokubun, Toshiki Nakamura, Kenich Hashimoto, Kazuhito Kimoto and Koichi Hirata
    Citation: BMC Neurology 2012 12:112
  22. There is increasing scientific knowledge about the interaction between physiological (musculoskeletal, neuromuscular, cognitive and sensory) systems and their influence on balance and walking impairments in Pa...

    Authors: David Conradsson, Niklas Löfgren, Agneta Ståhle, Maria Hagströmer and Erika Franzén
    Citation: BMC Neurology 2012 12:111
  23. Essential tremor (ET) is one of the commonest movement disorders though the prevalence varies globally. There is paucity of data on ET prevalence in sub-Saharan Africa. The study aimed to determine the prevale...

    Authors: Njideka U Okubadejo, Idowu A Bankole, Oluwadamilola O Ojo, Frank I Ojini and Mustapha A Danesi
    Citation: BMC Neurology 2012 12:110
  24. Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, s...

    Authors: Eufrozina Selariu, Elisabet Zia, Marco Brizzi and Kasim Abul-Kasim
    Citation: BMC Neurology 2012 12:109
  25. Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ra...

    Authors: Aia Elise Jønch, Else Rubæk Danielsen, Carsten Thomsen, Per Meden, Kirsten Svenstrup and Jørgen Erik Nielsen
    Citation: BMC Neurology 2012 12:108
  26. In previous studies we found that MHC2TA +1614 genotype frequency was very different when MS patients with and without human herpesvirus 6 (HHV-6) in serum samples were compared; a different clinical behavior ...

    Authors: Maria Inmaculada Dominguez-Mozo, Marta Garcia-Montojo, Virginia De Las Heras, Angel Garcia-Martinez, Ana Maria Arias-Leal, Ignacio Casanova, Rafael Arroyo and Roberto Alvarez-Lafuente
    Citation: BMC Neurology 2012 12:107
  27. Life satisfaction (LS) of cerebrovascular disease survivors and their family caregivers may relate to socioeconomic factors, impaired functions, health-related quality of life (QoL), but their respective influ...

    Authors: Michèle Baumann, Sophie Couffignal, Etienne Le Bihan and Nearkasen Chau
    Citation: BMC Neurology 2012 12:105
  28. The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in ...

    Authors: Jeanne de la Roche, Martin Leuwer, Klaus Krampfl, Gertrud Haeseler, Reinhard Dengler, Vanessa Buchholz and Jörg Ahrens
    Citation: BMC Neurology 2012 12:104
  29. Low levels of plasma 25-hydroxyvitaminD (25(OH)D) are associated with a higher incidence of multiple sclerosis (MS) due to the immune suppressive properties of vitamin D.

    Authors: Laia Grau-López, Maria Luisa Granada, Dàlia Raïch-Regué, Mar Naranjo-Gómez, Francesc E Borràs-Serres, Eva Martínez-Cáceres and Cristina Ramo-Tello
    Citation: BMC Neurology 2012 12:103
  30. Patients in neurologic in-patient rehabilitation are at risk of cardio- and cerebrovascular events. Microalbuminuria (MAU) is frequent and an important risk predictor but has not been validated in in-patient r...

    Authors: Dirk Sander, Christian Weimar, Peter Bramlage, Tobias Brandt, Ludger Rosin and Mario Siebler
    Citation: BMC Neurology 2012 12:102
  31. Neurogenic claudication (NC) is a common symptom in patients with lumbar spinal stenosis (LSS). The Neurogenic Claudication Outcome Score (NCOS) is a very short instrument for measuring functional status in th...

    Authors: Parisa Azimi, Hassan Reza Mohammadi and Ali Montazeri
    Citation: BMC Neurology 2012 12:101
  32. We noticed that a hypothesis based on the effect of geomagnetic disturbances (GMD) has the ability to explain special features of multiple sclerosis (MS). Areas around geomagnetic 60 degree latitude (GM60L) ex...

    Authors: Seyed Aidin Sajedi and Fahimeh Abdollahi
    Citation: BMC Neurology 2012 12:100
  33. Chronic low back pain (CLBP) has been shown to be associated with various pathophysiological changes at several level of the sensorimotor system, pointing to a general hypersensitivity in CLBP patients. The ai...

    Authors: Christian Puta, Birgit Schulz, Saskia Schoeler, Walter Magerl, Brunhild Gabriel, Holger H W Gabriel, Wolfgang H R Miltner and Thomas Weiss
    Citation: BMC Neurology 2012 12:98
  34. This article reports a rare case of active neurosyphilis in a man with mild to moderate dementia and marked hippocampal atrophy, mimicking early onset Alzheimer’s disease. Few cases have so far described bilat...

    Authors: Shima Mehrabian, Margarita Raycheva, Martina Traykova, Tonya Stankova, Latchezar Penev, Olga Grigorova and Latchezar Traykov
    Citation: BMC Neurology 2012 12:96
  35. The balance between T helper cells Th2- and Th1-related cytokines plays a key role in multiple sclerosis (MS). A shift from a Th1 towards a Th2 cytokine profile could have a beneficial effect on the clinical c...

    Authors: Celia Oreja-Guevara, Jaime Ramos-Cejudo, Luiz Stark Aroeira, Beatriz Chamorro and Exuperio Diez-Tejedor
    Citation: BMC Neurology 2012 12:95
  36. Multiple sclerosis (MS) is a chronic progressive neurological disease and the majority of patients will experience some degree of impaired mobility. We evaluated the prevalence, severity and burden of walking ...

    Authors: James Pike, Edward Jones, Krithika Rajagopalan, James Piercy and Peter Anderson
    Citation: BMC Neurology 2012 12:94
  37. Recently, heterozygous mutations in PRRT2 (Chr 16p11.2) have been identified in Han Chinese, Japanese and Caucasians with paroxysmal kinesigenic dyskinesia. In previous work, a paroxysmal kinesigenic dyskinesia l...

    Authors: Peter Hedera, Jianfeng Xiao, Andreas Puschmann, Dragana Momčilović, Steve W Wu and Mark S LeDoux
    Citation: BMC Neurology 2012 12:93
  38. Compensation of brain injury in multiple sclerosis (MS) may in part work through mechanisms involving neuronal plasticity on local and interregional scales. Mechanisms limiting excessive neuronal activity may ...

    Authors: Daniel Zeller, Su-Yin Dang, David Weise, Peter Rieckmann, Klaus V Toyka and Joseph Classen
    Citation: BMC Neurology 2012 12:92
  39. The aim of this study was to perform a longitudinal assessment using Quantitative Muscle Testing (QMT) in a cohort of ambulant boys affected by Duchenne muscular dystrophy (DMD) and to correlate the results of...

    Authors: Alberto Lerario, Serena Bonfiglio, MariaPia Sormani, Andrea Tettamanti, Sarah Marktel, Sara Napolitano, Stefano Previtali, Marina Scarlato, MariaGrazia Natali-Sora, Eugenio Mercuri, Nereo Bresolin, Tiziana Mongini, Giancarlo Comi, Roberto Gatti, Fabio Ciceri, Giulio Cossu…
    Citation: BMC Neurology 2012 12:91
  40. Central post-stroke pain (CPSP) is a neuropathic pain syndrome associated with somatosensory abnormalities due to central nervous system lesion following a cerebrovascular insult. Post-stroke pain (PSP) refers...

    Authors: Rogério Adas Ayres de Oliveira, Daniel Ciampi de Andrade, André Guelman Gomes Machado and Manoel Jacobsen Teixeira
    Citation: BMC Neurology 2012 12:89
  41. Stroke is the second most common cause of mortality and the leading cause of neurological disability, cognitive impairment and dementia worldwide. Nimodipine is a dihydropyridinic calcium antagonist with a rol...

    Authors: Penglian Wang, Yongjun Wang, Tao Feng, Xingquan Zhao, Yong Zhou, Yilong Wang, Weixiong Shi and Yi Ju
    Citation: BMC Neurology 2012 12:88
  42. Human cytomegalovirus (CMV) is an ubiquitous pathogen capable of modulating the host immune system. Immune dysfunction is common during CMV infection and includes autoimmune phenomena. Here we focus on a case ...

    Authors: Xinling Xu, Peter Bergman, Thomas Willows, Charlotte Tammik, Marie Sund, Tomas Hökfelt, Cecilia Söderberg-Naucler and Stefania Varani
    Citation: BMC Neurology 2012 12:87
  43. This article describes the rationale and design of a population-based survey of dementia in Valladolid (northwestern Spain). The main aim of the study was to assess the epidemiology of dementia and its subtype...

    Authors: Miguel Angel Tola-Arribas, María José Garea, María Isabel Yugueros, Fernando Ortega-Valín, Ana Cerón, Beatriz Fernández-Malvido, Marta González-Touya, Antonio San José, Ana Botrán, Vanessa Iglesias and Bárbara Díaz-Gómez
    Citation: BMC Neurology 2012 12:86

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